DNA methylome in visceral adipose tissue can discriminate patients with and without colorectal cancer

Autor: Izquierdo AG, Boughanem H, Diaz-Lagares A, Arranz-Salas I, Esteller M, Tinahones FJ, Casanueva FF, Macias-Gonzalez M, Crujeiras AB

Publikováno v: Epigenetics
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname

Adipose tissue dysfunction, particularly the visceral (VAT) compartment, has been proposed to play a relevant role in colorectal cancer (CRC) development and progression. Epigenetic mechanisms could be involved in this association. The current study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::8081a35de9cdd4c495f94d8a1627c8d1
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=5076

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

ZNF577 Methylation Levels in Leukocytes From Women With Breast Cancer Is Modulated by Adiposity, Menopausal State, and the Mediterranean Diet

Autor: Paula M. Lorenzo, Andrea G. Izquierdo, Angel Diaz-Lagares, Marcos C. Carreira, Manuel Macias-Gonzalez, Juan Sandoval, Juan Cueva, Rafael Lopez-Lopez, Felipe F. Casanueva, Ana B. Crujeiras

Publikováno v: Frontiers in Endocrinology
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Frontiers in Endocrinology, Vol 11 (2020)

The methylation levels of ZNF577 in breast tumors has been previously identified as a possible epigenetic mark of breast cancer associated with obesity. The aim of the current study was to investigate differences in methylation levels of ZNF577 depen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb60082f13ed60d8dfada124c8b898a
https://hdl.handle.net/10668/15539

Author Correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk.

Autor: Shrine N; Department of Population Health Sciences, University of Leicester, Leicester, UK. nick.shrine@leicester.ac.uk., Izquierdo AG; Department of Population Health Sciences, University of Leicester, Leicester, UK., Chen J; Department of Population Health Sciences, University of Leicester, Leicester, UK., Packer R; Department of Population Health Sciences, University of Leicester, Leicester, UK., Hall RJ; Division of Respiratory Medicine and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Guyatt AL; Department of Population Health Sciences, University of Leicester, Leicester, UK., Batini C; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Thompson RJ; Division of Respiratory Medicine and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Pavuluri C; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Malik V; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Hobbs BD; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Moll M; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Kim W; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Tal-Singer R; COPD Foundation, Washington DC, USA., Bakke P; Department of Clinical Science, Unversity of Bergen, Bergen, Norway., Fawcett KA; Department of Population Health Sciences, University of Leicester, Leicester, UK., John C; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Coley K; Department of Population Health Sciences, University of Leicester, Leicester, UK., Piga NN; Department of Population Health Sciences, University of Leicester, Leicester, UK., Pozarickij A; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Lin K; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Millwood IY; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, University of Oxford, Oxford, UK., Chen Z; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, University of Oxford, Oxford, UK., Li L; Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China., Wijnant SRA; Department of Respiratory Diseases, Ghent Universital Hospital, Ghent, Belgium.; Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.; Department of Epidemiology, Eramus Medical Center, Rotterdam, The Netherlands., Lahousse L; Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.; Department of Epidemiology, Eramus Medical Center, Rotterdam, The Netherlands., Brusselle G; Department of Respiratory Diseases, Ghent Universital Hospital, Ghent, Belgium.; Department of Epidemiology, Eramus Medical Center, Rotterdam, The Netherlands., Uitterlinden AG; Department of Internal Medicine, Eramus Medical Center, Rotterdam, The Netherlands., Manichaikul A; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Oelsner EC; Department of Medicine, Columbia University Medical Center, New York, NY, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Barr RG; Department of Medicine, Columbia University Medical Center, New York, NY, USA., Kerr SM; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Vitart V; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Brown MR; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Wielscher M; MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Imboden M; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; Department of Public Health, University of Basel, Basel, Switzerland., Jeong A; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; Department of Public Health, University of Basel, Basel, Switzerland., Bartz TM; Cardiovascular Health Research Unit, Departments of Medicine and Biostatistics, University of Washington, Seattle, WA, USA., Gharib SA; Computational Medicine Core, Center for Lung Biology, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA, USA., Flexeder C; Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Munich, Germany.; Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), Munich, Germany.; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Karrasch S; Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Munich, Germany.; Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), Munich, Germany.; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Gieger C; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Peters A; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute for Medical Information Processing, Biometry and Epidemiology, Medical Faculty, Ludwig Maximilian University, Munich, Germany., Stubbe B; Department of Internal Medicine B-Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Greifswald, Germany., Hu X; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Ortega VE; Division of Respiratory Medicine, Department of Internal Medicine, Center for Individualized Medicine, Mayo Clinic, Scottsdale, AZ, USA., Meyers DA; Department of Medicine, University of Arizona, Tucson, AZ, USA., Bleecker ER; Department of Medicine, University of Arizona, Tucson, AZ, USA., Gabriel SB; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Gupta N; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Smith AV; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Luan J; MRC Epidemiology Unit, Institute of Metabolic Science, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Zhao JH; Department of Public and Primary Care, Heart and Lung Research Institute, University of Cambridge, Cambridge, UK., Hansen AF; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU Norwegian University of Science and Technology, Trondheim, Norway., Langhammer A; HUNT Research Centre, Department of Public Health and Nursing, NTNU Norwegian University of Science and Technology, Levanger, Norway.; Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway., Willer C; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Bhatta L; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU Norwegian University of Science and Technology, Trondheim, Norway., Porteous D; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Smith BH; Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Campbell A; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Sofer T; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Lee J; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA., Daviglus ML; Institute for Minority Health Research, University of Illinois at Chicago, Chicago, IL, USA., Yu B; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Lim E; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA., Xu H; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA., O'Connor GT; Pulmonary Center, School of Medicine, Boston University, Boston, MA, USA., Thareja G; Bioinformatics Core, Weill Cornell Medicine-Qatar, Education City, Doha, Qatar., Albagha OME; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar.; Center for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Suhre K; Bioinformatics Core, Weill Cornell Medicine-Qatar, Education City, Doha, Qatar.; Department of Biophysics and Physiology, Weill Cornell Medicine, New York, NY, USA., Granell R; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Faquih TO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Hiemstra PS; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands., Slats AM; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands., Mullin BH; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; School of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia., Hui J; Busselton Population Medical Research Institute, QEII Medical Centre, Nedlands, Western Australia, Australia.; School of Population and Global Health, University of Western Australia, Crawley, Western Australia, Australia.; PathWest Laboratory Medicine of WA, Nedlands, Western Australia, Australia., James A; Busselton Population Medical Research Institute, QEII Medical Centre, Nedlands, Western Australia, Australia., Beilby J; School of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia.; Busselton Population Medical Research Institute, QEII Medical Centre, Nedlands, Western Australia, Australia., Patasova K; Department of Twin Research and Genetic Epidemiology, King's College London School of Medicine, London, UK.; Division of Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden., Hysi P; Department of Twin Research and Genetic Epidemiology, King's College London School of Medicine, London, UK.; UCL Institute of Ophthalmology, University College London, London, UK., Koskela JT; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Wyss AB; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA., Jin J; Westat, Durham, NC, USA., Sikdar S; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA.; Department of Mathematics and Statistics, Old Dominion University, Norfolk, VA, USA., Lee M; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA., May-Wilson S; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Pirastu N; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Kentistou KA; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Joshi PK; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Timmers PRHJ; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Williams AT; Department of Population Health Sciences, University of Leicester, Leicester, UK., Free RC; Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK.; Department of Respiratory Sciences, University of Leicester, Leicester, UK., Wang X; Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK.; Department of Respiratory Sciences, University of Leicester, Leicester, UK., Morrison JL; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Gilliland FD; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Chen Z; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Wang CA; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, New South Wales, Australia.; Hunter Medical Research Institute, Newcastle, New South Wales, Australia., Foong RE; Wal-yan Respiratory Research Centre, Telethon Kids Institute, Perth, Western Australia, Australia.; School of Allied Health, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia., Harris SE; Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK., Taylor A; Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK., Redmond P; Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK., Cook JP; Department of Health Data Science, University of Liverpool, Liverpool, UK., Mahajan A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Genentech, South San Francisco, CA, USA., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Palviainen T; Institute for Molecular Medicine Finland-FIMM, University of Helsinki, Helsinki, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Kaprio J; Institute for Molecular Medicine Finland-FIMM, University of Helsinki, Helsinki, Finland., Rantanen T; Faculty of Sport and Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland., Pietiläinen KH; Obesity Research Unit, Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Obesity and Abdominal Centers, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Cox SR; Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK., Pennell CE; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, New South Wales, Australia.; Hunter Medical Research Institute, Newcastle, New South Wales, Australia.; Department of Maternity and Gynaecology, John Hunter Hospital, Newcastle, New South Wales, Australia., Hall GL; Wal-yan Respiratory Research Centre, Telethon Kids Institute, Perth, Western Australia, Australia.; School of Allied Health, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia., Gauderman WJ; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Brightling C; Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK.; Department of Infection, Inflammation and Immunity, Institute for Lung Health, University of Leicester, Leicester, UK., Wilson JF; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK., Vasankari T; FILHA-Finnish Lung Health Association, Helsinki, Finland.; Department of Respiratory Diseases and Allergology, University of Turku, Turku, Finland., Laitinen T; Administration Center, Tampere University Hospital and University of Tampere, Tampere, Finland., Salomaa V; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands., Timpson NJ; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; ALSPAC, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Zeggini E; Wellcome Sanger Institute, Cambridge, UK.; Institute of Translational Genomics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Technical University of Munich (TUM) and Klinikum Rechts der Isar, TUM School of Medicine, Munich, Germany., Dupuis J; Department of Epidemiology, Biostatistics, and Occupational Health, School of Population and Global Health, McGill University, Montreal, Quebec, Canada., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Brumpton B; HUNT Research Centre, Department of Public Health and Nursing, NTNU Norwegian University of Science and Technology, Levanger, Norway.; Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, School of Clinical Medicine, University of Cambridge, Cambridge, UK.; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK.; Computational Medicine, Berlin Institute of Health at Charité, Universitätsmedizin Berlin, Berlin, Germany., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Schmidt CO; Institute for Community Medicine, SHIP-Clinical Epidemiological Research, University Medicine Greifswald, Greifswald, Germany., Probst-Hensch N; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; Department of Public Health, University of Basel, Basel, Switzerland., Jarvelin MR; MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Unit of Primary Health Care, Oulu University Hospital, OYS, Oulu, Finland., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Polasek O; School of Medicine, University of Split, Split, Croatia., Rudan I; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK., Lee JH; Jeffrey Cheah Biomedical Centre, Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Sayers I; Division of Respiratory Medicine and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Rawlins EL; Wellcome Trust-CRUK Gurdon Institute and Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Dudbridge F; Department of Population Health Sciences, University of Leicester, Leicester, UK., Silverman EK; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Strachan DP; Population Health Research Institute, St George's University of London, London, UK., Walters RG; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, University of Oxford, Oxford, UK., Morris AP; Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK., London SJ; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA., Cho MH; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Wain LV; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Hall IP; Division of Respiratory Medicine and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Tobin MD; Department of Population Health Sciences, University of Leicester, Leicester, UK. martin.tobin@leicester.ac.uk.; Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK. martin.tobin@leicester.ac.uk.

Publikováno v: Nature genetics [Nat Genet] 2023 Oct; Vol. 55 (10), pp. 1778-1779.

Gender Dimorphism in Hepatic Carcinogenesis-Related Gene Expression Associated with Obesity as a Low-Grade Chronic Inflammatory Disease.

Autor: Izquierdo AG; Epigenomics in Endocrinology and Nutrition Group, Epigenomics Unit, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela (CHUS/SERGAS), 15706 Santiago de Compostela, Spain., Carreira MC; CIBER Fisiopatologia de la Obesidad y Nutricion (CIBERobn), 28029 Madrid, Spain.; Molecular Endocrinology Group, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela (CHUS/SERGAS), 15706 Santiago de Compostela, Spain., Rodriguez-Carnero G; Epigenomics in Endocrinology and Nutrition Group, Epigenomics Unit, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela (CHUS/SERGAS), 15706 Santiago de Compostela, Spain.; Division of Endocrinology and Nutrition, Complejo Hospitalario Universitario de Santiago de Compostela (CHUS/SERGAS), 15706 Santiago de Compostela, Spain., Perez-Lois R; Endocrine Physiopathology Group, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela (CHUS/SERGAS), 15706 Santiago de Compostela, Spain., Seoane LM; CIBER Fisiopatologia de la Obesidad y Nutricion (CIBERobn), 28029 Madrid, Spain.; Endocrine Physiopathology Group, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela (CHUS/SERGAS), 15706 Santiago de Compostela, Spain., Casanueva FF; CIBER Fisiopatologia de la Obesidad y Nutricion (CIBERobn), 28029 Madrid, Spain.; Molecular Endocrinology Group, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela (CHUS/SERGAS), 15706 Santiago de Compostela, Spain., Crujeiras AB; Epigenomics in Endocrinology and Nutrition Group, Epigenomics Unit, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela (CHUS/SERGAS), 15706 Santiago de Compostela, Spain.; CIBER Fisiopatologia de la Obesidad y Nutricion (CIBERobn), 28029 Madrid, Spain.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 30; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 30.