Zobrazeno 1 - 10
of 84
pro vyhledávání: '"J, Bieblová"'
Publikováno v:
Plant and Soil. 167:149-155
Publikováno v:
Folia biologica. 51(1)
Utilization of vaccines generated by fusion of dendritic cells and tumour cells is a promising approach to tumour immunotherapy. We have examined the therapeutic efficacy of vaccines generated by fusion of HPV16-associated tumour cells TC-1 with syng
Publikováno v:
Folia biologica. 50(6)
We have investigated the capacity of cellular vaccines based on dendritic cells loaded with human HPV16 E6/E7 oncoprotein-derived peptides to induce immune responses in vitro and to elicit protective immunity in a murine experimental model mimicking
Publikováno v:
Folia biologica. 50(6)
Depletion of NK1.1+ cells by repeated i.p. injections of PK136 antibody significantly enhanced growth of MHC class I+ tumours in syngeneic mice. Depletion starting before tumour transplantation or on the day of transplantation substantially accelerat
Publikováno v:
Folia biologica. 49(6)
It has been demonstrated repeatedly that a high proportion of tumours derived from MHC class I+ precursors are MHC class I-. Since a major task in immunotherapy strategies for treatment of malignancies is to develop polyvalent tumour vaccines efficie
Publikováno v:
Folia biologica. 49(6)
It has been found previously that IL-2, IFNgamma and GM-CSF were capable of reducing the recurrence rate of HPV 16-associated tumours in mice with SMRTD. We were interested whether the therapeutic effect of the surgery and adjuvant cytokine treatment
Publikováno v:
Folia biologica. 49(5)
Hybridization of established dendritic cell lines with tumour cells represents a prospective technology for the construction of antitumour vaccines. Experiments were designed to examine whether administration of cell populations prepared by fusion of
Autor:
R, Mikysková, J, Bieblová, J, Símová, M, Indrová, T, Jandlová, V, Vonka, M, Smahel, J, Bubeník, L, Mendoza
Publikováno v:
Folia biologica. 49(1)
We have examined whether peritumoral administration of IFN-gamma can inhibit growth of HPV16-associated, MHC class I- tumour MK16/1/IIIABC (MK16) transplanted in syngeneic mice. It has been found that peritumoral administration of recombinant IFN-gam
Publikováno v:
Folia biologica. 48(6)
The aim of this paper was to assess whether the BMDC after freezing and thawing are capable to retain the immunophenotype and antigen-presenting capacity. BMDC were generated from bone marrow precursor cells as described previously by culturing the c
Autor:
L, Mendoza, J, Bubeník, J, Símová, J, Korb, J, Bieblová, V, Vonka, M, Indrová, R, Mikysková, T, Jandlová
Publikováno v:
Folia biologica. 48(3)
Experiments were designed to examine whether administration of APC at the site of HPV 16-associated tumours can inhibit tumour growth and whether the efficacy of established dendritic cell lines is comparable to that of fresh BMDC populations. Mice w