Zobrazeno 1 - 10
of 183
pro vyhledávání: '"J, Catalin"'
Autor:
Jean-Louis Fischel, P Rostagno, Patricia Formento, J Catalin, Gérard Milano, Marie-Christine Etienne, Joseph Ciccolini
Publikováno v:
British Journal of Cancer
The combination of 5-fluorouracil-folinic acid and oxaliplatin has led to a significant improvement of chemotherapy efficacy in advanced pretreated colorectal cancer. The objective of the present study was, considering the oxaplatin-5-fluorouracil-fo
Autor:
François Doz, O. van Tellingen, Gilles Vassal, A Iliadis, F Pein, Pascal Chastagner, J Arditti, S. Moretti, D. Frappaz, J. Catalin, Jean-Claude Gentet
Publikováno v:
British Journal of Cancer
The maximum tolerated dose of paclitaxel administered by 24-hour continuous infusion in children is known. Short infusion might offer equivalent antitumour efficacy and reduced haematological toxicity, without increasing the allergic risk. Our aims w
Autor:
P. Guillet, R Favre, A. Nicoara, F. Duffaud, T Pignon, A Durand, J. Catalin, D Bagarry-Liégey
Publikováno v:
La Revue de Médecine Interne. 17:689-698
Resume Depuis sa decouverte en 1948, le methotrexate (MTX) a vu son champ d'application s'etendre et c'est en cherchant a vaincre les resistances a ce medicament que le concept de MTX a haute dose a ete propose. Afin de prescrire une posologie optima
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 35:211-215
The aim of this work was to determine the effects of different exposure times to smoke on carboxyhemoglobin (HbCO) and hepatic enzymate activities in order to adapt a tobacco smoke intoxication model in mice. Mice were exposed to tobacco smoke for va
Publikováno v:
International Journal of Bio-Medical Computing. 36:127-130
Abbott Laboratories has developed a new software package (Abbottbase pharmacokinetic system or PKS package) that employs the principles of pharmacokinetics to assist clinical pharmacologists and clinicians in designing dosage regimens. This software,
Publikováno v:
Cancer. 73:308-313
Background. The authors measured pharmacokinetic parameters before, during, and after immunotherapy by continuous intrapleural infusion of recombinant interleukin-2 (rIL-2) and correlated the resulting data with clinical effects in nine patients with
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 5(5-6)
A bank of readily available, well characterized human hepatic microsomal fractions (29 samples from different livers) has been established. The enzymatic characteristics of each microsome sample were determined using three specific UDP-glucuronosyltr
Publikováno v:
Journal of chemotherapy (Florence, Italy). 15(3)
The human liver metabolism of paclitaxel (Taxol), an anticancer drug, leads to three metabolites: 6alpha-hydroxypaclitaxel, 3'-p-hydroxypaclitaxel and 6alpha,3'-p-dihydroxypaclitaxel. The inter-individual variability of paclitaxel metabolism was inve
Autor:
G. Vassal, L. Drouard-Troalen, S. Urien, P. Chastagner, Etienne Chatelut, François Doz, G. Bastian, J. Catalin, J-C. Gentet, H. Rubie, M. Barberi-Heyob
Publikováno v:
European journal of cancer (Oxford, England : 1990). 39(10)
Individual dosing of carboplatin based on drug monitoring was performed within a multi-centric phase I study based on high AUC-levels in children. Twelve patients (aged 3–17 years old) have been included: 3, 5, and 4 patients at the overall target
Publikováno v:
Oncology Reports.
We determined the toxicity and pharmacokinetics of high-dose intrapleural cisplatin (CDDP) as a treatment of malignant pleural effusions (MPE). Fourteen patients with MPE were enrolled in this study. After complete drainage of the fluid, a catheter w