Zobrazeno 1 - 10
of 256
pro vyhledávání: '"Izumi Nakashima"'
Publikováno v:
Journal of Tropical Life Science, Vol 1, Iss 1, Pp 9-16 (2010)
Paeoniflorin (PF), isolated from paeony root, has been used as a herbal medicine for more than 1200 years in China, Korea and Japan for its anti-allergic, anti-inflamatory and immunoregulatory effects. In this study, we found that PF induces apoptosi
Externí odkaz:
https://doaj.org/article/35df71a5865d4726b2cbf684a48f924d
Autor:
Ramachandra Rao Sathuluri, Yuji Takaoka, Shintaro Morisada, Keisuke Ohto, Wataru Iwasaki, Hidetaka Kawakita, Akari Kishida, Masaya Miyazaki, Izumi Nakashima
Publikováno v:
Journal of Applied Glycoscience
A spherical gel containing amino groups was prepared using monomers of N,N-dimethylacrylamide and N,N-dimethylaminoethyl methacrylate, with a cross-linker composed of N,N′-methylenebisacrylamide prepared by suspension polymerization for the adsorpt
Autor:
Kozue Takeda, Yoshiyuki Kawamoto, Haruhiko Suzuki, Ken-ichi Isobe, Izumi Nakashima, Masahide Takahashi, Yusuke Okuno, Masashi Kato
Publikováno v:
FEBS Letters. 580:839-843
The cysteine in the M/IXXCW motif is conserved in all but one (threonine in place of cysteine) of the human protein tyrosine kinases (PTKs). We showed that all RET-PTC-1 mutants in which the C in this motif (C376) was replaced with glycine, lysine, t
Autor:
Lasse R. Braathen, Masashi Kato, Joachim Weis, Claudio Vallan, V. von Felbert, Izumi Nakashima, F Córdoba, Jakob Weissenberger
Publikováno v:
Experimental Dermatology. 14:429-437
Photodynamic therapy (PDT) is widely used to treat preneoplastic skin lesions and non-melanoma skin tumours. Studies analyzing the effects of PDT on malignant melanoma have yielded conflicting results. On the one hand, melanoma cell lines in culture
Autor:
Francisco Córdoba, Masashi Kato, Izumi Nakashima, Verena von Felbert, Lasse R. Braathen, Joachim Weis, Claudio Vallan, Jakob Weissenberger
Publikováno v:
The American Journal of Pathology. 166:831-841
Interleukin (IL)-6 is a pleiotropic cytokine that has been shown to inhibit the growth of early stage and to promote the proliferation of advanced stage melanoma cells in vitro. In patients with metastasizing melanomas, highly increased IL-6 blood le
Autor:
Haruhiko Suzuki, Kozue Takeda, Yusuke Okuno, Izumi Nakashima, Masashi Kato, Yoshiyuki Kawamoto
Publikováno v:
Archives of Biochemistry and Biophysics. 434:3-10
Protein tyrosine kinases (PTKs) play key roles in starting the signal transduction network for cellular development and functions. A number of both receptor-type and non-receptor-type PTKs, which are normally at a resting state, are initially activat
Autor:
Takeshi Kobayashi, Yoko Nakahara, Kozue Takeda, Hiroyuki Honda, Masatake Fujioka, Izumi Nakashima, Akira Ito
Publikováno v:
Thermal Medicine(Japanese Journal of Hyperthermic Oncology). 21:139-149
Publikováno v:
European Journal of Immunology. 35:86-97
Naive T cells do not proliferate but remain alive in vivo. In contrast, naive T cells rapidly die in an in vitro culture, suggesting that some factors that are present at the sites of naive T cell circulation in vivo but missing in the bovine serum-c
Publikováno v:
The Journal of Experimental Medicine
Regulation of immune system is of paramount importance to prevent immune attacks against self-components. Mice deficient in the interleukin (IL)-2/IL-15 receptor β chain, CD122, are model animals of such immune attacks and characteristically have a
Publikováno v:
Immunology. 112:64-71
We previously developed a transgenic mouse line into which a rabbit protein kinase Calpha (PKCalpha) gene fused to a human CD2 promoter/enhancer was introduced, and we found that immunosenescence was facilitated in these transgenic mice. In this stud