Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Izabella Perkins"'
Publikováno v:
DNA and Cell Biology. 27:637-648
Bacillus anthracis produces lethal toxin (LT) and edema toxin (ET), and they suppress the function of LPS-stimulated dendritic cells (DCs). Because DCs respond differently to various microbial stimuli, we compared toxin effects in bone marrow DCs sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d71b9a2f7f66feddeccc2b6379b2755
https://doi.org/10.1089/dna.2008.0760
https://doi.org/10.1089/dna.2008.0760
Publikováno v:
Infection and Immunity. 75:146-151
The progression of Legionella pneumophila infection in macrophages is controlled by the Lgn1 gene locus, which expresses the nonpermissive phenotype in cells from BALB/c mice but the permissive phenotype in cells from A/J mice. Activation of dendriti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa8f7e5cf9de20a3aea1fd6ac2fb25f
https://doi.org/10.1128/iai.01011-06
https://doi.org/10.1128/iai.01011-06
Autor:
Alberto van Olphen, Nicholas M. Burdash, Izabella Perkins, Herman Friedman, Thomas W. Klein, James Rogers
Publikováno v:
Experimental Biology and Medicine. 230:645-651
The primary polyphenol in green tea extract is the catechin epigallocatechin gallate (EGCG). Various studies have shown significant suppressive effects of catechin on mammalian cells, either tumor or normal cells, including lymphoid cells. Previous s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65760185ec0889f0d6b1a2390db7b82
https://doi.org/10.1177/153537020523000906
https://doi.org/10.1177/153537020523000906
Autor:
Herman Friedman, Izabella Perkins, Catherine Newton, Tangying Lu, Stanley J. Nazian, Thomas W. Klein
Publikováno v:
Journal of Leukocyte Biology. 76:854-861
T helper cell type 1 (Th1)-polarizing cytokines are induced by Legionella pneumophila infection and are suppressed by pretreatment with marijuana cannabinoids (CB). Glucocorticoids and prostaglandin E2(PGE2) are also reported to suppress Th1 polariza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55af09a540ac47975ffc447ddb7af0c
https://doi.org/10.1189/jlb.0304184
https://doi.org/10.1189/jlb.0304184
Autor:
Cathy Newton, Thomas W. Klein, Liang Nong, Herman Friedman, Kellie Larsen, Lily Lu, Izabella Perkins
Publikováno v:
Journal of Leukocyte Biology. 74:486-496
Studies on the effects of marijuana smoking have evolved into the discovery and description of the endocannabinoid system. To date, this system is composed of two receptors, CB1 and CB2, and endogenous ligands including anandamide, 2-arachidonoyl gly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0fdb8e4b1bb2d5f54b7980dfcc9e0d
https://doi.org/10.1189/jlb.0303101
https://doi.org/10.1189/jlb.0303101
Autor:
Nicholas M. Burdash, Alberto van Olphen, Izabella Perkins, Herman Friedman, Thomas W. Klein, James Rogers
In this chapter, primary murine (BALB/c) bone marrow-derived dendritic cells (DCs), a phagocytic monocytic cell essential for innate immunity to intracellular microorganisms like Legionella, were infected in vitro with the bacteria. In related studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59a8b455c31e1786b154c9cc890af126
https://doi.org/10.1128/9781555815660.ch78
https://doi.org/10.1128/9781555815660.ch78
Autor:
Mohamed N. Seleem, Debra Sweger, Amy M. McCord, Izabella Perkins, Scott Pangonis, Devin Gillaspie, Nammalwar Sriranganathan, Burt E. Anderson, Kellie Larsen
Publikováno v:
Applied and Environmental Microbiology. 75:5434-5436
Six broad-host-range plasmid vectors were developed to study gene expression in Bartonella henselae . The vectors were used to express a β-galactosidase reporter gene in B. henselae and to generate antisense RNA for gene knockdown. When applied to o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbc85f3dc70991b20a27a474a91929ef
https://doi.org/10.1128/aem.00949-09
https://doi.org/10.1128/aem.00949-09
Publikováno v:
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 4(1)
Legionella pneumophila infection of mice induces proinflammatory cytokines and Th1 immunity as well as rapid increases in serum levels of IL-12 and IFNgamma and splenic IL-12Rbeta2 expression. Delta-9-tetrahydrocannabinol (THC) treatment prior to inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::608b0db60d65ee0652160ca4165c81d9
https://pubmed.ncbi.nlm.nih.gov/18792785
https://pubmed.ncbi.nlm.nih.gov/18792785
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 319(1)
Marijuana cannabinoids, such as delta-9-tetrahydrocannabinoid (THC), suppress type 1 T-helper 1 (Th1) immunity in a variety of models, including infection with the intracellular pathogen Legionella pneumophila (Lp). To examine the cellular mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e238ca427177eb35cf1c75b8a7309f6a
https://pubmed.ncbi.nlm.nih.gov/16837556
https://pubmed.ncbi.nlm.nih.gov/16837556
Publikováno v:
European journal of pharmacology. 532(1-2)
Delta-9-tetrahydrocannabinol (THC) injection suppresses serum interleukin-12 (IL-12) levels in Legionella pneumophila -infected mice. Dendritic cells are a major producer of IL-12 and mouse, bone marrow-derived dendritic cell cultures produced high l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02d07f8ac13b6d19193026b7c1e068d
https://pubmed.ncbi.nlm.nih.gov/16443217
https://pubmed.ncbi.nlm.nih.gov/16443217