Zobrazeno 1 - 10
of 446
pro vyhledávání: '"J, Burgers"'
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2199 (2023)
Nitrofurantoin (NFT) is a commonly used antibiotic for the treatment of urinary tract infections that can cause liver toxicity. Despite reports of hepatic adverse events associated with NFT exposure, there is still limited understanding of the interp
Externí odkaz:
https://doaj.org/article/658aa83d30304d5ca3f8f962a74c6934
Autor:
Jan W. J. Burgers
Closely associated with the social elite, the lute occupied a central place in the culture of the Dutch Golden Age. In this first comprehensive study of the instrument's role in seventeenth-century Netherlands, Jan W. J. Burgers explores how it funct
Publikováno v:
Epigenetics, Vol 15, Iss 6-7, Pp 594-603 (2020)
DNA methylation of CpG sites is commonly measured using Illumina Infinium BeadChip platforms. The Infinium MethylationEPIC array has replaced the Infinium Methylation450K array. The two arrays use the same technology, with the EPIC array assaying alm
Externí odkaz:
https://doaj.org/article/df1f7d28e78143c3a7cc6a6f2d4c6408
Autor:
B. I. J. M. Van der Heijden, M. J. Burgers, A. M. Kaan, B. F. Lamberts, K. Migchelbrink, R. C. P. M. Van den Ouweland, T. Meijer
Publikováno v:
SAGE Open, Vol 10 (2020)
An in-depth case study approach was followed and data were collected by means of nine semi-structured interviews with experts from six case organizations. Our findings indicate that gamification of work can be a promising path for working organizatio
Externí odkaz:
https://doaj.org/article/73222deb95ad48a3a8c403feb6caf5ea
Autor:
Elena I. Stepchenkova, Piotr A. Mieczkowski, Thomas A. Kunkel, Adam B. Burkholder, Thomas D. Petes, Denis A. Kiktev, Peter M. J. Burgers, Margaret Dominska, Joseph Dahl, Scott A. Lujan, Tony Zhang
Publikováno v:
Nucleic Acids Research
Iron-sulfur clusters (4Fe–4S) exist in many enzymes concerned with DNA replication and repair. The contribution of these clusters to enzymatic activity is not fully understood. We identified the MET18 (MMS19) gene of Saccharomyces cerevisiae as a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8d3cda85e55d05e987d2244cf4b037
http://europepmc.org/articles/PMC8191807
http://europepmc.org/articles/PMC8191807
Publikováno v:
Nucleic Acids Research
DNA polymerase ζ (Pol ζ) and Rev1 are essential for the repair of DNA interstrand crosslink (ICL) damage. We have used yeast DNA polymerases η, ζ and Rev1 to study translesion synthesis (TLS) past a nitrogen mustard-based interstrand crosslink (I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49628337bc4eb1007895ba5f0724792c
http://europepmc.org/articles/PMC7470978
http://europepmc.org/articles/PMC7470978
Autor:
Peter M. J. Burgers, Elias Tannous
Publikováno v:
Crit Rev Biochem Mol Biol
DNA replication is a highly precise process which usually functions in a perfect rhythm with cell cycle progression. However, cells are constantly faced with various kinds of obstacles such as blocks in DNA replication, lack of availability of precur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4dc33068da16027b10bb979846af0e
https://europepmc.org/articles/PMC8992879/
https://europepmc.org/articles/PMC8992879/
Publikováno v:
Journal of Biological Chemistry. 294:10120-10130
In Saccharomyces cerevisiae, Tel1 protein kinase, the ortholog of human ataxia telangiectasia–mutated (ATM), is activated in response to DNA double-strand breaks. Biochemical studies with human ATM and genetic studies in yeast suggest that recruitm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9999fb4418515255cd09dc3c0a0382f8
https://doi.org/10.1074/jbc.ra119.008410
https://doi.org/10.1074/jbc.ra119.008410
Publikováno v:
Nucleic Acids Research
DNA polymerase delta (Pol δ) is responsible for the elongation and maturation of Okazaki fragments in eukaryotic cells. Proliferating cell nuclear antigen (PCNA) recruits Pol δ to the DNA and serves as a processivity factor. Here, we show that PCNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55aca9ea39640ea72d04eeac77477305
https://doi.org/10.1093/nar/gky1321
https://doi.org/10.1093/nar/gky1321
Autor:
M. Reck, T.E. Ciuleanu, A. Pluzanski, J.S. Lee, R. Bernabe Caro, H. Linardou, J. Burgers, C. Gallardo, M. Nishio, S. Peters, L.G. Paz-Ares, M.D. Hellmann, H. Borghaei, S.S. Ramalingam, K. O’Byrne, N. Hu, J. Bushong, L. Eccles, D. Grootendorst, J.R. Brahmer
Publikováno v:
Annals of Oncology. 32:S1430-S1431
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ded77e72ad1e008a16b0aeb5fda308d3
https://doi.org/10.1016/j.annonc.2021.10.141
https://doi.org/10.1016/j.annonc.2021.10.141