Výsledky vyhledávání - "Izael de Sousa Costa"

Akademický článek

Biochemical characterisation of a Kunitz-type inhibitor from Tamarindus indica L. seeds and its efficacy in reducing plasma leptin in an experimental model of obesity

Autor: Amanda Fernandes de Medeiros, Izael de Sousa Costa, Fabiana Maria Coimbra de Carvalho, Sumika Kiyota, Beatriz Blenda Pinheiro de Souza, Daniel Nogoceke Sifuentes, Raphael Paschoal Serquiz, Bruna Leal Lima Maciel, Adriana Ferreira Uchôa, Elizeu Antunes dos Santos, Ana Heloneida de Araújo Morais

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 334-348 (2018)

A trypsin inhibitor isolated from tamarind seed (TTI) has satietogenic effects in animals, increasing the cholecystokinin (CCK) in eutrophy and reducing leptin in obesity. We purified TTI (pTTI), characterised, and observed its effect upon CCK and le

Externí odkaz: https://doaj.org/article/bf10a091414d47a9a9f8b24c94232dd2

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Insulin-Like Proteins in Plant Sources: A Systematic Review

Autor: Amanda Fernandes de Medeiros, Grasiela Piuvezam, Izael de Sousa Costa, Ana Heloneida A Morais Morais, Gidyenne Cbs Medeiros, Bruna Ll Maciel

Publikováno v: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 13:3421-3431

Type 2 diabetes mellitus (T2DM) is characterized by hyperglycemia. Proteins in plant sources that enable the maintenance of the glycemic profile may be of interest in the context of T2DM. However, their mechanisms of action are unclear, unlike other

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77135c9cb057e9f026c001a16bfe8c45
https://doi.org/10.2147/dmso.s256883

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Beneficial Effects of Tamarind Trypsin Inhibitor in Chitosan–Whey Protein Nanoparticles on Hepatic Injury Induced High Glycemic Index Diet: A Preclinical Study

Autor: Izael de Sousa Costa, Alexandre C. Serquiz, Gerciane Silva de Oliveira, Ana Júlia Felipe Camelo Aguiar, Ana Francisca Teixeira Gomes, Thaís Souza Passos, Pedro Paulo de Andrade Santos, Rafael Oliveira de Araújo Costa, Ana Heloneida de Araújo Morais, Jaluza Luana Carvalho de Queiroz, Christina da Silva Camillo, Lídia Leonize Rodrigues Matias

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 9968, p 9968 (2021)

Several studies have sought new therapies for obesity and liver diseases. This study investigated the effect of the trypsin inhibitor isolated from tamarind seeds (TTI), nanoencapsulated in chitosan and whey protein isolate (ECW), on the liver health

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add5430d7c1fec42ba85e14b82b249b7

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Biochemical characterisation of a Kunitz-type inhibitor from Tamarindus indica L. seeds and its efficacy in reducing plasma leptin in an experimental model of obesity

Autor: Daniel Nogoceke Sifuentes, Adriana F. Uchoa, Beatriz Blenda Pinheiro de Souza, Ana Heloneida de Araújo Morais, Bruna Leal Lima Maciel, Amanda Fernandes de Medeiros, Izael de Sousa Costa, Raphael Paschoal Serquiz, Elizeu Antunes dos Santos, Fabiana Maria Coimbra de Carvalho, Sumika Kiyota

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 334-348 (2018)
Journal of Enzyme Inhibition and Medicinal Chemistry
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA-Alice)
Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf7ba58c8820dadd6180be242986a49
https://doaj.org/article/bf10a091414d47a9a9f8b24c94232dd2

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Mechanism of the action of bioactive proteins of vegetables in diabetes mellitus type 2: Systematic review protocol

Autor: Ana Heloneida de Araújo Morais, Gidyenne Christine Bandeira Silva de Medeiros, Bruna Leal Lima Maciel, Izael de Sousa Costa, Amanda Fernandes de Medeiros, Grasiela Piuvezam

Publikováno v: Medicine

Background: Diabetes mellitus type 2 (DM2) is a chronic disease of significant prevalence causing hyperglycemia and several comorbidities. Evidences highlight the performance of non - protein bioactive compounds found in vegetables in the control of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b2c75cd40002818f7ecab329ca1264
https://pubmed.ncbi.nlm.nih.gov/31574867

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Anti-TNF-α Agent Tamarind Kunitz Trypsin Inhibitor Improves Lipid Profile of Wistar Rats Presenting Dyslipidemia and Diet-induced Obesity Regardless of PPAR-γ Induction

Autor: Izael de Sousa Costa, Vivian Nogueira Silbiger, Alexandre C. Serquiz, Ana Heloneida de Araújo Morais, Vanessa Cristina Oliveira de Lima, Anna Beatriz Santana Luz, Fernando Vagner Lobo Ladd, Raul Hernandes Bortolin, Elizeu Antunes dos Santos, Bruna Leal Lima Maciel, Fabiana Maria Coimbra de Carvalho

Publikováno v: Nutrients, Vol 11, Iss 3, p 512 (2019)
Nutrients
Volume 11
Issue 3

The increasing prevalence of obesity and, consequently, chronic inflammation and its complications has increased the search for new treatment methods. The effect of the purified tamarind seed trypsin inhibitor (TTIp) on metabolic alterations in Wista

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f4d6c780b97aec0f29e1dbb30eb63d
https://www.mdpi.com/2072-6643/11/3/512

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Proteínas bioativas das sementes de tamarindo reduzem leptina plasmática independente da perda de peso em ratos com obesidade

Autor: Ana Heloneida de Araújo Morais, Izael de Sousa Costa, Fabiana Maria Coimbra de Carvalho

Publikováno v: Saúde (Santa Maria). 44

Introdução: A obesidade caracteriza-se pelo acúmulo excessivo de gordura corporal, sendo essa responsável por elevadas concentrações de leptina. Pesquisas têm procurado adjuvantes no seu tratamento e as proteínas isoladas das sementes de tama

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97ae8bf627aea2ca8929491f79637fc1
https://doi.org/10.5902/2236583433094

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A Trypsin Inhibitor from Tamarind Reduces Food Intake and Improves Inflammatory Status in Rats with Metabolic Syndrome Regardless of Weight Loss

Autor: Fabiana Maria Coimbra de Carvalho, Raphael Paschoal Serquiz, Adriana F. Uchoa, Izael de Sousa Costa, Elizeu Antunes dos Santos, Maíra C. J. S. Lima, Amanda Fernandes de Medeiros, Bruna Leal Lima Maciel, Ana Heloneida de Araújo Morais, Vanessa Cristina Oliveira de Lima, Alexandre C. Serquiz

Publikováno v: Nutrients, Vol 8, Iss 10, p 544 (2016)
Nutrients; Volume 8; Issue 10; Pages: 544
Nutrients

Trypsin inhibitors are studied in a variety of models for their anti-obesity and anti-inflammatory bioactive properties. Our group has previously demonstrated the satietogenic effect of tamarind seed trypsin inhibitors (TTI) in eutrophic mouse models

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379c3f260d162da903900ddee0c5ab2f
http://www.mdpi.com/2072-6643/8/10/544

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