Zobrazeno 1 - 10
of 3 146
pro vyhledávání: '"J, Casey"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 10, Pp 1-14 (2024)
Abstract Cancer stem cells (CSCs) are a group of specially programmed tumor cells that possess the characteristics of perpetual cell renewal, increased invasiveness, and often, drug resistance. Hence, eliminating CSCs is a major challenge for cancer
Externí odkaz:
https://doaj.org/article/5f3eb008a80846799d0daea493b5cd97
Autor:
Lalitha Vaishnavi Subramanyan, Suhail Ahmed Kabeer Rasheed, Lijin Wang, Sujoy Ghosh, Michelle Shi Ning Ong, Manikandan Lakshmanan, Mei Wang, Patrick J. Casey
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-17 (2024)
Abstract GNA13 (Gα13) is one of two alpha subunit members of the G12/13 family of heterotrimeric G-proteins which mediate signaling downstream of GPCRs. It is known to be essential for embryonic development and vasculogenesis and has been increasing
Externí odkaz:
https://doaj.org/article/ee581b5189c0431d82a0f8403a268c6b
Autor:
Ahmed Daoud, Karim Soliman, Maria Aurora Posadas Salas, Genta Uehara, Sakshi Vaishnav, Wisit Cheungpasitporn, Michael J. Casey
Publikováno v:
Renal Failure, Vol 46, Iss 1 (2024)
Aim Kidney transplant recipients (KTRs), due to their immunosuppressed status, are potentially more susceptible to both the severe effects of COVID-19 and complications in their transplanted organ. The aim of this study is to investigate whether COVI
Externí odkaz:
https://doaj.org/article/47bc1f9ff20542488ca22b28f5ea08b8
Autor:
Madison F Walker, Jingyi Zhang, William Steiner, Pei-I Ku, Ju-Fen Zhu, Zachary Michaelson, Yu-Chen Yen, Annabel Lee, Alyssa B Long, Mattie J Casey, Abhishek Poddar, Isaac B Nelson, Corvin D Arveseth, Falko Nagel, Ryan Clough, Sarah LaPotin, Kristen M Kwan, Stefan Schulz, Rodney A Stewart, John J G Tesmer, Tamara Caspary, Radhika Subramanian, Xuecai Ge, Benjamin R Myers
Publikováno v:
PLoS Biology, Vol 22, Iss 8, p e3002685 (2024)
During Hedgehog (Hh) signal transduction in development and disease, the atypical G protein-coupled receptor (GPCR) SMOOTHENED (SMO) communicates with GLI transcription factors by binding the protein kinase A catalytic subunit (PKA-C) and physically
Externí odkaz:
https://doaj.org/article/dd4df563bde8484e9cf388d6a8c3f333
Autor:
Mattie J. Casey, Priya P. Chan, Qing Li, Ju-Fen Zu, Cicely A. Jette, Missia Kohler, Benjamin R. Myers, Rodney A. Stewart
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114559- (2024)
Summary: Medulloblastoma (MB) is the most common malignant brain tumor in children and is stratified into three major subgroups. The Sonic hedgehog (SHH) subgroup represents ∼30% of all MB cases and has significant survival disparity depending upon
Externí odkaz:
https://doaj.org/article/70661191396a44ad9a078ff7db971aa4
The PUG Flap: Conjoined Profunda Artery Perforator and Upper Gracilis Flap for Breast Reconstruction
Autor:
Isra Abdulwadood, BS, Lacey R. Pflibsen, MD, Nicholas R. Jarvis, MD, Sebastian Winocour, MD, Alanna M. Rebecca, MD, William J. Casey, MD, Edward M. Reece, MD, MBA
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 12, Iss 3, p e5544 (2024)
Summary:. Abdominal-based free flaps are the mainstay of autologous breast reconstruction; however, the region may not be ideal for patients with inadequate soft tissue or history of abdominal surgery. This case describes the use of a novel conjoined
Externí odkaz:
https://doaj.org/article/913e3492f133431db5609b829f6163d4
Autor:
Di Wu, Patrick J. Casey
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7162 (2024)
Gα13 and Gα12, encoded by the GNA13 and GNA12 genes, respectively, are members of the G12 family of Gα proteins that, along with their associated Gβγ subunits, mediate signaling from specific G protein-coupled receptors (GPCRs). Advanced prostat
Externí odkaz:
https://doaj.org/article/69a7b773b6aa43d7a2ecc4d7d06b75fb
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-24 (2023)
Abstract Background Single-cell sequencing (sc-Seq) experiments are producing increasingly large data sets. However, large data sets do not necessarily contain large amounts of information. Results Here, we formally quantify the information obtained
Externí odkaz:
https://doaj.org/article/03c12c4bb60c47eba56ce3c798a3e635