Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Izabel C.P.P. Frugulhetti"'
Autor:
Thiago Moreno L. Souza, Dumith Chequer Bou-Habib, Maria Cecília B. V. de Souza, Diego Q. Rodrigues, Vitor F. Ferreira, Izabel C.P.P. Frugulhetti, Isakelly P. Marques, Fernanda da C. Santos, Carlos Frederico Leite Fontes, Anna C. Cunha
Publikováno v:
Current HIV Research. 7:327-335
We recently described that the chloroxoquinolinic ribonucleoside 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid (compound A) inhibits the human immunodeficiency virus type 1 (HIV-1) enzyme reverse transcriptase (RT),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f15b5998523e7581d02f79527e41e225
https://doi.org/10.2174/157016209788347958
https://doi.org/10.2174/157016209788347958
Autor:
Carlos Rangel Rodrigues, Helena Carla Castro, Rafael Garrett, Percilene Fazolin Vegi, Paula Alvarez Abreu, Izabel C.P.P. Frugulhetti, Alice M. R. Bernardino, Ilídio F. Afonso, Claudio Cesar Cirne Santos, Francisco das Chagas Abreu da Silveira, Lucio Mendes Cabral, Dilvani Oliveira Santos, Luiz C. S. Pinheiro, Julio C. Borges, Alexandre Reis de Azevedo, Bruno Leal
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:8196-8204
Antibacterial resistance is a complex problem that contributes to health and economic losses worldwide. The Staphylococcus epidermidis is an important nosocomial pathogen that affects immunocompromised patients or those with indwelling devices. Curre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284dbca54e38789a4a3ca3e66911bf54
https://doi.org/10.1016/j.bmc.2008.07.035
https://doi.org/10.1016/j.bmc.2008.07.035
Autor:
Vitor F. Ferreira, Carla Veronica B. Santos Canuto, Carlos Frederico Leite Fontes, Maria Cecília B. V. de Souza, Isakelly P. Marques, Izabel C.P.P. Frugulhetti, Thiago Moreno L. Souza
Publikováno v:
Antiviral Research. 77:20-27
We describe in this paper that the synthetic chloroxoquinolinic ribonucleoside 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid (compound A) and its free aglycogene base (compound B) inhibit, with low cytotoxicity, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9beb78df853c3a8460ce12e9f33a5d
https://doi.org/10.1016/j.antiviral.2007.08.011
https://doi.org/10.1016/j.antiviral.2007.08.011
Autor:
Letícia V. Faro, Carla Veronica B. Santos Canuto, Anna C. Cunha, Gilberto A. Romeiro, Claudia R. B. Gomes, Fernanda da C. Santos, Vitor F. Ferreira, Isakelly P. Marques, Maria Cecília B. V. de Souza, Izabel C.P.P. Frugulhetti, Thiago Moreno L. Souza
Publikováno v:
Letters in Drug Design & Discovery. 4:404-409
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f678fbf57cd79e1f8daab4a7616a3f33
https://doi.org/10.2174/157018007781387818
https://doi.org/10.2174/157018007781387818
Autor:
Juliano Sabatini-Lopes, Izabel C.P.P. Frugulhetti, Alice M. R. Bernardino, Gilberto A. Romeiro, Jane Maria Carvalho, Vitor F. Ferreira, Marcos A. Vannier-Santos, Helena Carla Castro, Natália I.V. Loureiro, Luiz C. S. Pinheiro, Julio C. Borges, Carlos Rangel Rodrigues, Adriana Lanfredi-Rangel
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:5765-5770
In this work, we performed the design, synthesis, and the structure-activity relationship studies of 13 new derivatives of thieno[2,3-b]pyridine. These derivatives were prepared in high yields (96-70%) and their structures were elucidated by IR, (1)H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca357cbc68deff97847d9e74778af02
https://doi.org/10.1016/j.bmc.2006.03.013
https://doi.org/10.1016/j.bmc.2006.03.013
Autor:
Izabel C.P.P. Frugulhetti, Luciana Jesus Costa, Nissin Moussatche, Helena De Souza Pereira, Ricardo Sobhie Diaz, Diana Negrão Cavalcanti, Valéria Laneuville Teixeira, L.R. Leão-Ferreira
Publikováno v:
Antiviral Research. 64:69-76
The antiviral effect of the CH(2)Cl(2)/MeOH-soluble fraction from the alga Dictyota menstrualis on HIV-1 replication was evaluated in vitro. The antiretroviral activity was attributed to two diterpenes: (6R)-6-hydroxydichotoma-3,14-diene-1,17-dial, n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c56472396f972b99ecfad4b2d7dd07a
https://doi.org/10.1016/j.antiviral.2004.06.006
https://doi.org/10.1016/j.antiviral.2004.06.006
Autor:
Izabel C.P.P. Frugulhetti, Adriana Carvalho, Gabriele Sant'anna, Thereza Quirico-Santos, Claudio Cesar Cirne Santos, Soniza Vieira Alves Leon
Publikováno v:
Arquivos de Neuro-Psiquiatria. 61:968-973
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the human central nervous system (CNS) mediated by autoimmune Th1 lymphocytes. We determined the serum levels of autoantibodies for myelin basic protein (MBP), proteolipid (PL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4611dbfd951eb14e689aebd8b13461b3
https://doi.org/10.1590/s0004-282x2003000600015
https://doi.org/10.1590/s0004-282x2003000600015
Autor:
Izabel C.P.P. Frugulhetti, Luiz Roberto Leao Ferreira, Maria Cecília B. V. de Souza, Carla Veronica B. dos Santos, Thatyana R. Alves, Vitor F. Ferreira, Jose C. Torres, Simon J. Garden, Helena S. Pereira, Angelo C. Pinto, Mara R. P. de Oliveira, Nissin Moussatche
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 21:825-835
A series of novel substituted isatin ribonucleosides 3b–3f were synthesized in good yields by a TMSOTf catalysed coupling reaction between the silylated nitrogenated base (1b–1f) and 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose (2). Isatin nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a5e7d6d477ba457ed314f4e54acc3d
https://doi.org/10.1081/ncn-120016510
https://doi.org/10.1081/ncn-120016510
Autor:
Carla V.B. Santos, Nissan Moussatch, Maria Ceclia B. V. de Souza, Anderson D. da Matta, Helena De Souza Pereira, Vitor F. Ferreira, Mara R. P. de Oliveira, Izabel C.P.P. Frugulhetti
Publikováno v:
Heteroatom Chemistry. 10:197-202
A series of new ribonucleosides 1a–d having 4-oxoquinoline-3-carboxylic acid substituted with a chloro or bromo atom in the aromatic ring, as the nitrogen base, was synthesized and examined for anti-HIV activity. Compounds 1a and 1c showed a modest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::328dbf1c218731d0714a5eaa9b6ca556
https://doi.org/10.1002/(sici)1098-1071(1999)10:3<197::aid-hc4>3.0.co
https://doi.org/10.1002/(sici)1098-1071(1999)10:3<197::aid-hc4>3.0.co
Autor:
Izabel C.P.P. Frugulhetti, Mauro Romero Leal Passos, Silvia Maria Baeta Cavalcanti, Maria Evangelina Ferreira Fonseca, L.H.S. Oliveira
Publikováno v:
Memórias do Instituto Oswaldo Cruz., Vol 89, Iss 4, Pp 575-580 (1994)
Memórias do Instituto Oswaldo Cruz, Volume: 89, Issue: 4, Pages: 575-580, Published: DEC 1994
Europe PubMed Central
Memórias do Instituto Oswaldo Cruz, Volume: 89, Issue: 4, Pages: 575-580, Published: DEC 1994
Europe PubMed Central
A hundred-sixty paraffin-embedded specimens from female cervical lesions were examined for human papillomavirus (HPV) types 6, 11, 16 and 18 infections by non-isotopic in situ hybridization. The data were compared with histologic diagnosis. Eighty-ei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d2cd9b865ddf9f2d20078552917f3e
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761994000400013
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761994000400013