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Akademický článek

Reform or transform? A spectrum of stances towards the economic status quo within ‘new economics’ discourses

Autor: Sam J. Buckton, Jasper O. Kenter, Nibedita Mukherjee, Sandra Waddock, Annela Anger-Kraavi, Simone Martino, Ioan Fazey, Adam P. Hejnowicz, Jane Kabubo-Mariara, Jordan O. Lafayette, Kristen Locy, Chris Scarr

Publikováno v: Global Social Challenges Journal (2024)

‘New economics’ discourses – comprising diverse approaches advocated as more just and sustainable replacements of dominant neoclassical and neoliberal economic perspectives – have been criticised as insufficiently coherent to form the ‘disc

Externí odkaz: https://doaj.org/article/2009ea32d2ef40d2b1704d7898b75a08

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Akademický článek

‘Kesho’ Scenario Development for Supporting Water-Energy Food Security under Future Conditions in Zanzibar

Autor: Rebecca J. S. Newman, Charis Enns, Claudia Capitani, Jessica P. R. Thorn, Colin J. Courtney-Mustaphi, Sam J. Buckton, Eugyen Suzanne Om, Ioan Fazey, Tahir A. Haji, Aziza Y. Nchimbi, Rebecca W. Kariuki, Robert A. Marchant

Publikováno v: Land, Vol 13, Iss 2, p 195 (2024)

Social-ecological interactions mediate water–energy–food security in small developing islands, but community-scale insights are underrepresented in nexus research. These interactions are dynamic in their response to environmental and anthropogeni

Externí odkaz: https://doaj.org/article/6a80c42d3b9a49aaa00a476f6f43b923

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Akademický článek

Towards clinical molecular diagnosis of inherited cardiac conditions: a comparison of bench-top genome DNA sequencers.

Autor: Xinzhong Li, Andrew J Buckton, Samuel L Wilkinson, Shibu John, Roddy Walsh, Tomas Novotny, Iveta Valaskova, Manu Gupta, Laurence Game, Paul J R Barton, Stuart A Cook, James S Ware

Publikováno v: PLoS ONE, Vol 8, Iss 7, p e67744 (2013)

BACKGROUND:Molecular genetic testing is recommended for diagnosis of inherited cardiac disease, to guide prognosis and treatment, but access is often limited by cost and availability. Recently introduced high-throughput bench-top DNA sequencing platf

Externí odkaz: https://doaj.org/article/13a0277dfb734638ae1385c6f6070591

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How butterflies keep their cool: Physical and ecological traits influence thermoregulatory ability and population trends

Autor: Colin Lucas, GE Hitchcock, RI Knock, Jonah M. Walker, Matt Lewis, Eleanor Bladon, Rosa Menéndez, Tom M. Fayle, Matthew P. Hayes, Steven R. Ewing, Stuart Corbett, Andrew J. Bladon, Adam McVeigh, Sam J. Buckton, Edgar C. Turner

Understanding which factors influence the ability of individuals to respond to changing temperatures is fundamental to species conservation under climate change.\ud \ud We investigated how a community of butterflies responded to fine-scale changes in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a02df25557406dacfd68117358c77736

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Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism

Autor: Johanna Känsäkoski, Sandy Ayoub, Tiina Laine, Päivi J. Miettinen, Anna-Pauliina Iivonen, Johanna Hietamäki, Xiaonan Liu, Emma Wakeling, Louise C. Gregory, Matti Hero, Mehul T. Dattani, Nina Brandstack, Andrew J Buckton, Kirsi Vaaralahti, Markku Varjosalo, Taneli Raivio

Publikováno v: The Journal of Clinical Endocrinology and Metabolism

Context Congenital pituitary hormone deficiencies with syndromic phenotypes and/or familial occurrence suggest genetic hypopituitarism; however, in many such patients the underlying molecular basis of the disease remains unknown. Objective To describ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e4c0a878aefdac0e2611dbfaa59acb
http://europepmc.org/articles/PMC7138537

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Increased detection of the HIV-1 reverse transcriptase M184V mutation using mutation-specific minority assays in a UK surveillance study suggests evidence of unrecognized transmitted drug resistance*

Autor: Patricia A. Cane, D Prabhu, John Parry, Caterina Hill, RJ Harris, JA Johnson, C Motamed, Catherine M Lowndes, Deenan Pillay, Andrew J. Buckton, Gary Murphy, N Gill

Publikováno v: HIV Medicine. 12:250-254

Objectives The aim of the study was to estimate the levels of transmitted drug resistance (TDR) in HIV-1 using very sensitive assays to detect minority drug-resistant populations. Methods We tested unlinked anonymous serum specimens from sexual healt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aeaa6418c43e0fc7c6e73104a861a7e9
https://doi.org/10.1111/j.1468-1293.2010.00882.x

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Evaluation of a New Assay in Comparison with Reverse Hybridization and Sequencing Methods for Hepatitis C Virus Genotyping Targeting Both 5′ Noncoding and Nonstructural 5b Genomic Regions

Autor: Ramon Planas, Elisa Martró, Lurdes Matas, Gema Fernández, Verónica Saludes, Andrew J. Buckton, Victoria González, Vicenç Ausina

Publikováno v: Journal of Clinical Microbiology. 46:192-197

We report the evaluation of a new real-time PCR assay for hepatitis C virus (HCV) genotyping. The assay design is such that genotype 1 isolates are typed by amplification targeting the nonstructural 5b (NS5b) subgenomic region. Non-genotype 1 isolate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c972af19b3fcb39d79a89fe22d9c75
https://doi.org/10.1128/jcm.01623-07

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Emergence of occult minority genotype 2b hepatitis C infection in an HIV-1-co-infected patient treated for genotype 5a HCV infection with 48 weeks of pegylated-interferon-α 2b and ribavirin

Autor: R. James, Siew Lin Ngui, Savita Rangarajan, C. G. Teo, Ranjababu Kulasegaram, Andrew J. Buckton, Martin Fisher

Publikováno v: Journal of Clinical Virology. 40:60-63

An HIV-1/hepatitis C virus (HCV) co-infected patient with haemophilia received a 48-week course of pegylated interferon-α-2b and ribavirin therapy for genotype 5a HCV infection. Virological response was achieved at week 24. At the end of treatment,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6282e0f936f18bdf2e9b7d685410e6d5
https://doi.org/10.1016/j.jcv.2007.05.010

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Multitypic Hepatitis C Virus Infection Identified by Real-Time Nucleotide Sequencing of Minority Genotypes

Autor: Mary Ramsay, Imad Ibrahim, Paul E. Klapper, Bharat K. C. Patel, Jo-Anne Kovacs, Catherine Arnold, C. G. Teo, Katie Boast, Andrew J. Buckton, Savita Rangarajan, SL Ngui

Publikováno v: Buckton, A J, Ngui, S-L, Arnold, C, Boast, K, Kovacs, J, Klapper, P E, Patel, B, Ibrahim, I, Rangarajan, S, Ramsay, M E & Teo, C-G 2006, ' Multitypic hepatitis C virus infection identified by real-time nucleotide sequencing of minority genotypes ', Journal of clinical microbiology, vol. 44, no. 8, pp. 2779-2784 . https://doi.org/10.1128/JCM.01638-05

The prevalence of concurrent multitypic hepatitis C virus (HCV) infection is uncertain. A sensitive and specific approach to identifying minority HCV genotypes in blood is presented. Following serum extraction and reverse transcription PCR to amplify

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d81f8baadfbd2a17a02e8c4eaa2444
https://doi.org/10.1128/jcm.01638-05

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