Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Izabela M D, Bastos"'
Autor:
Sébastien Charneau, Lucas Silva de Oliveira, Zenon Zenonos, Christine S. Hopp, Izabela M. D. Bastos, Damarys Loew, Bérangère Lombard, Ariane Pandolfo Silveira, Giovanna de Carvalho Nardeli Basílio Lobo, Sônia Nair Bao, Philippe Grellier, Julian C. Rayner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract The interaction of Plasmodium falciparum—infected red blood cells (iRBCs) with the vascular endothelium plays a crucial role in malaria pathology and disease. KAHRP is an exported P. falciparum protein involved in iRBC remodelling, which i
Externí odkaz:
https://doaj.org/article/e58c8b37f30448b59b50543e2190c92d
Autor:
Laís Garreto, Sébastien Charneau, Samuel Coelho Mandacaru, Otávio T. Nóbrega, Flávia N. Motta, Carla N. de Araújo, Audrey C. Tonet, Flávia M. B. Modesto, Lilian M. Paula, Marcelo Valle de Sousa, Jaime M. Santana, Ana Carolina Acevedo, Izabela M. D. Bastos
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Sjögren’s Syndrome (SS) is an autoimmune exocrinopathy characterized by the progressive damage of salivary and lacrimal glands associated with lymphocytic infiltration. Identifying new non-invasive biomarkers for SS diagnosis remains a challenge,
Externí odkaz:
https://doaj.org/article/7bd5da0eacbe4d5e8bf2fa2e32e1a180
Autor:
Natalia Gil-Jaramillo, Amanda Pereira Rocha, Tainá Raiol, Flávia Nader Motta, Cecília Favali, Marcelo M. Brigido, Izabela M. D. Bastos, Jaime M. Santana
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Chagas disease is a debilitating and neglected disease caused by the protozoan Trypanosoma cruzi. Soon after infection, interactions among T. cruzi and host innate immunity cells can drive/contribute to disease outcome. Dendritic cells (DCs), present
Externí odkaz:
https://doaj.org/article/3e0c66d40aaa4b5fbbcf0d20b615b3ab
Autor:
Camila Lasse, Clênia S. Azevedo, Carla N. de Araújo, Flávia N. Motta, Milene A. Andrade, Amanda Pereira Rocha, Iracyara Sampaio, Sébastien Charneau, Marc Gèze, Philippe Grellier, Jaime M. Santana, Izabela M. D. Bastos
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Leishmania infantum is a flagellated protozoan and one of the main causative agents of visceral leishmaniasis. This disease usually affects the human reticuloendothelial system, can cause death and available therapies may lead to serious side effects
Externí odkaz:
https://doaj.org/article/28fe34ab24e9465e909bdf351b3bb178
Autor:
Samuel C Mandacaru, Rayner M L Queiroz, Marcos R Alborghetti, Lucas S de Oliveira, Consuelo M R de Lima, Izabela M D Bastos, Jaime M Santana, Peter Roepstorff, Carlos André O Ricart, Sébastien Charneau
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225386 (2019)
Chagas disease is caused by the protozoan Trypanosoma cruzi, affecting around 8 million people worldwide. After host cell invasion, the infective trypomastigote form remains 2-4 hours inside acidic phagolysosomes to differentiate into replicative ama
Externí odkaz:
https://doaj.org/article/09b884bcf863478eb61b483f92ac5d10
Autor:
Michelle da Silva Libério, Izabela M D Bastos, Osmindo R Pires Júnior, Wagner Fontes, Jaime M Santana, Mariana S Castro
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e96893 (2014)
Peptidases are ubiquitous enzymes involved in diverse biological processes. Fragments from bioactive peptides have been found in skin secretions from frogs, and their presence suggests processing by peptidases. Thus, the aim of this work was to chara
Externí odkaz:
https://doaj.org/article/6287ce1881f64e64a36b7219e4aae4cb
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72402 (2013)
Dengue fever is caused by four distinct serotypes of the dengue virus (DENV1-4), and is estimated to affect over 500 million people every year. Presently, there are no vaccines or antiviral treatments for this disease. Among the possible targets to f
Externí odkaz:
https://doaj.org/article/0e624399758c4cedab4194069afe7485
Autor:
Flávia Nader Motta, Izabela M D Bastos, Eric Faudry, Christine Ebel, Meire M Lima, David Neves, Michel Ragno, João Alexandre R G Barbosa, Sônia Maria de Freitas, Jaime Martins Santana
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30431 (2012)
Oligopeptidase B, a processing enzyme of the prolyl oligopeptidase family, is considered as an important virulence factor in trypanosomiasis. Trypanosoma cruzi oligopeptidase B (OPBTc) is involved in host cell invasion by generating a Ca(2+)-agonist
Externí odkaz:
https://doaj.org/article/ed9dd3d01aa64e6e944417b108c3dfed
Autor:
Alexandra Galetović, Renata T Souza, Marcia R M Santos, Esteban M Cordero, Izabela M D Bastos, Jaime M Santana, Jeronimo C Ruiz, Fabio M Lima, Marjorie M Marini, Renato A Mortara, José Franco da Silveira
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27634 (2011)
BACKGROUND: Trypanosoma cruzi has a single flagellum attached to the cell body by a network of specialized cytoskeletal and membranous connections called the flagellum attachment zone. Previously, we isolated a DNA fragment (clone H49) which encodes
Externí odkaz:
https://doaj.org/article/531fcc1d2e374685925b71e5252e916f
Autor:
Rayner M L, Queiroz, Carlos A O, Ricart, Mara O, Machado, Izabela M D, Bastos, Jaime M, de Santana, Marcelo V, de Sousa, Peter, Roepstorff, Sébastien, Charneau
Publikováno v:
Frontiers in Chemistry
The protozoan parasite Trypanosoma cruzi causes Chagas disease, one of the major neglected infectious diseases. It has the potential to infect any nucleated mammalian cell. The secreted/excreted protein repertoire released by T. cruzi trypomastigotes