Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Izortze, Santin"'
Autor:
Aina Lluch, Jèssica Latorre, Núria Oliveras-Cañellas, Ana Fernández-Sánchez, José M. Moreno-Navarrete, Anna Castells-Nobau, Ferran Comas, Maria Buxò, José I. Rodríguez-Hermosa, María Ballester, Isabel Espadas, Alejandro Martín-Montalvo, Birong Zhang, You Zhou, Ralph Burkhardt, Marcus Höring, Gerhard Liebisch, Ainara Castellanos-Rubio, Izortze Santin, Asha Kar, Markku Laakso, Päivi Pajukanta, Vesa M. Olkkonen, José M. Fernández-Real, Francisco J. Ortega
Publikováno v:
Molecular Metabolism, Vol 90, Iss , Pp 102040- (2024)
Background: Long non-coding RNAs (lncRNAs) can perform tasks of key relevance in fat cells, contributing, when defective, to the burden of obesity and its sequelae. Here, scrutiny of adipose tissue transcriptomes before and after bariatric surgery (G
Externí odkaz:
https://doaj.org/article/ca620d31a1364335831107541b0e2f56
Autor:
Ane Olazagoitia‐Garmendia, Henar Rojas‐Márquez, Maialen Sebastian‐delaCruz, Aloña Agirre‐Lizaso, Anne Ochoa, Luis Manuel Mendoza‐Gomez, Maria J Perugorria, Luis Bujanda, Alain Huerta Madrigal, Izortze Santin, Ainara Castellanos‐Rubio
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Cytokine mediated sustained inflammation increases the risk to develop different complex chronic inflammatory diseases, but the implicated mechanisms remain unclear. Increasing evidence shows that long noncoding RNAs (lncRNAs) play key roles
Externí odkaz:
https://doaj.org/article/2f41a2bb7e6d45ddbe55bfb28e891916
Autor:
Itziar González‐Moro, Koldo Garcia‐Etxebarria, Luis Manuel Mendoza, Nora Fernández‐Jiménez, Jon Mentxaka, Ane Olazagoitia‐Garmendia, María Nicol Arroyo, Toshiaki Sawatani, Cristina Moreno‐Castro, Chiara Vinci, Anne Op de Beek, Miriam Cnop, Mariana Igoillo‐Esteve, Izortze Santin
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Type 1 diabetes (T1D) is a complex autoimmune disease that develops in genetically susceptible individuals. Most T1D‐associated single nucleotide polymorphisms (SNPs) are located in non‐coding regions of the human genome. Interestingly,
Externí odkaz:
https://doaj.org/article/e0b08b72f8934629b39760d37febee3a
Autor:
Itziar González-Moro, Henar Rojas-Márquez, Maialen Sebastian-delaCruz, Jon Mentxaka-Salgado, Ane Olazagoitia-Garmendia, Luis Manuel Mendoza, Aina Lluch, Federica Fantuzzi, Carmen Lambert, Jessica Ares Blanco, Lorella Marselli, Piero Marchetti, Miriam Cnop, Elías Delgado, José Manuel Fernández-Real, Francisco José Ortega, Ainara Castellanos-Rubio, Izortze Santin
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionMost of the disease-associated single nucleotide polymorphisms (SNPs) lie in non- coding regions of the human genome. Many of these variants have been predicted to impact the expression and function of long non-coding RNAs (lncRNA), but t
Externí odkaz:
https://doaj.org/article/ebe17607831f49a7867679d95c1d4143
Autor:
Amaia Jauregi-Miguel, Izortze Santin, Koldo Garcia-Etxebarria, Ane Olazagoitia-Garmendia, Irati Romero-Garmendia, Maialen Sebastian-delaCruz, Iñaki Irastorza, Spanish Consortium for the Genetics of Celiac Disease, Ainara Castellanos-Rubio, Jose Ramón Bilbao
Publikováno v:
Frontiers in Nutrition, Vol 6 (2019)
Celiac disease (CD) patients present a loss of intestinal barrier function due to structural alterations in the tight junction (TJ) network, the most apical unions between epithelial cells. The association of TJ-related gene variants points to an imp
Externí odkaz:
https://doaj.org/article/59193204e3404c659d3ab3fdb52d1104
Autor:
Maialen Sebastian-delaCruz, Itziar Gonzalez-Moro, Ane Olazagoitia-Garmendia, Ainara Castellanos-Rubio, Izortze Santin
Publikováno v:
Non-Coding RNA, Vol 7, Iss 1, p 3 (2021)
mRNA stability influences gene expression and translation in almost all living organisms, and the levels of mRNA molecules in the cell are determined by a balance between production and decay. Maintaining an accurate balance is crucial for the correc
Externí odkaz:
https://doaj.org/article/40ee4a585dfc42bfaa83552da6dc5a2b
Autor:
Maialen Sebastian-delaCruz, Ane Olazagoitia-Garmendia, Itziar Gonzalez-Moro, Izortze Santin, Koldo Garcia-Etxebarria, Ainara Castellanos-Rubio
Publikováno v:
Epigenomes, Vol 4, Iss 3, p 16 (2020)
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal tract that develops due to the interaction between genetic and environmental factors. More than 160 loci have been associated with IBD, but the functional im
Externí odkaz:
https://doaj.org/article/4e7460e68bb64b5fb984cc8a10dc1610
Autor:
Itziar González-Moro, Koldo Garcia-Etxebarria, Luis Manuel Mendoza, Nora Fernández-Jiménez, Jon Mentxaka-Salgado, Ane Olazagoitia-Garmendia, María Nicol Arroyo, Toshiaki Sawatani, Anne Op de Beek, Miriam Cnop, Mariana Igoillo-Esteve, Izortze Santin
SummaryType 1 diabetes-associated single nucleotide polymorphisms are mainly located in non-coding regions of the human genome. Single nucleotide polymorphisms located in long non-coding RNAs may result in the disruption of their secondary structure,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed04dc76b7bd0a247bac8f6027de8f5e
https://doi.org/10.1101/2022.12.01.518685
https://doi.org/10.1101/2022.12.01.518685
Autor:
Luis Manuel Mendoza-Gomez, Maialen Sebastian-delaCruz, Ane Olazagoitia-Garmendia, Itziar González-Moro, Henar Rojas-Márquez, Jon Mentxaka, Izortze Santin, Ainara Castellanos-Rubio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a57fb3ca6ebff5560f7226614bdfb2f
https://doi.org/10.1016/bs.mcb.2022.11.005
https://doi.org/10.1016/bs.mcb.2022.11.005