Zobrazeno 1 - 10
of 51
pro vyhledávání: '"J, Bruynseels"'
Autor:
Tony Vangeneugden, J.Michael Marberger, Monique Janssens, Jens Rassweiler, Peter De Porre, Louis Denis, Robin Murray, J. Bruynseels, Francesco Boccardo, Jan E. Johansson, Frans J.M. Debruyne, C.J. Tyrrell, Yves Fradet, Daniel Brune
Publikováno v:
Urology. 52:72-81
Objectives. To compare the efficacy of oral liarozole, the first retinoic acid metabolism-blocking agent (RAMBA) to be developed as differentiation therapy for human solid tumors, with that of cyproterone acetate (CPA), an antiandrogen for the treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99c0cf64c1c272de1cb00d0afea53a73
https://doi.org/10.1016/s0090-4295(98)00129-0
https://doi.org/10.1016/s0090-4295(98)00129-0
Autor:
P. Fernandez del Moral, Louis Denis, J. Bruynseels, P. De Porre, G.A. Dijkman, Frans M.J. Debruyne
Publikováno v:
The Prostate. 33:26-31
BACKGROUND Liarozole is an imidazole derivative that has been identified as an inhibitor of the cytochrome P450-dependent all-trans retinoid acid (RA) breakdown. RA is one of the principal endogenous compounds that controls growth and differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce44fb1ee44517148362093fda694d99
https://doi.org/10.1002/(sici)1097-0045(19970915)33:1<26::aid-pros5>3.0.co
https://doi.org/10.1002/(sici)1097-0045(19970915)33:1<26::aid-pros5>3.0.co
Publikováno v:
Oncology Research and Treatment. 16:22-25
Background: Retinoic acid, the intracellular metabolite of vitamin A, induces differentiation in glioblastoma cultures and recognizes nuclear retinoic acid (RA) receptors in human g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb369656e19e6139e651195527a1f95b
https://doi.org/10.1159/000218219
https://doi.org/10.1159/000218219
Autor:
Willem K. Amery, J. Bruynseels
Publikováno v:
International Journal of Immunopharmacology. 14:481-486
The history of the use of levamisole in man is summarized, from its start as an anthelmintic in the early sixties, through its world-wide recognition as an immunotropic agent especially in the seventies and early eighties, and its return to clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db7cbf156416213543cbdef0aeee400
https://doi.org/10.1016/0192-0561(92)90179-o
https://doi.org/10.1016/0192-0561(92)90179-o
Autor:
Charlie Bowden, H. Vanden Bossche, A. Van Peer, P. A. J. Janssen, R. Van Ginckel, E. Snoeck, J. Bruynseels, R. De Coster, W. Wouters, R.W. Tuman
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 37:335-341
R76713 is a novel triazole derivative which selectively blocks the cytochrome P450-dependent aromatase. In human placental microsomes, in FSH-stimulated rat and human granulosa cells and in human adipose stromal cells, 50% inhibition of estradiol bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::811edfb2ff27aaf7561e490a8eb6a34f
https://doi.org/10.1016/0960-0760(90)90482-z
https://doi.org/10.1016/0960-0760(90)90482-z
Autor:
A. Raeymaekers, G. Vanden Bussche, Gerard Charles Sanz, E. Snoeck, R. De Coster, J. Bruynseels, W. Wouters, H. Vanden Bossche, M.-C. Coene, P. Van Rooy, G. Willemsens, Eddy Jean Edgard Freyne, P. A. J. Janssen
Publikováno v:
The Prostate. 16:345-357
R 75251, a new imidazole derivative, inhibited the conversion of androgens to estrogens, of progestins to androstenedione and testosterone, and of 11-deoxycorticosterone to corticosterone in human placenta microsomes, subcellular fraction of rat test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30ace7e98bb9f93cd53d728f40bbbaa
https://doi.org/10.1002/pros.2990160409
https://doi.org/10.1002/pros.2990160409
Publikováno v:
Oxygen Sensing ISBN: 9780306463679
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21bdb7fa10c9c17be17e8d15d123dbcd
https://doi.org/10.1007/0-306-46825-5_38
https://doi.org/10.1007/0-306-46825-5_38
Autor:
L. M. Tye, Michael Crump, Nancy Wadden, Paul E. Goss, Caroline Reid, Amit M. Oza, Roland De Coster, Rakesh Goel, Jean-Marc Nabholtz, J. Bruynseels
Publikováno v:
Breast cancer research and treatment. 59(1)
This phase II study of liarozole fumarate (R85246, liarozole), a novel imidazole with retinomimetic and aromatase inhibitory effects, was designed to determine the efficacy and tolerability in postmenopausal women with advanced breast cancer in progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadba33a8ef7177f827cfb8c1cedd711
https://pubmed.ncbi.nlm.nih.gov/10752680
https://pubmed.ncbi.nlm.nih.gov/10752680
Publikováno v:
Oncology. 56(2)
RivizorTM (vorozole) is a new, highly potent and selective third-generation aromatase inhibitor for treatment of advanced breast cancer. In an open-label study, 30 postmenopausal women failing tamoxifen therapy received Rivizor 2.5 mg once daily unti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6294e4e8dd1d9f7c3e4cd7b228e990f8
https://pubmed.ncbi.nlm.nih.gov/9949297
https://pubmed.ncbi.nlm.nih.gov/9949297
Autor:
F J, Debruyne, R, Murray, Y, Fradet, J E, Johansson, C, Tyrrell, F, Boccardo, L, Denis, J M, Marberger, D, Brune, J, Rassweiler, T, Vangeneugden, J, Bruynseels, M, Janssens, P, De Porre
Publikováno v:
Urology. 52(1)
To compare the efficacy of oral liarozole, the first retinoic acid metabolism-blocking agent (RAMBA) to be developed as differentiation therapy for human solid tumors, with that of cyproterone acetate (CPA), an antiandrogen for the treatment of metas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a943abd87854a6835aaa8da38d57901d
https://pubmed.ncbi.nlm.nih.gov/9671874
https://pubmed.ncbi.nlm.nih.gov/9671874