Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Izna, Ali"'
Autor:
Michael C. Snabes, M.D., Ph.D., Juki Ng, Pharm.D., Ph.D., Hong Li, Ph.D., Izna Ali, Pharm.D., Ph.D., Mohamad Shebley, Ph.D., William D. Schlaff, M.D
Publikováno v:
F&S Reports, Vol 4, Iss 2, Pp 206-212 (2023)
Objective: Evaluate the efficacy and safety of elagolix, a GnRH antagonist, to treat polycystic ovarian syndrome (PCOS). Design: A phase 2, multicenter, double-blind, randomized, placebo-controlled trial. Setting: Outpatient and academic medical cent
Externí odkaz:
https://doaj.org/article/697c3f78e0a74cedbb22beaee3ff80f7
Autor:
Mohamad Shebley, Stanley Wang, Izna Ali, Preethi Krishnan, Rakesh Tripathi, Joseph M. Reardon, John Cafardi, Galia Rahav, Yoseph Caraco, Jihad Slim, Fadi Al Akhrass, Mengjia Yu, Yiran Hu, Rosa De Abreu Ferreira, Negar N. Alami
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 1, Pp n/a-n/a (2023)
Abstract ABBV‐47D11 is a neutralizing monoclonal antibody that targets a mutationally conserved hydrophobic pocket distal to the ACE2 binding site of SARS‐CoV‐2. This first‐in‐human safety, pharmacokinetics, and antiviral pharmacodynamic as
Externí odkaz:
https://doaj.org/article/1ec46728fbc04f62a659f561489d4b07
Autor:
Mohamad Shebley, Stanley Wang, Izna Ali, Preethi Krishnan, Rakesh Tripathi, Joseph M. Reardon, John Cafardi, Galia Rahav, Yoseph Caraco, Jihad Slim, Fadi Al Akhrass, Mengjia Yu, Yiran Hu, Rosa De Abreu Ferreira, Negar N. Alami
Publikováno v:
Pharmacology Research & Perspectives. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::845510e3de7301902bc2085045e754f2
https://doi.org/10.1002/prp2.1036
https://doi.org/10.1002/prp2.1036
Autor:
Mohamad, Shebley, Stanley, Wang, Izna, Ali, Preethi, Krishnan, Rakesh, Tripathi, Joseph M, Reardon, John, Cafardi, Galia, Rahav, Yoseph, Caraco, Jihad, Slim, Fadi, Al Akhrass, Mengjia, Yu, Yiran, Hu, Rosa De Abreu, Ferreira, Negar N, Alami
Publikováno v:
Pharmacology researchperspectivesREFERENCES. 11(1)
ABBV-47D11 is a neutralizing monoclonal antibody that targets a mutationally conserved hydrophobic pocket distal to the ACE2 binding site of SARS-CoV-2. This first-in-human safety, pharmacokinetics, and antiviral pharmacodynamic assessment in patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7efe048bc5e78f8b29de9295f93365ad
https://pubmed.ncbi.nlm.nih.gov/36537346
https://pubmed.ncbi.nlm.nih.gov/36537346
Autor:
Kotaro Omori, Joseph A. Nicolazzo, Yijun Pan, Masanori Tachikawa, Kim L. R. Brouwer, Tetsuya Terasaki, Izna Ali
Publikováno v:
J Pharm Sci
It is well established that the expression and function of drug transporters at the blood-brain barrier are altered in Alzheimer's disease (AD). However, we recently demonstrated in a mouse model of AD that the expression of key drug transporters and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d691a705ecb3ce9103e7f642cd3a3de
https://doi.org/10.1016/j.xphs.2019.02.016
https://doi.org/10.1016/j.xphs.2019.02.016
Autor:
Kotaro Omori, Masanori Tachikawa, Kim L. R. Brouwer, Tetsuya Terasaki, Joseph A. Nicolazzo, Yijun Pan, Izna Ali
Publikováno v:
Molecular Pharmaceutics. 18:3928-3929
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e9e05cc91de27aed7361b5f2b9adcc9
https://doi.org/10.1021/acs.molpharmaceut.1c00661
https://doi.org/10.1021/acs.molpharmaceut.1c00661
Publikováno v:
Molecular pharmaceutics. 16(3)
The bile salt export pump (BSEP) is the primary canalicular transporter responsible for the secretion of bile acids from hepatocytes into bile canaliculi, and inhibition of this transporter has been associated with drug-induced liver injury (DILI). A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f843f9d4f3ca1ac703bc6379dd9cf66
https://pubmed.ncbi.nlm.nih.gov/30608704
https://pubmed.ncbi.nlm.nih.gov/30608704
Publikováno v:
Br J Clin Pharmacol
Aims Patients with Alzheimer's disease (AD), the most common form of dementia, have reduced P-glycoprotein (P-gp) function at the blood-brain barrier. However, the effect of AD on P-gp function in peripheral organs, and the impact on medication effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e645314b5ae1f9af5ef87d0e57f059ba
https://pubmed.ncbi.nlm.nih.gov/31269278
https://pubmed.ncbi.nlm.nih.gov/31269278
Autor:
Masanori Tachikawa, Kotaro Omori, Izna Ali, Tetsuya Terasaki, Yijun Pan, Kim L. R. Brouwer, Joseph A. Nicolazzo
Publikováno v:
Molecular pharmaceutics. 15(9)
Drug transporter expression and function at the blood-brain barrier is altered in Alzheimer's disease (AD). However, the impact of AD on the expression of transporters and metabolizing enzymes in peripheral tissues has received little attention. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f3afd6f9d276ceb45de7c1045670c4
https://pubmed.ncbi.nlm.nih.gov/34478315
https://pubmed.ncbi.nlm.nih.gov/34478315
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::108e6e2f8a232cd2fa9adabe112238fa
https://doi.org/10.1016/j.jalz.2018.06.1907
https://doi.org/10.1016/j.jalz.2018.06.1907