Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Izuki Amano"'
Publikováno v:
Journal of Physiological Sciences, Vol 74, Iss 1, Pp 1-11 (2024)
Abstract Perfluorooctane sulfonate (PFOS) exerts adverse effects on neuronal development in young population. Limited evidences have shown that early-life PFOS exposure holds a potential risk for developing age-related neurodegenerative diseases such
Externí odkaz:
https://doaj.org/article/95cbef2c9c3842eba53e069cb7046cfd
Autor:
Hiraku Suzuki, Yuki Fujiwara, Winda Ariyani, Izuki Amano, Sumiyasu Ishii, Ayane Kate Ninomiya, Seiichi Sato, Akinori Takaoka, Noriyuki Koibuchi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4727 (2024)
Estrogen plays an important role in osteoporosis prevention. We herein report the possible novel signaling pathway of 17β-estradiol (E2) in the matrix mineralization of MC3T3-E1, an osteoblast-like cell line. In the culture media-containing stripped
Externí odkaz:
https://doaj.org/article/c8a0adddeffd4dc5afeca81b10f438d1
Autor:
Naoya Yamaguchi, Atsushi Suzuki, Aya Yoshida, Tatsushi Tanaka, Kohei Aoyama, Hisashi Oishi, Yuichiro Hara, Tomoo Ogi, Izuki Amano, Satomi Kameo, Noriyuki Koibuchi, Yasuhiro Shibata, Shinya Ugawa, Haruo Mizuno, Shinji Saitoh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract SLC26A4 is a known iodide transporter, and is localized at the apical membrane of thyrocytes. Previously, we reported that SLC26A7 is also involved in iodide transport and that Slc26a7 is a novel causative gene for congenital hypothyroidism.
Externí odkaz:
https://doaj.org/article/e96f5e5bc5174803af6db215698f5947
Autor:
Yuki Fujiwara, Yuhei Miyasaka, Ayane Ninomiya, Wataru Miyazaki, Toshiharu Iwasaki, Winda Ariyani, Izuki Amano, Noriyuki Koibuchi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12765 (2023)
Perfluorooctane sulfonate (PFOS) has been used in a wide variety of industrial and commercial products. The adverse effects of PFOS on the developing brain are becoming of a great concern. However, the molecular mechanisms of PFOS on brain developmen
Externí odkaz:
https://doaj.org/article/fcd33d67fba94195be97aec17f03b514
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 9011 (2023)
The nuclear estrogen receptor (ER) and G-protein-coupled ER (GPER1) play a crucial role during brain development and are involved in dendrite and spine growth as well as synapse formation. Soybean isoflavones, such as genistein, daidzein, and S-equol
Externí odkaz:
https://doaj.org/article/9b0f7eaf6cd94159adf07b2be15fb847
Publikováno v:
Endocrinology and Metabolism, Vol 36, Iss 4, Pp 703-716 (2021)
The proper organized expression of specific genes in time and space is responsible for the organogenesis of the central nervous system including the cerebellum. The epigenetic regulation of gene expression is tightly regulated by an intrinsic intrace
Externí odkaz:
https://doaj.org/article/b766f961cdeb49fc856255bf2520d911
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Activation and/or modulation of the membrane-associated receptors plays a critical role in brain development. Thyroid hormone (TH) acts on both nuclear receptors (thyroid hormone receptor, TR) and membrane-associated receptors, particularly integrin
Externí odkaz:
https://doaj.org/article/a6fe464ee91e45229eee2564925f48cb
Autor:
Hiroaki Shimizu, Yasuhiro Horibata, Izuki Amano, Megan J Ritter, Mariko Domae, Hiromi Ando, Hiroyuki Sugimoto, Ronald N Cohen, Anthony N Hollenberg
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0277830 (2022)
BackgroundSilencing Mediator of Retinoid and Thyroid hormone receptors (SMRT; NCoR2) is a transcriptional corepressor (CoR) which has been recognized as an important player in the regulation of hepatic lipogenesis and in somatic development in mouse
Externí odkaz:
https://doaj.org/article/2a8b2fc277ce4567bbe09f4ae2819cc4
Autor:
Megan J. Ritter, Izuki Amano, Norihiro Imai, Lorraine Soares De Oliveira, Kristen R. Vella, Anthony N. Hollenberg
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101315- (2021)
Objective: The nuclear receptor corepressor 1 (NCOR1) and the silencing mediator of retinoic acid and thyroid hormone (SMRT, also known as NCOR2) play critical and specific roles in nuclear receptor action. NCOR1, both in vitro and in vivo specifical
Externí odkaz:
https://doaj.org/article/c6a08cde21e64194991ac12dd7bb2084
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7869 (2022)
Perinatal hypothyroidism impairs cerebellar organogenesis and results in motor coordination defects. The thyroid hormone receptor binds to corepressor complexes containing histone deacetylase (HDAC) 3 in the absence of ligands and acts as a transcrip
Externí odkaz:
https://doaj.org/article/4c7477c3ac6c414098612c0845cb3a0a