Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Izabella Damm"'
Autor:
Tara K. Sigdel, Paul A. Fields, Juliane Liberto, Izabella Damm, Maggie Kerwin, Jill Hood, Parhom Towfighi, Marina Sirota, Harlan S. Robins, Minnie M. Sarwal
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In this cross-sectional and longitudinal analysis of mapping the T-cell repertoire in kidney transplant recipients, we have investigated and validated T-cell clonality, immune repertoire chronology at rejection, and contemporaneous allograft biopsy q
Externí odkaz:
https://doaj.org/article/1b36f4a0a7014a5599e2a6c906ed8a76
Autor:
Richard Ahn, Joanna Schaenman, Zachary Qian, Harry Pickering, Victoria Groysberg, Maura Rossetti, Megan Llamas, Alexander Hoffmann, David Gjertson, Mario Deng, Suphamai Bunnapradist, Elaine F. Reed, CMV Systems Immunobiology Group, Janice Arakawa-Hoyt, Patrick Boada, Jenny Brook, Jim Cimino, Izabella Damm, Nakul Datta, Don J. Diamond, Tin Doung, Janette Gadzhyan, David Elashoff, Kenichi Ishiyama, Maggie Kerwin, Lewis L. Lanier, Erik Lum, Dane Munar, Tariq Mukatash, Michelle Ramirez, Priyanka Rashmi, Rodney Rodgers, Dimitri Rychov, Minnie M. Sarwal, Subha Sen, Tara Sigdel, Danielle Sim, Marina Sirota, Swastika Sur, Otto Yang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cytomegalovirus (CMV) viremia continues to cause significant morbidity and mortality in kidney transplant patients with clinical complications including organ rejection and death. Whole blood gene expression dynamics in CMV viremic patients from onse
Externí odkaz:
https://doaj.org/article/66617ef659554f75b140839bea412757
Autor:
Arya Zarinsefat, Jose M. Arreola Guerra, Tara Sigdel, Izabella Damm, Reuben Sarwal, Chitranon Chan-on, Gyula Szabo, Jorge L. Aguilar-Frasco, Xicohtencatl Ixtlapale-Carmona, Carlos Salinas-Ramos, Leonardo Ramirez-Martinez, Claudio Ramirez, Mario Vilatoba, Luis E. Morales Buenrostro, Josefina M. Alberu, Minnie M. Sarwal
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Long-term kidney transplant (KT) allograft outcomes have not improved as expected despite a better understanding of rejection and improved immunosuppression. Previous work had validated a computed rejection score, the tissue common rejection module (
Externí odkaz:
https://doaj.org/article/1cff4aafe0bc41de935c00a172a72d17
Autor:
Tara K. Sigdel, Paul D. Piehowski, Sudeshna Roy, Juliane Liberto, Joshua R. Hansen, Adam C. Swensen, Rui Zhao, Ying Zhu, Priyanka Rashmi, Andrew Schroeder, Izabella Damm, Swastika Sur, Jinghui Luo, Yingbao Yang, Wei-Jun Qian, Minnie M. Sarwal
Publikováno v:
Frontiers in Medicine, Vol 7 (2021)
Externí odkaz:
https://doaj.org/article/88ed030302294d25b4e0f7673a3ddff6
Autor:
Tara K. Sigdel, Paul D. Piehowski, Sudeshna Roy, Juliane Liberto, Joshua R. Hansen, Adam C. Swensen, Rui Zhao, Ying Zhu, Priyanka Rashmi, Andrew Schroeder, Izabella Damm, Swastika Sur, Jinghui Luo, Yingbao Yang, Wei-Jun Qian, Minnie M. Sarwal, The Kidney Precision Medicine Project (KPMP) Consortium
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Molecular assessments at the single cell level can accelerate biological research by providing detailed assessments of cellular organization and tissue heterogeneity in both disease and health. The human kidney has complex multi-cellular states with
Externí odkaz:
https://doaj.org/article/3732ec0f49974b1fabd73c81171d8162
Autor:
Tara K Sigdel, Joshua Y C Yang, Oriol Bestard, Andrew Schroeder, Szu-Chuan Hsieh, Juliane M Liberto, Izabella Damm, Anna C M Geraedts, Minnie M Sarwal
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220052 (2019)
A Common Rejection Module (CRM) consisting of 11 genes expressed in allograft biopsies was previously reported to serve as a biomarker for acute rejection (AR), correlate with the extent of graft injury, and predict future allograft damage. We invest
Externí odkaz:
https://doaj.org/article/8c215c1f023a43c2acb313613b4caa72
Autor:
Annelore Sacreas, Joshua Y C Yang, Bart M Vanaudenaerde, Tara K Sigdel, Juliane M Liberto, Izabella Damm, Geert M Verleden, Robin Vos, Stijn E Verleden, Minnie M Sarwal
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205107 (2018)
RATIONALE:Recent studies suggest that similar injury mechanisms are in place across different solid organ transplants, resulting in the identification of a common rejection module (CRM), consisting of 11 genes that are overexpressed during acute and,
Externí odkaz:
https://doaj.org/article/9b70b6d308e145e5bf64af41a026c54b
Autor:
Tara K Sigdel, Oriol Bestard, Tim Q Tran, Szu-Chuan Hsieh, Silke Roedder, Izabella Damm, Flavio Vincenti, Minnie M Sarwal
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138133 (2015)
Whole genome microarray meta-analyses of 1030 kidney, heart, lung and liver allograft biopsies identified a common immune response module (CRM) of 11 genes that define acute rejection (AR) across different engrafted tissues. We evaluated if the CRM g
Externí odkaz:
https://doaj.org/article/538a510e0fca4fc1b22d04af18ecd2f9
Autor:
Priyanka Rashmi, Patrick Boada, Arvind Soni, Tara K Sigdel, Dmitry Rychkov, Eunsil Hahm, Andrea Alice Da Silva, Izabella Damm, Rohan Paul, Flavio Vincenti, Jimmie Ye, Jochen Reiser, Jeffrey wolf, Minnie M. Sarwal
Circulating factors resulting from immune dysfunction have been proposed as one of the causes for increased risk of graft loss associated with recurrence of focal segmental glomerulosclerosis (FSGS) after kidney transplant. However, the precise ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e06ad7689a4ab71d833f2aa84e27f046
https://doi.org/10.1101/2023.03.06.23286859
https://doi.org/10.1101/2023.03.06.23286859
Autor:
Priyanka Rashmi, Swastika Sur, Tara K. Sigdel, Patrick Boada, Andrew W. Schroeder, Izabella Damm, Matthias Kretzler, Jeff Hodgin, George Hartoularos, Chun Jimmie Ye, Minnie M. Sarwal
Publikováno v:
Am J Transplant
Maintenance of systemic homeostasis by kidney requires the coordinated response of diverse cell types. The use of single-cell RNA sequencing (scRNAseq) for patient tissue samples remains fraught with difficulties with cell isolation, purity, and expe