Soluble Urokinase Plasminogen Activator Receptor and Venous Thromboembolism in COVID‐19

Autor: Shengyuan Luo, Alexi Vasbinder, Jeanne M. Du‐Fay‐de‐Lavallaz, Joanne Michelle D. Gomez, Tisha Suboc, Elizabeth Anderson, Annika Tekumulla, Husam Shadid, Hanna Berlin, Michael Pan, Tariq U. Azam, Ibrahim Khaleel, Kishan Padalia, Chelsea Meloche, Patrick O'Hayer, Tonimarie Catalan, Pennelope Blakely, Christopher Launius, Kingsley‐Michael Amadi, Rodica Pop‐Busui, Sven H. Loosen, Athanasios Chalkias, Frank Tacke, Evangelos J. Giamarellos‐Bourboulis, Izzet Altintas, Jesper Eugen‐Olsen, Kim A. Williams, Annabelle Santos Volgman, Jochen Reiser, Salim S. Hayek

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 18 (2022)

Background Venous thromboembolism (VTE) contributes significantly to COVID‐19 morbidity and mortality. The urokinase receptor system is involved in the regulation of coagulation. Levels of soluble urokinase plasminogen activator receptor (suPAR) re

Externí odkaz: https://doaj.org/article/fced70faf2de433098fd1689f287ccf8

Development and validation of prognostic machine learning models for short- and long-term mortality among acutely hospitalized patients

Autor: Baker Jawad Jawad, Shakir Maytham Shaker, Izzet Altintas, Jesper Eugen-Olsen, Jan Nehlin, Ove Andersen, Thomas Kallemose

Background: Several scores predicting mortality at the emergency department have been developed. However, all with shortcomings either simple and applicable in a clinical setting, with poor performance, or advanced, with high performance, but clinica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::11a95baa95a773fc2de0e3b7d5a942e9
https://doi.org/10.21203/rs.3.rs-2722508/v1

suPAR Cut-Offs for Risk Stratification in Patients With Symptoms of COVID-19

Autor: Christian Rasmussen, Ove Andersen, Santeri Seppälä, Thomas Kallemose, Line Jee Hartmann Rasmussen, Jens Tingleff, Jan O. Nehlin, Sanaá Elmajdoubi, Izzet Altintas, Mette Bendtz Lindstrøm, Nora Olsen El Caidi, Harri Hyppölä, Klaus Tjelle Kristiansen, Marius Ahm Stauning, Jesper Eugen-Olsen, Hejdi Gamst-Jensen

Publikováno v: Biomarker Insights
Biomarker Insights, Vol 16 (2021)
Altintas, I, Eugen-Olsen, J, Seppälä, S, Tingleff, J, Stauning, M A, El Caidi, N O, Elmajdoubi, S, Gamst-Jensen, H, Lindstrøm, M B, Rasmussen, L J H, Kristiansen, K T, Rasmussen, C, Nehlin, J O, Kallemose, T, Hyppölä, H & Andersen, O 2021, ' suPAR Cut-Offs for Risk Stratification in Patients With Symptoms of COVID-19 ', Biomarker Insights, vol. 16, pp. 1-12 . https://doi.org/10.1177/11772719211034685

Objectives: Elevated soluble urokinase Plasminogen Activator Receptor (suPAR) is a biomarker associated with adverse outcomes. We aimed to investigate the associations between plasma suPAR levels (testing the cut-offs ⩽4, 4-6, and ⩾6 ng/mL) with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654574ad00defc92b174fb2b255d9d93
http://europepmc.org/articles/PMC8371731

Low levels of the prognostic biomarker suPAR are predictive of mild outcome in patients with symptoms of COVID-19 - a prospective cohort study

Autor: Mette Bendz Lindstroem, Thomas Kallemose, Izzet Altintas, Klaus Tjelle Kristiansen, Jesper Eugen-Olsen, Ove Andersen, Christian Rasmussen, Jens Tingleff, Jan O. Nehlin, Hejdi Gamst-Jensen, Marius Ahm Stauning, Line Jee Hartmann Rasmussen

OBJECTIVETo examine if baseline soluble urokinase plasminogen activator receptor (suPAR) can predict whether patients with COVID-19 symptoms will need mechanical ventilation during a 14-day follow-up. Furthermore, to examine differences in demographi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5dc2bb7ec823f8119da0f3e045c0ba
https://doi.org/10.1101/2020.05.27.20114678