Ultrasensitive allele inference from immune repertoire sequencing data with MiXCR.

Autor: Mikelov A; Stanford University; t.mikelov@gmail.com., Nefedev G; MiLaboratories Inc., Tashkeev A; University of Liege., Rodriguez OL; University of Louisville., Ortmans DA; University of Liege., Skatova V; MiLaboratories Inc., Izraelson M; MiLaboratories Inc., Davydov AN; MiLaboratories Inc, Central European Institute of Technology, Masaryk University., Poslavsky S; MiLaboratories Inc., Rahmouni S; University of Liege., Watson CT; University of Louisville., Chudakov DM; MiLaboratories Inc, Central European Institute of Technology, Masaryk University., Boyd SD; Stanford University., Bolotin DA; MiLaboratories Inc.

Publikováno v: Genome research [Genome Res] 2024 Oct 21. Date of Electronic Publication: 2024 Oct 21.

Targeted depletion of TRBV9 ⁺ T cells as immunotherapy in a patient with ankylosing spondylitis.

Autor: Britanova OV; Pirogov Russian National Research Medical University, Moscow, Russia.; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia., Lupyr KR; Pirogov Russian National Research Medical University, Moscow, Russia.; Skolkovo Institute of Science and Technology, Moscow, Russia., Staroverov DB; Pirogov Russian National Research Medical University, Moscow, Russia.; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia., Shagina IA; Pirogov Russian National Research Medical University, Moscow, Russia.; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia., Aleksandrov AA; BIOCAD, St. Petersburg, Russia., Ustyugov YY; BIOCAD, St. Petersburg, Russia., Somov DV; Pirogov Russian National Research Medical University, Moscow, Russia., Klimenko A; Pirogov Russian National Research Medical University, Moscow, Russia., Shostak NA; Pirogov Russian National Research Medical University, Moscow, Russia., Zvyagin IV; Pirogov Russian National Research Medical University, Moscow, Russia.; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia., Stepanov AV; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia., Merzlyak EM; Pirogov Russian National Research Medical University, Moscow, Russia.; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia., Davydov AN; Central European Institute of Technology, Masaryk University, Brno, Czech Republic.; MiLaboratories Inc., Sunnyvale, CA, USA., Izraelson M; MiLaboratories Inc., Sunnyvale, CA, USA., Egorov ES; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.; Miltenyi Biotec B.V. & Co. KG, Bergisch Gladbach, Germany., Bogdanova EA; Pirogov Russian National Research Medical University, Moscow, Russia., Vladimirova AK; BIOCAD, St. Petersburg, Russia., Iakovlev PA; BIOCAD, St. Petersburg, Russia., Fedorenko DA; Department of Hematology and Chemotherapy, Pirogov National Medical and Surgical Center, Moscow, Russia., Ivanov RA; BIOCAD, St. Petersburg, Russia., Skvortsova VI; Pirogov Russian National Research Medical University, Moscow, Russia.; Federal Medical Biological Agency, Moscow, Russia., Lukyanov S; Pirogov Russian National Research Medical University, Moscow, Russia.; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia., Chudakov DM; Pirogov Russian National Research Medical University, Moscow, Russia. chudakovdm@gmail.com.; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia. chudakovdm@gmail.com.; Central European Institute of Technology, Masaryk University, Brno, Czech Republic. chudakovdm@gmail.com.; Abu Dhabi Stem Cell Center, Al Muntazah, United Arab Emirates. chudakovdm@gmail.com.

Publikováno v: Nature medicine [Nat Med] 2023 Nov; Vol. 29 (11), pp. 2731-2736. Date of Electronic Publication: 2023 Oct 23.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Functionally specialized human CD4 ⁺ T-cell subsets express physicochemically distinct TCRs.

Autor: Kasatskaya SA; Center of Life Sciences, Skolkovo Institute of Science and Technology, Moscow, Russian Federation.; Genomics of Adaptive Immunity Department, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation., Ladell K; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom., Egorov ES; Genomics of Adaptive Immunity Department, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation., Miners KL; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom., Davydov AN; Adaptive Immunity Group, Central European Institute of Technology, Brno, Czech Republic., Metsger M; Adaptive Immunity Group, Central European Institute of Technology, Brno, Czech Republic., Staroverov DB; Genomics of Adaptive Immunity Department, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation.; Institute of Translational Medicine, Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, Moscow, Russian Federation., Matveyshina EK; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russian Federation., Shagina IA; Genomics of Adaptive Immunity Department, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation.; Institute of Translational Medicine, Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, Moscow, Russian Federation., Mamedov IZ; Genomics of Adaptive Immunity Department, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation.; Institute of Translational Medicine, Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, Moscow, Russian Federation., Izraelson M; Genomics of Adaptive Immunity Department, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation.; Institute of Translational Medicine, Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, Moscow, Russian Federation., Shelyakin PV; Center of Life Sciences, Skolkovo Institute of Science and Technology, Moscow, Russian Federation.; Genomics of Adaptive Immunity Department, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation., Britanova OV; Genomics of Adaptive Immunity Department, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation.; Institute of Translational Medicine, Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, Moscow, Russian Federation., Price DA; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom.; Systems Immunity Research Institute, Cardiff University School of Medicine, Cardiff, United Kingdom., Chudakov DM; Center of Life Sciences, Skolkovo Institute of Science and Technology, Moscow, Russian Federation.; Genomics of Adaptive Immunity Department, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation.; Institute of Translational Medicine, Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, Moscow, Russian Federation.

Publikováno v: ELife [Elife] 2020 Dec 08; Vol. 9. Date of Electronic Publication: 2020 Dec 08.

Measuring Intratumoral Heterogeneity of Immune Repertoires.

Autor: Yuzhakova DV; Laboratory of Genomics of Antitumor Adaptive Immunity, Privolzhsky Research Medical University, Nizhny Novgorod, Russia., Volchkova LN; Laboratory of Genomics of Antitumor Adaptive Immunity, Privolzhsky Research Medical University, Nizhny Novgorod, Russia., Pogorelyy MV; Genomics of Adaptive Immunity Department, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.; Department of Molecular Technologies, Institute of Translational Medicine, Pirogov Russian National Research Medical University, Moscow, Russia., Serebrovskaya EO; Genomics of Adaptive Immunity Department, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.; Department of Molecular Technologies, Institute of Translational Medicine, Pirogov Russian National Research Medical University, Moscow, Russia., Shagina IA; Genomics of Adaptive Immunity Department, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.; Department of Molecular Technologies, Institute of Translational Medicine, Pirogov Russian National Research Medical University, Moscow, Russia., Bryushkova EA; Department of Molecular Technologies, Institute of Translational Medicine, Pirogov Russian National Research Medical University, Moscow, Russia.; Department of Molecular Biology, Moscow State University, Moscow, Russia., Nakonechnaya TO; Laboratory of Genomics of Antitumor Adaptive Immunity, Privolzhsky Research Medical University, Nizhny Novgorod, Russia.; Genomics of Adaptive Immunity Department, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.; Department of Molecular Technologies, Institute of Translational Medicine, Pirogov Russian National Research Medical University, Moscow, Russia., Izosimova AV; Laboratory of Genomics of Antitumor Adaptive Immunity, Privolzhsky Research Medical University, Nizhny Novgorod, Russia., Zavyalova DS; Laboratory of Genomics of Antitumor Adaptive Immunity, Privolzhsky Research Medical University, Nizhny Novgorod, Russia., Karabut MM; Laboratory of Genomics of Antitumor Adaptive Immunity, Privolzhsky Research Medical University, Nizhny Novgorod, Russia., Izraelson M; Laboratory of Genomics of Antitumor Adaptive Immunity, Privolzhsky Research Medical University, Nizhny Novgorod, Russia.; Genomics of Adaptive Immunity Department, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.; Department of Molecular Technologies, Institute of Translational Medicine, Pirogov Russian National Research Medical University, Moscow, Russia., Samoylenko IV; Oncodermatology Department, N. N. Blokhin Russian Cancer Research Center, Moscow, Russia., Zagainov VE; Laboratory of Genomics of Antitumor Adaptive Immunity, Privolzhsky Research Medical University, Nizhny Novgorod, Russia.; Volga District Medical Centre Under Federal Medical and Biological Agency, Nizhny Novgorod, Russia., Chudakov DM; Laboratory of Genomics of Antitumor Adaptive Immunity, Privolzhsky Research Medical University, Nizhny Novgorod, Russia.; Genomics of Adaptive Immunity Department, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.; Department of Molecular Technologies, Institute of Translational Medicine, Pirogov Russian National Research Medical University, Moscow, Russia.; Adaptive Immunity Group, Central European Institute of Technology, Masaryk University, Brno, Czechia.; MiLaboratory LLC, Skolkovo Innovation Centre, Moscow, Russia., Zagaynova EV; Laboratory of Genomics of Antitumor Adaptive Immunity, Privolzhsky Research Medical University, Nizhny Novgorod, Russia., Sharonov GV; Laboratory of Genomics of Antitumor Adaptive Immunity, Privolzhsky Research Medical University, Nizhny Novgorod, Russia.; Genomics of Adaptive Immunity Department, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.; Department of Molecular Technologies, Institute of Translational Medicine, Pirogov Russian National Research Medical University, Moscow, Russia.

Publikováno v: Frontiers in oncology [Front Oncol] 2020 May 08; Vol. 10, pp. 512. Date of Electronic Publication: 2020 May 08 (Print Publication: 2020).