Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Izabela Małuch"'
Publikováno v:
Chemosensors, Vol 9, Iss 8, p 199 (2021)
Efficient deposition of biomolecules on the surface, maintaining their full activity and stability, is a most significant factor in biosensor construction. For this reason, more and more research is focused on the development of electrochemical biose
Externí odkaz:
https://doaj.org/article/94a9e9af70d440018558e5a4e38502bc
Autor:
Izabela Małuch, Oktawian Stachurski, Paulina Kosikowska-Adamus, Marta Makowska, Marta Bauer, Dariusz Wyrzykowski, Aleksandra Hać, Wojciech Kamysz, Milena Deptuła, Michał Pikuła, Emilia Sikorska
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 23, p 8944 (2020)
Antimicrobial peptides (AMPs) constitute a promising tool in the development of novel therapeutic agents useful in a wide range of bacterial and fungal infections. Among the modifications improving pharmacokinetic and pharmacodynamic characteristics
Externí odkaz:
https://doaj.org/article/2cd53b98d72744ef8b5398c4d63b9fc0
Publikováno v:
Biochemical Journal. 478:2233-2245
Caspases are a family of enzymes that play roles in cell death and inflammation. It has been suggested that in the execution phase of the apoptotic pathway, caspase-3, -6 and -7 are involved. The substrate specificities of two proteases (caspases 3 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f564e7114f0d4a171ea8851a9d6cdf44
https://doi.org/10.1042/bcj20210255
https://doi.org/10.1042/bcj20210255
Publikováno v:
Journal of Medicinal Chemistry
The article describes the application of the alanine-scanning technique used in combination with Raman, surface-enhanced Raman, attenuated total reflection Fourier transform infrared, and surface-enhanced infrared absorption (SEIRA) spectroscopies, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce4120f36ab44e30d5aba9c907b199d
https://doi.org/10.1021/acs.jmedchem.1c00397
https://doi.org/10.1021/acs.jmedchem.1c00397
Publikováno v:
Chemistry – An Asian Journal. 14:4103-4113
Since proteases are involved in a wide range of physiological and disease states, the development of novel tools for imaging proteolytic enzyme activity is attracting increasing interest from scientists. Peptide substrates containing proteinogenic am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac22a7cb87d6ec5769aa783e2f9cfa9
https://doi.org/10.1002/asia.201901152
https://doi.org/10.1002/asia.201901152
Autor:
Franciszek Kasprzykowski, Ewa Mulkiewicz, Dariusz Wyrzykowski, Sylwia Rodziewicz-Motowidło, Maria Dzierżyńska, Aneta Pogorzelska, Emilia Sikorska, Justyna Sawicka, Izabela Małuch, Anders Grubb
Publikováno v:
Protein & Peptide Letters. 26:423-434
Background: Antibacterial peptidyl derivative - Cystapep 1, was previously found to be active both against antibiotic-resistant staphylococci and streptococci as well as antibioticsusceptible strains of these species. Therefore, it is a promising lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3cbd53057543fb8487629f500dc2cad
https://doi.org/10.2174/0929866526666190311162716
https://doi.org/10.2174/0929866526666190311162716
Publikováno v:
Chemosensors
Volume 9
Issue 8
Chemosensors, Vol 9, Iss 199, p 199 (2021)
Volume 9
Issue 8
Chemosensors, Vol 9, Iss 199, p 199 (2021)
Efficient deposition of biomolecules on the surface, maintaining their full activity and stability, is a most significant factor in biosensor construction. For this reason, more and more research is focused on the development of electrochemical biose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3299d83f9e704f8b0d40649a716b42cf
https://doi.org/10.3390/chemosensors9080199
https://doi.org/10.3390/chemosensors9080199
Autor:
Kévin Ly, Anna Kwiatkowska, Christine Levesque, Robert Day, Adam Prahl, Roxane Desjardins, Witold Neugebauer, Frédéric Couture, Izabela Małuch
Publikováno v:
Journal of Medicinal Chemistry. 60:2732-2744
The proprotein convertase family of enzymes includes seven endoproteases with significant redundancy in their cleavage activity. We previously described the peptide Ac-LLLLRVK-Amba that displays potent inhibitory effects on both PACE4 and prostate ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0284a456fb1ec33bae29b9983a41a6bd
https://doi.org/10.1021/acs.jmedchem.6b01499
https://doi.org/10.1021/acs.jmedchem.6b01499
Publikováno v:
Postępy Biochemii.
Jednym z wyzwań, przed którym stoi współczesna nauka jest przezwyciężenie wzrastającej odporności drobnoustrojów na dostępne antybiotyki. Stale rosnąca potrzeba poszukiwania nowych preparatów leczniczych o mechanizmach działania innych n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::846d757f00c1e42e6a327f1eb6b59915
https://doi.org/10.18388/pb.2019_280
https://doi.org/10.18388/pb.2019_280
Publikováno v:
Postepy biochemii. 65(4)
Antibiotics have revolutionized the pharmacology market but their "golden area" passed away. The urgent need to develop new medicins with the mechanism of action different than those already used is constantly growing because of the drug-resistance o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9e002a17032776e32bc6e5f9c73bdba
https://pubmed.ncbi.nlm.nih.gov/31945282
https://pubmed.ncbi.nlm.nih.gov/31945282