Zobrazeno 1 - 10 of 39 pro vyhledávání: '"Izabella M Malkiewicz"'
1
Drug-induced severe adverse reaction enhanced by human herpes virus-6 reactivation
Autor: Izabella M. Malkiewicz, Kristi K. McKinney, Lawrence Cohen, Radu M. Nanau, Vincent Kong, Tony Mazulli, Manuela G. Neuman, George Moussa
Publikováno v: Translational Research. 161:430-440
Reactivation of certain latent viruses has been linked with a more severe course of drug-induced hypersensitivity reaction (HSR). For example, reactivation of human herpes virus (HHV)-6 is associated with severe organ involvement and a prolonged cour
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2586e9c6c661b2fdf1068b6ebd0b49c
https://doi.org/10.1016/j.trsl.2012.12.012
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2
Predicting possible zonisamide hypersensitivity syndrome
Autor: Neil H. Shear, Mona Kessas, Amy W. Lee, Izabella M. Malkiewicz, Manuela G. Neuman, Lawrence Cohen
Publikováno v: Experimental Dermatology. 17:1045-1051
Zonisamide (ZNS) is an anticonvulsant (AC) that contains a sulpha moiety potentially triggering hypersensitivity syndrome reactions (HSR). The lymphocyte toxicity assay (LTA) is an in vitro drug rechallenge test, which is believed to reflect a decrea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d949a23eea300ec3bae3e2c4200d6393
https://doi.org/10.1111/j.1600-0625.2008.00748.x
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3
Immunopathogenesis of hypersensitivity syndrome reactions to sulfonamides
Autor: Masud Taeri, Neil H. Shear, Lawrence Cohen, Izabella M. Malkiewicz, Julia Haber, Manuela G. Neuman, Lori E. Shapiro, Joel S. Fish, Robert Cartotto, Manuel Gomez, Norberto Krivoy
Publikováno v: Translational Research. 149:243-253
Cytokines play a role in the immunopathological and molecular mechanisms of sulfonamide-induced hypersensitivity reactions (HSRs). The objective of this study was to analyze the reliability and correlation between the clinical symptoms observed in af
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da7af3ce57983ba5237e13a5eaa2e33
https://doi.org/10.1016/j.trsl.2006.12.001
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5
Kinetics of serum cytokines reflect changes in the severity of chronic hepatitis C presenting minimal fibrosis
Autor: Marc Bourlière, Dominique Valla, Michelle Martinot-Peignoux, Gady G Katz, Tarik Asselah, Neil H. Shear, Manuela G. Neuman, Jean-Pierre Benhamou, Izabella M. Malkiewicz, Patrick Marcellin, Asma Ibrahim
Publikováno v: Journal of Viral Hepatitis. 9:134-140
Our aims were to measure the kinetics of serum tumour necrosis alpha (TNF-alpha) and transforming growth factor beta (TGF-beta) levels as markers of progression of disease in nontreated chronic hepatitis C virus (HCV)-infected patients with minimal o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e5bd7cd429992c960abe577cb19553
https://doi.org/10.1046/j.1365-2893.2002.00343.x
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6
Tumor necrosis factor-α and transforming growth factor-β reflect severity of liver damage in primary biliary cirrhosis
Autor: Keith D. Lindor, Paul Angulo, Gady G Katz, Julia Haber, Izabella M. Malkiewicz, Roberta A. Jorgensen, Neil H. Shear, E. Rolland Dickson, Manuela G. Neuman
Publikováno v: Journal of Gastroenterology and Hepatology. 17:196-202
BACKGROUND AND AIMS The pathogenesis of primary biliary cirrhosis (PBC) is unknown. The role of cytokines such as tumor necrosis factor-alpha (TNF-alpha) and transforming growth factor-beta (TGF-beta), and the effect of ursodeoxycholic acid (UDCA) in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f0b8de37c04971e4d24156ed2eb211
https://doi.org/10.1046/j.1440-1746.2002.02672.x
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8
CYP2E1-mediated modulation of valproic acid-induced hepatocytotoxicity
Autor: Manuela G Neuman, Gady G Katz, Pearl Jacobson-Brown, Izabella M. Malkiewicz, Heather K Neilson, Neil H. Shear, Ross G. Cameron, Frank S. Abbott
Publikováno v: Clinical Biochemistry. 34:211-218
Objectives: To determine the cytotoxicity of valproic acid (VPA) and its metabolite, 4-ene-valproic acid (4-ene-VPA) in human hepatoblastoma cells (Hep G2), and to study the modulatory effect of cytochrome P450 2E1 induction in this model. Methods: C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23685be02697d07b9d4563696c27e5a6
https://doi.org/10.1016/s0009-9120(01)00217-x
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9
Cytokine network in nonresponding chronic hepatitis C patients with genotype 1: role of triple therapy with interferon alpha, ribavirin, and ursodeoxycholate
Autor: Danny Sapir, Zamir Halpern, Gady G Katz, Neil H. Shear, Asma Ibrahim, Manuela G. Neuman, Shlomo Brill, Izabella M. Malkiewicz, Sophie Magazinik, Hava Peretz, Laurence M. Blendis, Fred M. Konikoff
Publikováno v: Clinical Biochemistry. 34:183-188
Objective: (i) to characterize the profile of tumor necrosis factor alpha (TNF α), interleukin-6 (IL-6), IL 10, Fas-ligand and transforming growth factor beta (TGF β), chronic hepatitis C (HCV) patients with genotype 1; (ii) to determine the influe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8335d4018a329205dece2de9ace1775a
https://doi.org/10.1016/s0009-9120(01)00213-2
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10
Signaling for ethanol-induced apoptosis and repair in vitro
Autor: Karen Valentino, Gady G. Katz, Neil H. Shear, Izabella M. Malkiewicz, Manuela G. Neuman
Publikováno v: Clinical Biochemistry. 34:219-227
Objectives: To evaluate whether caspases are involved in ethanol (EtOH)-induced apoptosis and if polyenylphosphatidylcholine (PPC) affects apoptosis, in vitro in Hep G2 cells. Methods: Cells were treated with 100 mmol/L EtOH for 24 h and with 2 doses
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3efd41a645520753f6f938bc8d7921b
https://doi.org/10.1016/s0009-9120(01)00218-1
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