Zobrazeno 1 - 10
of 394
pro vyhledávání: '"J, Buckels"'
Autor:
Emma J. Buckels, Joey Tan, Huai‐Ling Hsu, Yuting Zhu, Christina M. Buchanan, Brya G. Matthews, Kate L. Lee
Publikováno v:
JBMR Plus, Vol 7, Iss 8, Pp n/a-n/a (2023)
ABSTRACT Preptin is derived from the cleavage of the E‐peptide of pro‐insulin‐like growth factor (IGF)‐II and is an insulin secretagogue. Observational studies have linked elevated circulating preptin to metabolic dysfunction in humans; howev
Externí odkaz:
https://doaj.org/article/881df186734f4c5883a47775a23c16b9
Publikováno v:
Frontiers in Nutrition, Vol 8 (2021)
The incidence of obesity in women of reproductive age has significantly increased over the past 100 years. There is a well-established connection between maternal obesity during pregnancy and an increased risk of developing non-communicable cardiomet
Externí odkaz:
https://doaj.org/article/13ba7c8342934cfcb498f8c9d2d54419
Autor:
Brya G Matthews, Sanja Novak, Francesca V Sbrana, Jessica L Funnell, Ye Cao, Emma J Buckels, Danka Grcevic, Ivo Kalajzic
Publikováno v:
eLife, Vol 10 (2021)
The periosteum is the major source of cells involved in fracture healing. We sought to characterize progenitor cells and their contribution to bone fracture healing. The periosteum is highly enriched with progenitor cells, including Sca1+ cells, fibr
Externí odkaz:
https://doaj.org/article/c2412fce9e85442d9dbe5f1250a7d23f
Autor:
C. P. Hedges, B. Shetty, S. C. Broome, C. MacRae, P. Koutsifeli, E. J. Buckels, C. MacIndoe, J. Boix, T. Tsiloulis, B. G. Matthews, S. Sinha, M. Arendse, J. K. Jaiswal, K. M. Mellor, A. J. R. Hickey, P. R. Shepherd, T. L. Merry
Publikováno v:
Nature Aging. 3:162-172
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d08ad6d3cfbeb4a70b7f38dcc81edca
https://doi.org/10.1038/s43587-022-00349-y
https://doi.org/10.1038/s43587-022-00349-y
Autor:
Jennifer A. Hollywood, Prasanna K. Kallingappa, Pang Yuk Cheung, Renita M. Martis, Sree Sreebhavan, Robert D. ‘Atiola, Aparajita Chatterjee, Emma J. Buckels, Brya G. Matthews, Paula M. Lewis, Alan J. Davidson
Publikováno v:
American Journal of Physiology-Renal Physiology. 323:F156-F170
Animal models of disease are essential to perform preclinical testing of new therapies before they can progress to clinical trials. The cystinosis field has been hampered by a lack of suitable animal models that fully recapitulate the disease. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b70a79432587f5b7ef3f62019aecf1e
https://doi.org/10.1152/ajprenal.00277.2021
https://doi.org/10.1152/ajprenal.00277.2021
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 323(6)
Preptin is a 34-amino acid peptide derived from the E-peptide of pro-insulin-like growth factor 2 and is co-secreted with insulin from β-cells. Little is understood about the effects of endogenous preptin on whole body glucose metabolism. We develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c107bd727d5d7586664279ce254db43f
https://pubmed.ncbi.nlm.nih.gov/36459047
https://pubmed.ncbi.nlm.nih.gov/36459047
Autor:
Laurelle Jackson, Jessica Hunter, Sandile Cele, Isabella Markham Ferreira, Andrew C Young, Farina Karim, Rajhmun Madansein, Kaylesh J Dullabh, Chih-Yuan Chen, Noel J Buckels, Yashica Ganga, Khadija Khan, Mikael Boulle, Gila Lustig, Richard A Neher, Alex Sigal
Publikováno v:
eLife, Vol 7 (2018)
HIV has been reported to be cytotoxic in vitro and in lymph node infection models. Using a computational approach, we found that partial inhibition of transmissions of multiple virions per cell could lead to increased numbers of live infected cells.
Externí odkaz:
https://doaj.org/article/f962e22d605a430eaff5df1cc72a02f5
Publikováno v:
In Hepatology 2001 34(4) Part 2:A503-A503
Publikováno v:
Current Osteoporosis Reports. 18:655-665
The adult skeleton contains stem cells involved in growth, homeostasis, and healing. Mesenchymal or skeletal stem cells are proposed to provide precursors to osteoblasts, chondrocytes, marrow adipocytes, and stromal cells. We review the evidence for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434e13a7100e659669c574e67dc22958
https://doi.org/10.1007/s11914-020-00622-2
https://doi.org/10.1007/s11914-020-00622-2
Autor:
Ana-Mishel Spiroski, Emma J Buckels, Mark H. Oliver, Frank H. Bloomfield, Anne L. Jaquiery, Jane E. Harding
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 321(4)
Fetal growth restriction (FGR) is associated with decreased insulin secretory capacity and decreased insulin sensitivity in muscle in adulthood. We investigated whether intra-amniotic IGF-I treatment in late gestation mitigated the adverse effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916db561834d3d698f3dde6427654650
https://pubmed.ncbi.nlm.nih.gov/34459219
https://pubmed.ncbi.nlm.nih.gov/34459219