Zobrazeno 1 - 10
of 2 154
pro vyhledávání: '"J, Coffey"'
Autor:
Hannah Nelson, Sherman Qu, Jeffrey L. Franklin, Qi Liu, Heather H. Pua, Kasey C. Vickers, Alissa M. Weaver, Robert J. Coffey, James G. Patton
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 805-819 (2024)
Extracellular vesicles and nanoparticles (EVPs) are now recognized as a novel form of cell–cell communication. All cells release a wide array of heterogeneous EVPs with distinct protein, lipid, and RNA content, dependent on the pathophysiological s
Externí odkaz:
https://doaj.org/article/0149ce03e8b64eb8b051c0b241d31077
Autor:
Harsimran Kaur, Cody N. Heiser, Eliot T. McKinley, Lissa Ventura-Antunes, Coleman R. Harris, Joseph T. Roland, Melissa A. Farrow, Hilary J. Selden, Ellie L. Pingry, John F. Moore, Lauren I. R. Ehrlich, Martha J. Shrubsole, Jeffrey M. Spraggins, Robert J. Coffey, Ken S. Lau, Simon N. Vandekar
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Spatially resolved molecular assays provide high dimensional genetic, transcriptomic, proteomic, and epigenetic information in situ and at various resolutions. Pairing these data across modalities with histological features enables powerful
Externí odkaz:
https://doaj.org/article/5020e650cae64416958a5b3aac787054
Autor:
Su Min Joyce Tan, Michael J. Coffey, Katrina Blazek, Neela Sitaram, Isabella Dobrescu, Alberto Motta, Sandra Chuang, Chee Y. Ooi
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Background and aimThe COVID-19 pandemic necessitated the transition to online medical education. This study evaluated the efficacy of online case-based tutorials using a serious game tutorial [PlayMed™ (PM)], as compared to a traditional slideshow
Externí odkaz:
https://doaj.org/article/9317235a715d457b84e66aac08d905d6
Autor:
Nalin H. Maniya, Sonu Kumar, Jeffrey L. Franklin, James N. Higginbotham, Andrew M. Scott, Hui K. Gan, Robert J. Coffey, Satyajyoti Senapati, Hsueh-Chia Chang
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract We present a quantitative sandwich immunoassay for CD63 Extracellular Vesicles (EVs) and a constituent surface cargo, EGFR and its activity state, that provides a sensitive, selective, fluorophore-free and rapid alternative to current EV-bas
Externí odkaz:
https://doaj.org/article/73f922b965a546b2a477dcf2d44e21d8
5‐Fluorouracil treatment represses pseudouridine‐containing miRNA export into extracellular vesicles
Autor:
Shimian Qu, Hannah M. Nelson, Xiao Liu, Yu Wang, Elizabeth M. Semler, Danielle L. Michell, Clark Massick, Jeffrey L. Franklin, John Karijolich, Alissa M. Weaver, Robert J. Coffey, Qi Liu, Kasey C. Vickers, James G. Patton
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 9, Pp n/a-n/a (2024)
Abstract 5‐Fluorouracil (5‐FU) has been used for chemotherapy for colorectal and other cancers for over 50 years. The prevailing view of its mechanism of action is inhibition of thymidine synthase leading to defects in DNA replication and repair.
Externí odkaz:
https://doaj.org/article/6e5702c671f04d8e9a2013298d18c044
Autor:
James Kim, Shihan Xu, Seung‐Ryoung Jung, Alya Nguyen, Yuanhua Cheng, Mengxia Zhao, Bryant S. Fujimoto, Wyatt Nelson, Perry Schiro, Jeffrey L. Franklin, James N. Higginbotham, Robert J. Coffey, Min Shi, Lucia N. Vojtech, Florian Hladik, Muneesh Tewari, John Tigges, Ionita Ghiran, Tijana Jovanovic‐Talisman, Louise C. Laurent, Saumya Das, Olesia Gololobova, Kenneth W. Witwer, Tuoye Xu, Al Charest, Kendall Van Keuren Jensen, Robert L. Raffai, Jennifer C. Jones, Joshua A. Welsh, John P. Nolan, Daniel T. Chiu
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 8, Pp n/a-n/a (2024)
Abstract High‐sensitivity flow cytometers have been developed for multi‐parameter characterization of single extracellular vesicles (EVs), but performance varies among instruments and calibration methods. Here we compare the characterization of i
Externí odkaz:
https://doaj.org/article/7ea6b425e4f14da5b65bb5379df9a944
Autor:
A Q M Robiul Kawser, M Nazmul Hoque, M Shaminur Rahman, Tahsin Islam Sakif, Tracey J Coffey, Tofazzal Islam
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303047 (2024)
The field of fish microbiome research has rapidly been advancing, primarily focusing on farmed or laboratory fish species rather than natural or marine fish populations. This study sought to reveal the distinctive gut bacteriome composition and diver
Externí odkaz:
https://doaj.org/article/c7eea2e861f84a39a4dc1b9e1b610033
Autor:
Bogun Jang, Hyesung Kim, Su‐Hyung Lee, Yoonkyung Won, Izumi Kaji, Robert J Coffey, Eunyoung Choi, James R Goldenring
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 1, Pp n/a-n/a (2024)
Abstract Tuft cells are chemosensory cells associated with luminal homeostasis, immune response, and tumorigenesis in the gastrointestinal tract. We aimed to elucidate alterations in tuft cell populations during gastric atrophy and tumorigenesis in h
Externí odkaz:
https://doaj.org/article/a2ba229ff5854ec7a9ed6d4404be232c
Autor:
Chenguang Zhang, Xiaoye Huo, Yini Zhu, James N. Higginbotham, Zheng Cao, Xin Lu, Jeffrey L. Franklin, Kasey C. Vickers, Robert J. Coffey, Satyajyoti Senapati, Ceming Wang, Hsueh-Chia Chang
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
A magnetic nanoporous membrane is engineered for immunocapture of extracellular vesicles and lipoproteins in heterogeneous physiological fluids, such as plasma and saliva, and quantification of cargo and biomarkers in these nanocarriers.
Externí odkaz:
https://doaj.org/article/18353056538849a099f70b57d61adaa9
Autor:
Hao Liu, Danxiu Li, Lina Sun, Hongqiang Qin, Ahui Fan, Lingnan Meng, Ramona Graves-Deal, Sarah E. Glass, Jeffrey L. Franklin, Qi Liu, Jing Wang, Timothy J. Yeatman, Hao Guo, Hong Zong, Shuilin Jin, Zhiyu Chen, Ting Deng, Ying Fang, Cunxi Li, John Karijolich, James G. Patton, Xin Wang, Yongzhan Nie, Daiming Fan, Robert J. Coffey, Xiaodi Zhao, Yuanyuan Lu
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-18 (2022)
Abstract Background Epithelial-to-mesenchymal transition (EMT) is a process linked to metastasis and drug resistance with non-coding RNAs (ncRNAs) playing pivotal roles. We previously showed that miR-100 and miR-125b, embedded within the third intron
Externí odkaz:
https://doaj.org/article/2ff435c04f444160b7d52b6cb613bda6