Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Izabela Glegola-Madejska"'
Autor:
Vishwas Mishra, Anna Crespo-Puig, Callum McCarthy, Tereza Masonou, Izabela Glegola-Madejska, Alice Dejoux, Gabriella Dow, Matthew J. G. Eldridge, Luciano H. Marinelli, Meihan Meng, Shijie Wang, Daniel J. Bennison, Rebecca Morrison, Avinash R. Shenoy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The cytokine interleukin-1β (IL-1β) has pivotal roles in antimicrobial immunity, but also incites inflammatory disease. Bioactive IL-1β is released following proteolytic maturation of the pro-IL-1β precursor by caspase-1. UBE2L3, a ubiqu
Externí odkaz:
https://doaj.org/article/660af0374b2c4cafadff2b7f923d181b
Autor:
Komal Umashankar Rao, Domhnall Iain Henderson, Nitya Krishnan, Manoj Puthia, Izabela Glegola-Madejska, Lena Brive, Fanny Bjarnemark, Anna Millqvist Fureby, Karin Hjort, Dan I. Andersson, Erik Tenland, Erik Sturegård, Brian D. Robertson, Gabriela Godaly
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Alternative ways to prevent and treat infectious diseases are needed. Previously, we identified a fungal peptide, NZX, that was comparable to rifampicin in lowering M. tuberculosis load in a murine tuberculosis (TB) infection model. Here we
Externí odkaz:
https://doaj.org/article/8ef6d83379c541af9973c901102863f4
Autor:
Caroline Mullineaux-Sanders, Danielle Carson, Eve G. D. Hopkins, Izabela Glegola-Madejska, Alejandra Escobar-Zepeda, Hilary P. Browne, Trevor D. Lawley, Gad Frankel
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Gut bacterial infections involve three-way interactions between virulence factors, the host immune responses, and the microbiome. While the microbiome erects colonization resistance barriers, pathogens employ virulence factors to overcome them.
Externí odkaz:
https://doaj.org/article/26b6e62002a94344be6faf9d79c3a812
Autor:
Erik Tenland, Alexander Pochert, Nitya Krishnan, Komal Umashankar Rao, Sadaf Kalsum, Katharina Braun, Izabela Glegola-Madejska, Maria Lerm, Brian D Robertson, Mika Lindén, Gabriela Godaly
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212858 (2019)
BackgroundIntracellular delivery of antimicrobial agents by nanoparticles, such as mesoporous silica particles (MSPs), offers an interesting strategy to treat intracellular infections. In tuberculosis (TB), Mycobacterium tuberculosis avoids component
Externí odkaz:
https://doaj.org/article/b056ebfe1b4f4fa29a148aed1edf1baa
Autor:
Vishwas Mishra, Anna Crespo-Puig, Callum McCarthy, Tereza Masonou, Izabela Glegola-Madejska, Alice Dejoux, Gabriella Dow, Matthew J. G. Eldridge, Luciano H. Marinelli, Meihan Meng, Shijie Wang, Daniel J. Bennison, Avinash R. Shenoy
The cytokine interleukin-1β (IL-1β) has pivotal roles in antimicrobial immunity, but also incites inflammatory pathology. Bioactive IL-1β is released following proteolytic maturation of the pro-IL-1β precursor by caspase-1 inflammasomes. UBE2L3/U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b57e468eb0910dc187cf17569715ba5
https://doi.org/10.1101/2022.09.14.507790
https://doi.org/10.1101/2022.09.14.507790
Autor:
Izabela Glegola-Madejska, Gad Frankel, Caroline Mullineaux-Sanders, Alejandra Escobar-Zepeda, Trevor D. Lawley, Eve G D Hopkins, Hilary P. Browne, Danielle Carson
Publikováno v:
mBio
mBio, Vol 12, Iss 5 (2021)
mBio, Vol 12, Iss 5 (2021)
The gut microbiota plays a crucial role in susceptibility to enteric pathogens, including Citrobacter rodentium, a model extracellular mouse pathogen that colonizes the colonic mucosa. C. rodentium infection outcomes vary between mouse strains, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44d31ca709a92977a96741c3a22a547
http://hdl.handle.net/10044/1/91671
http://hdl.handle.net/10044/1/91671
Autor:
Sophie Helaine, Izabela Glegola-Madejska, Catrin Beetham, Ana Laura Moldoveanu, Robert A. Fisher, Séverin Ronneau, Molly Sargen, Peter W. S. Hill
Publikováno v:
Cell hostmicrobe. 29(12)
Summary Tolerance and persistence are superficially similar phenomena by which bacteria survive bactericidal antibiotics. It is assumed that the same physiology underlies survival of individual tolerant and persistent bacteria. However, by comparing
Autor:
Caroline Mullineaux-Sanders, Theodoros I. Roumeliotis, Massiel Cepeda-Molero, David Ruano-Gallego, Izabela Glegola-Madejska, Jyoti S. Choudhary, Naama Wagner, Alfonso Rodríguez-Patón, Tal Pupko, Zuzanna Kozik, Elena Núñez-Berrueco, Luis Ángel Fernández, Sabrina L. Slater, Gad Frankel, Julia Sanchez-Garrido, Jasmine Naemi-Baghshomali Clark
Publikováno v:
DIGITAL.INTA Repositorio Digital del Instituto Nacional de Técnica Aeroespacial
instname
instname
INTRODUCTION Infections with many Gram-negative pathogens, including Escherichia coli, Salmonella, Shigella, and Yersinia, rely on the injection of effectors via type III secretion systems (T3SSs). The effectors hijack cellular processes through mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a0310bdf1639a68da27021824eab27
https://hdl.handle.net/20.500.12666/555
https://hdl.handle.net/20.500.12666/555
Autor:
Izabela Glegola-Madejska, Komal Umashankar Rao, Sadaf Kalsum, Brian D. Robertson, Alexander Pochert, Erik Tenland, Gabriela Godaly, Katharina Braun, Nitya Krishnan, Mika Lindén, Maria Lerm
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212858 (2019)
PLoS ONE
PLoS ONE
Background Intracellular delivery of antimicrobial agents by nanoparticles, such as mesoporous silica particles (MSPs), offers an interesting strategy to treat intracellular infections. In tuberculosis (TB), Mycobacterium tuberculosis avoids componen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6abab767a9e0f8d4f1e29a8e890fda3b
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-155571
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-155571
Autor:
Benjamin H, Mullish, Julie A K, McDonald, Alexandros, Pechlivanis, Jessica R, Allegretti, Dina, Kao, Grace F, Barker, Diya, Kapila, Elaine O, Petrof, Susan A, Joyce, Cormac G M, Gahan, Izabela, Glegola-Madejska, Horace R T, Williams, Elaine, Holmes, Thomas B, Clarke, Mark R, Thursz, Julian R, Marchesi
Publikováno v:
Gut. 68(10)
Faecal microbiota transplant (FMT) effectively treats recurrentUsing stool collected from patients and donors pre-FMT/post-FMT for rCDI, we performed 16S rRNA gene sequencing, ultra performance liquid chromatography mass spectrometry (UPLC-MS) bile a