Zobrazeno 1 - 10
of 172
pro vyhledávání: '"J, Burckhardt"'
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100644- (2021)
Summary: Co-immunoprecipitation (co-IP) of protein complexes from cell lysates is widely used to study protein-protein interactions. However, establishing robust co-IP assays often involves considerable optimization. Moreover, co-IP results are frequ
Externí odkaz:
https://doaj.org/article/2922380ea3ff48e18daabcda17689c89
Autor:
Saipraveen Srinivasan, Christoph J Burckhardt, Madhura Bhave, Zhiming Chen, Ping-Hung Chen, Xinxin Wang, Gaudenz Danuser, Sandra L Schmid
Publikováno v:
PLoS Biology, Vol 16, Iss 4, p e2005377 (2018)
Dynamin Guanosine Triphosphate hydrolases (GTPases) are best studied for their role in the terminal membrane fission process of clathrin-mediated endocytosis (CME), but they have also been proposed to regulate earlier stages of CME. Although highly e
Externí odkaz:
https://doaj.org/article/b36b18e7c4d1456782a1147370d1f599
Autor:
Esther Ingold, Colette M. vom Berg-Maurer, Christoph J. Burckhardt, André Lehnherr, Philip Rieder, Philip J. Keller, Ernst H. Stelzer, Urs F. Greber, Stephan C. F. Neuhauss, Matthias Gesemann
Publikováno v:
Biology Open, Vol 4, Iss 2, Pp 146-154 (2015)
The formation of functional neuronal circuits relies on accurate migration and proper axonal outgrowth of neuronal precursors. On the route to their targets migrating cells and growing axons depend on both, directional information from neurotropic cu
Externí odkaz:
https://doaj.org/article/b9c4e5371969467989100c0976c53ac4
Publikováno v:
Viruses, Vol 3, Iss 3, Pp 233-253 (2011)
Unlike transport vesicles or organelles, human adenovirus (HAdV) directly binds to the microtubule minus end-directed motor dynein for transport to the nucleus. The dynein cofactor dynactin enhances nuclear transport of HAdV and boosts infection. To
Externí odkaz:
https://doaj.org/article/f71d5a2de6254197b041da761f573663
Publikováno v:
Viruses, Vol 10, Iss 4, p 166 (2018)
Viruses have a dual nature: particles are “passive substances” lacking chemical energy transformation, whereas infected cells are “active substances” turning-over energy. How passive viral substances convert to active substances, comprising v
Externí odkaz:
https://doaj.org/article/ea2ed80be59b42d4bdb09e59ca5e14de
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100644-(2021)
STAR Protocols
STAR Protocols
Summary Co-immunoprecipitation (co-IP) of protein complexes from cell lysates is widely used to study protein-protein interactions. However, establishing robust co-IP assays often involves considerable optimization. Moreover, co-IP results are freque
Autor:
Mattia Gazzola, Christoph J Burckhardt, Basil Bayati, Martin Engelke, Urs F Greber, Petros Koumoutsakos
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 12, p e1000623 (2009)
Cytoplasmic transport of organelles, nucleic acids and proteins on microtubules is usually bidirectional with dynein and kinesin motors mediating the delivery of cargoes in the cytoplasm. Here we combine live cell microscopy, single virus tracking an
Externí odkaz:
https://doaj.org/article/bceb26f9e3564446ac4dfcdff125b246
Autor:
Christoph J Burckhardt, Urs F Greber
Publikováno v:
PLoS Pathogens, Vol 5, Iss 11, p e1000621 (2009)
How viruses are transmitted across the mucosal epithelia of the respiratory, digestive, or excretory tracts, and how they spread from cell to cell and cause systemic infections, is incompletely understood. Recent advances from single virus tracking e
Externí odkaz:
https://doaj.org/article/6ec0aa098e6343e588462995e9554ca8
Autor:
Sangyoon J. Han, Liya Ding, Timothy J. Mitchison, Edgar Gutierrez, Gaudenz Danuser, Alex Groisman, Christoph J. Burckhardt, Nancy Costigliola, Andressa Mota
Publikováno v:
Proceedings of the National Academy of Sciences. 114:5195-5200
The intermediate filament vimentin is required for cells to transition from the epithelial state to the mesenchymal state and migrate as single cells; however, little is known about the specific role of vimentin in the regulation of mesenchymal migra
Publikováno v:
Dev Cell
Cells probe their surrounding matrix for attachment sites via integrins that are internalized by endocytosis. We find that SH3BP4 regulates integrin surface expression in a signaling-dependent manner via clathrin-coated pits (CCPs). Dephosphorylated