Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Izabel C P, Paixão"'
Autor:
Milene D, Miranda, Otávio Augusto, Chaves, Alice S, Rosa, Alexandre R, Azevedo, Luiz Carlos da Silva, Pinheiro, Vinicius C, Soares, Suelen S G, Dias, Juliana L, Abrantes, Alice Maria R, Bernardino, Izabel C P, Paixão, Thiago Moreno L, Souza, Carlos Frederico L, Fontes
Publikováno v:
International journal of molecular sciences. 23(15)
Herpes simplex virus type-1 (HSV-1) infection causes several disorders, and acyclovir is used as a reference compound. However, resistant strains are commonly observed. Herein, we investigate the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::387066b3ffea24f2b156a34c6dd70c76
https://pubmed.ncbi.nlm.nih.gov/35897709
https://pubmed.ncbi.nlm.nih.gov/35897709
Autor:
Izabel C. P. Paixão, José Paulo Gagliardi Leite, Pedro N. Batalha, Robson Ss Marinho, David de O. Silva, Ivson L. Gama, Luana da Sm Forezi, Ana Maria Viana Pinto, Maria C. Β. V. de Souza, Fernanda da C. S. Boechat, Anna C. Cunha, Letícia V. Faro
Publikováno v:
Antiviral Therapy. 25:13-20
Background Bovine herpesvirus type 5 is an important agent of meningoencephalitis in cattle and has been identified in outbreaks of bovine neurological disease in several Brazilian states. In recent years, oxoquinoline derivatives have become an impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c42265df42f842b5f3d79026a3c08bf
https://doi.org/10.3851/imp3329
https://doi.org/10.3851/imp3329
Autor:
Izabel C. P. Paixão, Alice M. R. Bernardino, Helena De Souza Pereira, Gustavo Polillo, Julio C. Borges, Beatriz C. L. Melo, Michele S. Ribeiro
Publikováno v:
Journal of Heterocyclic Chemistry. 54:3051-3055
This paper describes the synthesis of several new 4-arylaminoquinoline-3-carbonitriles derivatives. These were evaluated on the activity reverse transcriptase (RT) of HIV-1. Most of the synthesized compounds showed significant in vitro inhibition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b887e0fbe7c12addd6ee26a897d4eebd
https://doi.org/10.1002/jhet.2914
https://doi.org/10.1002/jhet.2914
Autor:
Lorena da Graça Pedrosa de Macena, Bernardo Freitas Paula, Mirian de Araujo Carlos Crapez, Lidia Maria Fontes Amorim, Izabel C. P. Paixão, Davis Fernandes Ferreira, Ommega Internationals, Juliana Eymara Fernandes Barbosa, Aguinaldo Nepomuceno, Juliana Eymara Barbosa, Priscila Santana Pereira, Viveca Giongo, VinÃcius Vogel
Publikováno v:
Journal of Marine Biology and Aquaculture. 2:1-10
Marine viruses are among the most common, abundant and diverse biological entities in seawater columns. Despite this, little is yet know about virus abundance and distribution in tropical aquatic ecosystems. Here, we evaluated virus abundance and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22b9a61e4739bc48d94b6647155778cf
https://doi.org/10.15436/2381-0750.16.013
https://doi.org/10.15436/2381-0750.16.013
Autor:
Gabriel Vasconcelos, Luciana Palomba, Salvatore Giovanni De Simone, Annarita Falanga, Stefania Galdiero, Maria D. Vargas, Viveca Giongo, Izabel C. P. Paixão
Publikováno v:
Anais do V Seminário Anual Científico e Tecnológico de Bio-Manguinhos.
Today almost 67% of individuals with age up to 49 years are infected with HSV-1 and 50% of them, with age between 15-49, are infected with genital HSV-1. Naphthoquinones derivatives synthetized by Mannich base derived possess an efficient ability to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4574c97bc13dc10e6ba45c58aca9b492
https://doi.org/10.35259/isi.sact.2017_25833
https://doi.org/10.35259/isi.sact.2017_25833
Autor:
Izabel C. P. Paixão, Julliane Diniz Yoneda, Viveca Giongo, Magaly Girão Albuquerque, Maria Cecília B. V. de Souza, Vitor F. Ferreira, Anna C. Cunha, Fernanda da C. Santos, Leonardo Brozeguini, Kátia Zaccur Leal, Claudio Cesar Cirne-Santos, Pedro N. Batalha, Peter Rudolf Seidl, Ricardo Bicca de Alencastro
Publikováno v:
Journal of Molecular Structure. 1074:263-270
Although there are many antiviral drugs available for the treatment of herpes simplex virus (HSV) infections, still the synthesis of new anti-HSV candidates is an important strategy to be pursued, due to the emergency of resistant HSV strains mainly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d98e489c2993ebc09fd03058a0eedd10
https://doi.org/10.1016/j.molstruc.2014.05.081
https://doi.org/10.1016/j.molstruc.2014.05.081
Autor:
Fernanda Serpa Cardoso, Ruth Mariani, Izabel C. P. Paixão, Helena Carla Castro, Cristina Maria Carvalho Delou
Publikováno v:
Creative Education. :1224-1234
Gifted and talented children are known as those with a valuable potential that may be stimulated to the benefit of humankind. However, in many countries they are known as those that don’t need any specialized educational assistance or stimulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ad30c857456e765e4f216304dfc5c29
https://doi.org/10.4236/ce.2014.513138
https://doi.org/10.4236/ce.2014.513138
Autor:
Izabel C. P. Paixão, Priscilla O. Esteves, Valeria T. Laneuvlille, Claudio Cesar Cirne-Santos, Mariana Cavalcante de Oliveira, Caroline de Souza Barros
Publikováno v:
Natural Product Communications. 14:1934578X1987829
The discovery of new substances that present innumerable biological activities for the development of drugs is increasingly difficult. Natural marine products are a source of substances with a diversified chemical structure, a broad spectrum of biolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b76eea7ed39ffbee9c5066305e75f9e1
https://doi.org/10.1177/1934578x19878295
https://doi.org/10.1177/1934578x19878295
Autor:
Izabel C. P. Paixão, Carlos Frederico Leite Fontes, Diana Negrão Cavalcanti, Jussara P. Barbosa, Valéria Laneuville Teixeira, Thiago Moreno L. Souza, Renato Crespo Pereira, Juliana L. Abrantes
Publikováno v:
Planta Medica. 76:339-344
We describe in this paper that the diterpenes 8,10,18-trihydroxy-2,6-dolabelladiene ( 1) and (6 R)-6-hydroxydichotoma-4,14-diene-1,17-dial ( 2), isolated from the marine algae DICTYOTA PFAFFII and D. MENSTRUALIS, respectively, inhibited HSV-1 infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9cb110b9c8f872c19a2af071333bf87
https://doi.org/10.1055/s-0029-1186144
https://doi.org/10.1055/s-0029-1186144
Autor:
Christiane M. Nogueira, Maria Cecília B. V. de Souza, Vitor F. Ferreira, Jairo R. Temerozo, Izabel C. P. Paixão, Claudio Cesar Cirne-Santos, Anna C. Cunha, Viveca Giongo, Carlos Rangel Rodrigues, Bruno R. Simonetti, Dumith Chequer Bou-Habib, Juliana Eymara Barbosa, Pedro N. Batalha, David de O. Silva, Thiago Moreno L. Souza, Paula Alvarez Abreu, Helena Carla Castro, Valéria Garrido, Fernanda da C. Santos
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:5476-5481
In the present article, we describe the synthesis, anti-HIV1 profile and molecular modeling evaluation of 11 oxoquinoline derivatives. The structure-activity relationship analysis revealed some stereoelectronic properties such as LUMO energy, dipole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb80a5a6053668b2309e613d748a86ab
https://doi.org/10.1016/j.bmc.2009.06.037
https://doi.org/10.1016/j.bmc.2009.06.037