Zobrazeno 1 - 10
of 472
pro vyhledávání: '"J, CONTENT"'
Autor:
H. De Pauw, V. De Gezelle, J. Doutreloigne, A. Van Calster, E. Op de Beeck, R. Van Bolderik, J. Content
Publikováno v:
IEEE Transactions on Circuits and Systems I: Regular Papers. 57:471-480
This paper describes the theory behind the "coil-enhancement" principle: The impedance of an inductor is made controllable as a function of the frequency by means of a transconductance function g m (s) that is located in the feedback loop. In order t
Publikováno v:
Biochemical and Biophysical Research Communications. 214:36-43
We have previously shown that a ribozyme directed against human interleukin-6 (IL-6) mRNA is efficient in vivo, despite its poor activity in vitro on full-length IL-6 mRNA. We compared the effect of the nucleocapsid protein of HIV-1 (NCp7) on the rib
Publikováno v:
Biochemical and Biophysical Research Communications. 210:67-73
Hammerhead ribozymes may be of great therapeutic importance, since they can, in theory, be developed to cleave any undesired target RNA. In order to design ribozymes which are stable against endogenous RNases, we incorporated 2'-acetamido-2'-deoxynuc
Publikováno v:
DNA Sequence. 5:311-314
A polymerase chain reaction assay (Lust J.A. et al. (1992). Cytokine 4:96-100) was used to detect a mRNA coding for a soluble IL-6 receptor in human hepatoma cells. In addition to the expected amplification product, we found a sequence (SR4) which co
Publikováno v:
Blood. 84:3758-3765
We have designed a ribozyme (Rz) that cleaves human interleukin-6 (IL- 6) mRNA in vivo. This Rz was tested in vitro, and was found to give expected size fragments. It was then incorporated into a mammalian expression vector containing the constitutiv
Publikováno v:
Journal of Medical Microbiology. 41:282-290
Summary The polymerase chain reaction (PCR) was used to identify the aacA-aphD, aphA3 and aadC genes, encoding the aminoglycoside-modifying enzymes AAC(6′)-APH(2′), APH(3′)III and ANT(4′ 4"), respectively, and the methicillin resistance deter
Autor:
J.P. Brakenhoff, F.D. de Hon, V. Fontaine, E. ten Boekel, H. Schooltink, S. Rose-John, P.C. Heinrich, J. Content, L.A. Aarden
Publikováno v:
The Journal of biological chemistry, 269 (1
Neutralizing monoclonal antibodies specific for human interleukin-6 (IL-6) bind two distinct sites on the IL-6 protein (sites I and II). Their interference with IL-6 receptor binding suggested that site I is a receptor-binding site of IL-6, whereas s
Publikováno v:
APCCAS
A newly developed ‘integrated services digital network’ (ISDN) splitter with bandstop (BS) topology is presented and compared to an actual ISDN splitter with a traditional low-pass (LP) topology. The LP-to-BS topology change reduced the amount of
Autor:
M. Fauville-Dufaux, B. Vanfleteren, L. Wit, J. P. Vincke, J. P. Vooren, M. D. Yates, E. Serruys, J. Content
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases. 11:797-803
A polymerase chain reaction (PCR) assay was developed for detection of mycobacteria using amplification of a 162 bp region of the genes coding for the mycobacterial antigen 85 complex. Strains belonging to the Mycobacterium tuberculosis complex were
Publikováno v:
Journal of Interferon Research. 12:13-16
Two sublines of L929 cells with different interferon (IFN)-producing capacities synthesized IFN and interleukin-6 (IL-6) simultaneously in response to Sendai virus infection. IFN pretreatment primed the production of both cytokines. However, the diff