Zobrazeno 1 - 10
of 365
pro vyhledávání: '"J, COIGNET"'
Autor:
Attaphol Pawarode, Sheila N.J. Sait, Maurice Barcos, Alain Nganga, Lionel J. Coignet, Maria R. Baer
Publikováno v:
Leukemia Research. 31:1589-1592
The BCR/ABL tyrosine kinase inhibitor imatinib mesylate produces a high rate of cytogenetic responses in patients with Philadelphia (Ph)-positive chronic myeloid leukemia (CML), but secondary clonal chromosome abnormalities may develop in Ph-negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b327e8c5f4dc49ec8fc759b6fe7e27
https://doi.org/10.1016/j.leukres.2007.01.022
https://doi.org/10.1016/j.leukres.2007.01.022
Autor:
Boris W. Kuvshinoff, Shefali Agrawal, Jeff Groth, Charles LeVea, Jihnhee Yu, Lionel J. Coignet, Milind Javle, T. Khoury, John F. Gibbs
Publikováno v:
Journal of Gastrointestinal Surgery
CD24 has been described as an adverse prognostic marker in several malignancies. This study evaluates CD24 expression in cholangiocarcinoma and correlates the findings with clinicopathologic data and patient survival. Between 1996 and 2002, 22 consec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048184e2ec6acc97a3abcbdce621008e
https://doi.org/10.1007/s11605-007-0091-5
https://doi.org/10.1007/s11605-007-0091-5
Autor:
Pushpankur Ghoshal, Qing Zhang, Elizabeth Nacheva, Lucio Miele, Qun Jiang, Sylvie Galiègue-Zouitina, Richard I. Fisher, Christiane Houde, Sanne Weijzen, Daniel Catovsky, Eric Davis, Lynda Li Song, Danny Yagan, Andrei Zlobin, Lionel J. Coignet, Thomas M. Grogan
Publikováno v:
Cancer Research. 65:4554-4561
Indolent non-Hodgkin lymphomas are characterized by a prolonged phase that is typically followed by a clinical progression associated with an accelerated clinical course and short survival time. Previous studies have not identified a consistent cytog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa08f0f3dceb089cb7bc67d33221cca
https://doi.org/10.1158/0008-5472.can-04-4108
https://doi.org/10.1158/0008-5472.can-04-4108
Autor:
Lionel J. Coignet, Zeinab I. Mourad, Giuseppina Nucifora, Nahla Farahat, Fady M. Mikhail, Dalal M. El Kaffash, Hala M. Farawela, Nadia Hatem
Publikováno v:
Genes, Chromosomes and Cancer. 39:110-118
AML1 is among the most frequent targets of chromosomal rearrangements in human leukemias. We report here the molecular analysis of a t(4;21)(q28;q22) that has disrupted AML1 in a patient with de novo T-cell acute lymphoblastic leukemia. By using 3′
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8aeafe8a61a15121f227f7f7041df2d
https://doi.org/10.1002/gcc.10302
https://doi.org/10.1002/gcc.10302
Autor:
Giuseppina Nucifora, Kadreya A. Serry, Fady M. Mikhail, Zeinab I. Mourad, Nadia Hatem, Hala M. Farawela, Lionel J. Coignet, D.M.N.E. El Kaffash
Publikováno v:
Leukemia. 16:658-668
The present study was conducted on a series of 41 Egyptian children with newly diagnosed acute lymphoblastic leukemia (ALL) to investigate TEL and AML1 abnormalities. The TEL-AML1 fusion was observed in six patients both by RT-PCR and FISH analyses,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0e7780ff0826fa83064233024fc542
https://doi.org/10.1038/sj.leu.2402399
https://doi.org/10.1038/sj.leu.2402399
Autor:
Martin J. S. Dyer, Hans G. Drexler, Hilmar Quentmeier, Roderick A.F. MacLeod, Corinna Meyer, L. J. Coignet, J. W. G. Janssen
Publikováno v:
Leukemia. 15:1471-1474
Continuous leukemia-lymphoma cell lines are important research tools, in particular as starting material for the cloning of recurrent translocations. In 1998, we established the continuous leukemia cell line MUTZ-5. The two cell lines MUTZ-6 and MUTZ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388a98c847875bee8b708b4985e116d8
https://doi.org/10.1038/sj.leu.2402212
https://doi.org/10.1038/sj.leu.2402212
Publikováno v:
Hematology/Oncology Clinics of North America. 13:1169-1180
There is an increasing understanding that chromosomal abnormalities play a major role in the pathogenesis of multiple myeloma. Furthermore, they seem to predict the clinical outcome of patients according to the specific abnormalities detected. It is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b477b84d5abd6953eb5a94d33509cecb
https://doi.org/10.1016/s0889-8588(05)70119-2
https://doi.org/10.1016/s0889-8588(05)70119-2
Autor:
Marina Lafage-Pochitaloff, Lionel J. Coignet, Sem Saeland, V Duvert, Jacques Banchereau, Nathalie Renard, Isabelle Durand
Publikováno v:
Blood. 87:5162-5170
Because activated T cells were previously shown to induce proliferation of human normal B-cell precursors (BCP) via the CD40 pathway, we investigated the effects of T cells on leukemic blasts isolated from patients with B-lineage acute lymphoblastic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5da772b49a56c9598ae7a97bfc3d7ccb
https://doi.org/10.1182/blood.v87.12.5162.bloodjournal87125162
https://doi.org/10.1182/blood.v87.12.5162.bloodjournal87125162
Autor:
L J, Coignet
Publikováno v:
Methods in molecular medicine. 61
Structural and numerical chromosomal abnormalities have been observed in all types of malignancies. These events are associated with neoplastic pathogenesis and progression (1). For a long time, conventional cytogenetics analysis was the prevalent ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0173efab04ae551426e62f72f82f65a
https://pubmed.ncbi.nlm.nih.gov/22323258
https://pubmed.ncbi.nlm.nih.gov/22323258
Autor:
Pushpankur Ghoshal, Ashley J. Bigelow, Noreen Ersing, Lionel J. Coignet, Joseph Moran-Giuati, Dominic J. Smiraglia, Asher Chanan-Khan, Angela Szafranek, Timothy Johnson, Alain Nganga, Hervé Avet-Loiseau, Christiane Houde
Publikováno v:
Cancer research. 69(10)
Multiple myeloma (MM) is a clonal B-cell neoplasm that accounts for 10% of all malignant hematologic neoplasms and that affects terminally differentiated B cells (i.e., plasma cells). It is now well recognized that the cytokine interleukin-6 (IL-6) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e23c52769d40969d6825a8e16fd40f
https://pubmed.ncbi.nlm.nih.gov/19417136
https://pubmed.ncbi.nlm.nih.gov/19417136