Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Izabela A. Rodenhuis-Zybert"'
Autor:
Juan Felipe Valdés-López, Lady Johana Hernández-Sarmiento, Y. S. Tamayo-Molina, Paula A. Velilla-Hernández, Izabela A. Rodenhuis-Zybert, Silvio Urcuqui-Inchima
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Interferons (IFNs) are a family of cytokines that activate the JAK-STAT signaling pathway to induce an antiviral state in cells. Interleukin 27 (IL-27) is a member of the IL-6 and/or IL-12 family that elicits both pro- and anti-inflammatory responses
Externí odkaz:
https://doaj.org/article/e734f987932d457aa3a1ee10cfd5de1c
Autor:
Vinit Upasani, Bram M. ter Ellen, Sotheary Sann, Sokchea Lay, Sothy Heng, Denis Laurent, Sowath Ly, Veasna Duong, Philippe Dussart, Jolanda M. Smit, Tineke Cantaert, Izabela A. Rodenhuis-Zybert
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e17265- (2023)
Dengue virus infection results in a broad spectrum of diseases ranging from mild dengue fever (DF) to severe dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Hitherto, there is no consensus biomarker for the prediction of severe dengue
Externí odkaz:
https://doaj.org/article/6571c78510974df5859a2edda28959b5
Autor:
José Alberto Aguilar Briseño, Lennon Ramos Pereira, Marleen van der Laan, Mindaugas Pauzuolis, Bram M Ter Ellen, Vinit Upasani, Jill Moser, Luís Carlos de Souza Ferreira, Jolanda M Smit, Izabela A Rodenhuis-Zybert
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010499 (2022)
Severe dengue virus (DENV) infection is characterized by exacerbated inflammatory responses that lead to endothelial dysfunction and plasma leakage. We have recently demonstrated that Toll-like receptor 2 (TLR2) on blood monocytes senses DENV infecti
Externí odkaz:
https://doaj.org/article/8ed23dd06b8b42bbac9a4af850b0e6eb
Autor:
Bram M. ter Ellen, Jelmer Niewold, Antine Flikweert, Anneke C. Muller Kobold, Peter Heeringa, Matijs van Meurs, Jolanda M. Smit, Peter H. J. van der Voort, Izabela A. Rodenhuis-Zybert, Jill Moser
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Clinical observations have shown that obesity is associated with the severe outcome of SARS-CoV-2 infection hallmarked by microvascular dysfunction in the lungs and other organs. Excess visceral fat and high systemic levels of adipose tissue (AT) der
Externí odkaz:
https://doaj.org/article/1a9f1015c76f42d3b6ab2997db4c4c0a
Autor:
Adriana Tami, Bernardina T. F. van der Gun, Karin I. Wold, María F. Vincenti-González, Alida C. M. Veloo, Marjolein Knoester, Valerie P. R. Harmsma, Gerolf C. de Boer, Anke L. W. Huckriede, Daniele Pantano, Lilli Gard, Izabela A. Rodenhuis-Zybert, Vinit Upasani, Jolanda Smit, Akkelies E. Dijkstra, Jacco J. de Haan, Jip M. van Elst, Jossy van den Boogaard, Shennae O’ Boyle, Luis Nacul, Hubert G. M. Niesters, Alex W. Friedrich
Publikováno v:
PLoS ONE, Vol 17, Iss 11 (2022)
Background Guidelines on COVID-19 management are developed as we learn from this pandemic. However, most research has been done on hospitalised patients and the impact of the disease on non-hospitalised and their role in transmission are not yet well
Externí odkaz:
https://doaj.org/article/539be222ea39407e89bea4f3560a60b1
Autor:
José A. Aguilar-Briseño, Vinit Upasani, Bram M. ter Ellen, Jill Moser, Mindaugas Pauzuolis, Mariana Ruiz-Silva, Sothy Heng, Denis Laurent, Rithy Choeung, Philippe Dussart, Tineke Cantaert, Jolanda M. Smit, Izabela A. Rodenhuis-Zybert
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The mechanisms underlying immunpathologies in dengue virus (DENV) infection are incompletely understood. Here, authors show that TLR2 recognizes DENV particles inducing cytokine expression and activating vascular endothelium cells in vitro, and that
Externí odkaz:
https://doaj.org/article/85dea333a8ac4394b33be3faacbbdbda
Autor:
Berit Troost-Kind, Martijn J van Hemert, Denise van de Pol, Heidi van der Ende-Metselaar, Andres Merits, Malte Borggrewe, Izabela A Rodenhuis-Zybert, Jolanda M Smit
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009916 (2021)
Tomatidine, a natural steroidal alkaloid from unripe green tomatoes has been shown to exhibit many health benefits. We recently provided in vitro evidence that tomatidine reduces the infectivity of Dengue virus (DENV) and Chikungunya virus (CHIKV), t
Externí odkaz:
https://doaj.org/article/c15790ef693b4450ab597ace566969b1
Autor:
Jorge Andrés Castillo, Diana M Giraldo, Juan C Hernandez, Jolanda M Smit, Izabela A Rodenhuis-Zybert, Silvio Urcuqui-Inchima
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009873 (2021)
A dysregulated or exacerbated inflammatory response is thought to be the key driver of the pathogenesis of severe disease caused by the mosquito-borne dengue virus (DENV). Compounds that restrict virus replication and modulate the inflammatory respon
Externí odkaz:
https://doaj.org/article/63db230099ec4adf8a56a23c23246927
Autor:
Antine W. Flikweert, Anneke C. Muller Kobold, Simone van der Sar-van der Brugge, Peter Heeringa, Izabela A. Rodenhuis-Zybert, Johan Bijzet, Adriana Tami, Bernardina T. F. van der Gun, Karin I. Wold, Anke Huckriede, Hildegard Franke, Judith M. A. Emmen, Marloes Emous, Marco J. J. H. Grootenboers, Matijs van Meurs, Peter H. J. van der Voort, Jill Moser
Publikováno v:
International Journal of Obesity, 47, 126-137. Nature Publishing Group
Background Obesity is a risk factor for adverse outcomes in COVID-19, potentially driven by chronic inflammatory state due to dysregulated secretion of adipokines and cytokines. We investigated the association between plasma adipokines and COVID-19 s
Autor:
Vinit Upasani, Hoa Thi My Vo, Heidi Auerswald, Denis Laurent, Sothy Heng, Veasna Duong, Izabela A. Rodenhuis-Zybert, Philippe Dussart, Tineke Cantaert
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Dengue is an acute viral disease caused by dengue virus (DENV), which is transmitted by Aedes mosquitoes. Symptoms of DENV infection range from inapparent to severe and can be life-threatening. DENV replicates in primary immune cells such as dendriti
Externí odkaz:
https://doaj.org/article/12cda0a063924b3e988a9ea87bf5233c