Zobrazeno 1 - 10
of 109
pro vyhledávání: '"J, Bothwell"'
Autor:
Myar Mohamed, Anastasia K. Klenke, Maksim V. Anokhin, Harouna Amadou, Paige J. Bothwell, Brigid Conroy, Evgueni E. Nesterov, Irina V. Nesterova
Publikováno v:
ACS Sensors. 8:1109-1118
Publikováno v:
Canadian Journal of Chemistry. 100:18-24
Recent recognition of the soluble form of the amyloid-beta (Aβ) peptide as a neurotoxic agent in Alzheimer’s disease (AD) has spurred the development of agents to target this species. Because Aβ is known to chelate metal ions in solution, metal-b
Autor:
Gideon K. Yawson, Mark F. Will, Samantha E. Huffman, Evan T. Strandquist, Paige J. Bothwell, Ethan B. Oliver, C. Fiore Apuzzo, David C. Platt, Christopher S. Weitzel, Marjorie A. Jones, Gregory M. Ferrence, Christopher G. Hamaker, Michael I. Webb
Publikováno v:
Inorganic chemistry. 61(6)
Alzheimer's disease (AD) is a devastating neurological disorder for which soluble oligomers of the peptide amyloid-β (Aβ) are now recognized as the neurotoxic species. Metal-based therapeutics are uniquely suited to target Aβ, with ruthenium-based
Autor:
Marjorie A. Jones, David C. Platt, Samantha E. Huffman, Paige J. Bothwell, Samuel S. Fisher, Michael I. Webb, Gideon K. Yawson, Christopher G. Hamaker
Publikováno v:
Metallomics. 12:491-503
Alzheimer’s Disease (AD) is a devastating neurodegenerative disorder where one of the commonly observed pathological hallmarks is extracellular deposits of the peptide amyloid-β (Aβ). These deposits contain a high concentration of metals and init
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 7, p 2093 (2018)
Amino acid transporters alanine-serine-cysteine transporter 2 (ASCT2) and L-Type Amino Acid Transporter 1 (LAT1) are coordinately enhanced in human cancers where among other roles, they are thought to drive mechanistic target-of-rapamycin (mTOR) grow
Externí odkaz:
https://doaj.org/article/61e7eeb8f2524aaaa45a058b831bae5d
Autor:
Mark F. Will, Marjorie A. Jones, Brendan J. Wall, Gideon K. Yawson, Paige J. Bothwell, David C. Platt, Michael I. Webb, Gregory M. Ferrence, C. Fiore Apuzzo
Publikováno v:
Journal of medicinal chemistry. 64(14)
Alzheimer's disease (AD) is the most common form of dementia, where one of the pathological hallmarks of AD is extracellular protein deposits, the primary component of which is the peptide amyloid-β (Aβ). Recently, the soluble form of Aβ has been
Autor:
Samuel S. Fisher, Gideon K. Yawson, Paige J. Bothwell, Michael I. Webb, Christopher G. Hamaker, Samantha E. Huffman, David C. Platt, Gregory M. Ferrence, Marjorie A. Jones
Publikováno v:
Journal of Inorganic Biochemistry. 214:111303
Alzheimer's disease (AD) is the most common form of dementia, characterized by extracellular protein deposits, comprised primarily of the peptide amyloid-beta (Aβ), are a pathological indicator of the disease. Commonly known as Aβ plaques, these de
Autor:
A, Nuno, J M, Blumenthal, T J, Austin, J, Bothwell, G, Ebanks-Petrie, B J, Godley, A C, Broderick
Publikováno v:
Conservation biology : the journal of the Society for Conservation Biology. 32(2)
Unsustainable wildlife trade affects biodiversity and the livelihoods of communities dependent upon those resources. Wildlife farming has been proposed to promote sustainable trade, but characterizing markets and understanding consumer behavior remai
Autor:
M, Stewart, J, Bothwell, M, Rollins, C, Flanagan, MC, Stewart, T, Bourke, D, O'Donoghue, A, Bell, A, Burns, MD, Shields, Flannigan, Christopher, Bourke, Thomas, Sproule, Ashley, Terris, Mark, A, Sproule, C, Flannigan, J, McAloon, M, McGowan, L, Rooney, A, Ravel, M, McGinn, D, Graham, B, Maxwell, K, Keown, M, Terris
Publikováno v:
The Ulster Medical Journal
Publikováno v:
East African medical journal. 89(1)
Oculocutaneous albinism (OCA) is the most common inherited disorder in Southern African blacks and several types have been described. Molecular techniques, where available, can be used to confirm a clinical diagnosis and the type of OCA, if necessary