Výsledky vyhledávání - "Izabel Bérard"

Temporal and spatial features of the formation of DNA adducts in sulfur mustard-exposed skin

Autor: Thierry Douki, Marine Bertoni, Izabel Bérard, Sandy Emorine, Mohamed Batal, Stéphane Mouret, Isabelle Boudry, Julien Wartelle, Cécile Cléry-Barraud

Publikováno v: Toxicology and applied pharmacology
Toxicology and applied pharmacology, 2013, 273 (3), pp.644-650
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Sulfur mustard (SM) is a chemical warfare agent that targets skin where it induces large blisters. DNA alkylation is a critical step to explain SM-induced cutaneous symptoms. We determined the kinetics of formation of main SM-DNA adducts and compare

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::073f5f45e80d7c8df75fe29435b97173
https://doi.org/10.1016/j.taap.2013.10.010

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N4-Methylation of Cytosine Drastically Favors the Formation of (6-4) Photoproducts in a TCG Context

Autor: Jarah A. Meador, Thierry Douki, Aude Wack, Izabel Bérard

Publikováno v: Photochemistry and Photobiology
Photochemistry and Photobiology, Wiley, 2015, 91 (1), pp.102-108. ⟨10.1111/php.12365⟩
Photochemistry and Photobiology, 2015, 91 (1), pp.102-108. ⟨10.1111/php.12365⟩

International audience; Methylation of cytosine is a common biological process both in prokaryotic and eukaryotic cells. In addition to 5-methylcytosine (5mC), some bacterial species contain in their genome N-4-methylcytosine (N4mC). Methylation at C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f16c029b9eb0b61ce96f39b7406a1941
https://hal.archives-ouvertes.fr/hal-01589780

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Contribution of Cytosine-Containing Cyclobutane Dimers to DNA Damage Produced by Photosensitized Triplet-Triplet Energy Transfer

Autor: Aude Wack, Sigrid Andrä, Izabel Bérard, Thierry Douki

Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2014, 20 (19), pp.5787-5794. ⟨10.1002/chem.201303905⟩
Chemistry-A European Journal, 2014, 20 (19), pp.5787-5794. ⟨10.1002/chem.201303905⟩

Mutagenic cyclobutane pyrimidine dimers (CPDs) can be induced in DNA through either direct excitation or photosensitized triplet-triplet energy transfer (TTET). In the latter pathway, thymines are expected to receive the excitation energy from the ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e9c166d943802990252c0c74f33a0f
https://hal.archives-ouvertes.fr/hal-01869646

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DNA damage in internal organs after cutaneous exposure to sulphur mustard

Autor: Stéphane Mouret, Cécile Cléry-Barraud, Mohamed Batal, Izabel Bérard, Julien Wartelle, Isabelle Boudry, Thierry Douki

Publikováno v: Toxicology and applied pharmacology. 278(1)

Sulphur mustard (SM) is a chemical warfare agent that attacks mainly skin, eye and lungs. Due to its lipophilic properties, SM is also able to diffuse through the skin and reach internal organs. DNA represents one of the most critical molecular targe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f89978dd827586612f33385808c33af
https://pubmed.ncbi.nlm.nih.gov/24732442

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