Výsledky vyhledávání - "J, Ciesielski"

Akademický článek

Urinary and salivary endocrine measurements to complement Tanner staging in studies of pubertal development.

Autor: Mandy Goldberg, Anna J Ciesielski Jones, John A McGrath, Christie Barker-Cummings, Deborah S Cousins, Lauren M Kipling, Juliana W Meadows, James S Kesner, Michele Marcus, Carolyn Monteilh, Dale P Sandler

Publikováno v: PLoS ONE, Vol 16, Iss 5, p e0251598 (2021)

BackgroundMany studies investigating pubertal development use Tanner staging to assess maturation. Endocrine markers in urine and saliva may provide an objective, sensitive, and non-invasive method for assessing development.ObjectiveOur objective was

Externí odkaz: https://doaj.org/article/8ac1f4067c0341b88be4f7c0a08751aa

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Akademický článek

Two-step mechanism of J-domain action in driving Hsp70 function.

Autor: Bartlomiej Tomiczek, Wojciech Delewski, Lukasz Nierzwicki, Milena Stolarska, Igor Grochowina, Brenda Schilke, Rafal Dutkiewicz, Marta A Uzarska, Szymon J Ciesielski, Jacek Czub, Elizabeth A Craig, Jaroslaw Marszalek

Publikováno v: PLoS Computational Biology, Vol 16, Iss 6, p e1007913 (2020)

J-domain proteins (JDPs), obligatory Hsp70 cochaperones, play critical roles in protein homeostasis. They promote key allosteric transitions that stabilize Hsp70 interaction with substrate polypeptides upon hydrolysis of its bound ATP. Although a rec

Externí odkaz: https://doaj.org/article/6137714d2eb446d5ac4f961e7b40983d

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