Zobrazeno 1 - 10
of 361
pro vyhledávání: '"J, Blumer"'
Autor:
Michael J. Blumer, Venkata A. Surapaneni, Jana Ciecierska-Holmes, Stefan Redl, Elisabeth J. Pechriggl, Frederik H. Mollen, Mason N. Dean
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
In animals, pigments but also nanostructures determine skin coloration, and many shades are produced by combining both mechanisms. Recently, we discovered a new mechanism for blue coloration in the ribbontail stingray Taeniura lymma, a species with e
Externí odkaz:
https://doaj.org/article/b1321b45107a4c508c9651a55c1236ea
Autor:
Andras T. Meszaros, Julia Hofmann, Madita L. Buch, Benno Cardini, Theresia Dunzendorfer-Matt, Florian Nardin, Michael J. Blumer, Margot Fodor, Martin Hermann, Bettina Zelger, Giorgi Otarashvili, Melanie Schartner, Annemarie Weissenbacher, Rupert Oberhuber, Thomas Resch, Jakob Troppmair, Dietmar ..fner, Heinz Zoller, Herbert Tilg, Erich Gnaiger, Theresa Hautz, Stefan Schneeberger
Publikováno v:
EBioMedicine, Vol 85, Iss , Pp 104311- (2022)
Summary: Background: Reliable biomarkers for organ quality assessment during normothermic machine perfusion (NMP) are desired. ATP (adenosine triphosphate) production by oxidative phosphorylation plays a crucial role in the bioenergetic homeostasis o
Externí odkaz:
https://doaj.org/article/e529ae879efe4ad79d300a1b0ac02665
Autor:
J. Oh, S. J. Matkovich, A. E. Riek, S. M. Bindom, J. S. Shao, R. D. Head, R. A. Barve, M. S. Sands, G. Carmeliet, P. Osei-Owusu, R. H. Knutsen, H. Zhang, K. J. Blumer, C. G. Nichols, R. P. Mecham, Á Baldán, B. A. Benitez, M. L. Sequeira-Lopez, R. A. Gomez, C. Bernal-Mizrachi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Myeloid cells are involved in hypertension, but their exact role in renin-induced hypertension remains unclear. Here the authors show that impaired vitamin D signaling in myeloid cells causes hypertension via macrophage-specific miR-106b-5p secretion
Externí odkaz:
https://doaj.org/article/8cb6617e470f45cba57e6e7e6d36d55d
Publikováno v:
European Journal of Organic Chemistry. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b577e4401f468c789089848271cebec
https://doi.org/10.1002/ejoc.202300365
https://doi.org/10.1002/ejoc.202300365
Autor:
Martin McMahon, Shannon J. Odelberg, Kendall J. Blumer, Michael D. Onken, Phaedra C. Ghazi, Donghan Shin, Jackson R. Richards, Conan G. Kinsey, Kali J. Dale, John Michael S. Sanchez, Michael T. Scherzer, Jae Hyuk Yoo, Amanda Truong
Galpha and MEK1/2 inhibition in combination with Baf A1 and CQ in MP41 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b62cecbbd58a39469827f70b19c5083
https://doi.org/10.1158/1078-0432.22476333
https://doi.org/10.1158/1078-0432.22476333
Autor:
Martin McMahon, Shannon J. Odelberg, Kendall J. Blumer, Michael D. Onken, Phaedra C. Ghazi, Donghan Shin, Jackson R. Richards, Conan G. Kinsey, Kali J. Dale, John Michael S. Sanchez, Michael T. Scherzer, Jae Hyuk Yoo, Amanda Truong
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435ae12189801037b26a40108d7bc033
https://doi.org/10.1158/1078-0432.22476306.v1
https://doi.org/10.1158/1078-0432.22476306.v1
Autor:
Martin McMahon, Shannon J. Odelberg, Kendall J. Blumer, Michael D. Onken, Phaedra C. Ghazi, Donghan Shin, Jackson R. Richards, Conan G. Kinsey, Kali J. Dale, John Michael S. Sanchez, Michael T. Scherzer, Jae Hyuk Yoo, Amanda Truong
Purpose:Mutational activation of GNAQ or GNA11 (GNAQ/11), detected in >90% of uveal melanomas, leads to constitutive activation of oncogenic pathways, including MAPK and YAP. To date, chemo- or pathway-targeted therapies, either alone or in combinati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e174ef9a4f492cc311540af6167f38
https://doi.org/10.1158/1078-0432.c.6529368
https://doi.org/10.1158/1078-0432.c.6529368
Publikováno v:
eLife, Vol 7 (2018)
Activation of heterotrimeric G proteins is a key step in many signaling cascades. However, a complete mechanism for this process, which requires allosteric communication between binding sites that are ~30 Å apart, remains elusive. We construct an at
Externí odkaz:
https://doaj.org/article/b702c1ac42d1476ca82226bd85919647
Autor:
Kevin D. Moeller, Kendall J. Blumer, Matthew R. Medcalf, Ruby L. Krueger, Zach T. Medcalf, Peter A. Rosston, Yu Zhu, Kevin M. Kaltenbronn
Publikováno v:
Synthesis (Stuttg)
The biological activity of natural products YM-254890 (YM) and FR900359 (FR) has led to significant interest in both their synthesis and the construction of more simplified analogs. While the simplified analogs lose much of the potency of the natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e32974a43d907392f34d8b43ec92d47
https://europepmc.org/articles/PMC9838186/
https://europepmc.org/articles/PMC9838186/
Publikováno v:
Molecular Biology of the Cell
Uveal melanomas (UMs) are malignant cancers arising from the pigmented layers of the eye. UM cells spread through the bloodstream, and circulating UM cells are detectable in patients before metastases appear. Extravasation of UM cells is necessary fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1885ca5c7a9d0c5d18ac655ffd44245b
http://europepmc.org/articles/PMC8098856
http://europepmc.org/articles/PMC8098856