Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Iyadh Douagi"'
Autor:
Mikala JoAnn Simpson, Anna Minh Newen, Christopher McNees, Sukriti Sharma, Dylan Pfannenstiel, Thomas Moyer, David Stephany, Iyadh Douagi, Qiao Wang, Christian Thomas Mayer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Self-reactive and polyreactive B cells generated during B cell development are silenced by either apoptosis, clonal deletion, receptor editing or anergy to avoid autoimmunity. The specific contribution of apoptosis to normal B cell developme
Externí odkaz:
https://doaj.org/article/4927b00f994b4c80acfe07e8b4837ec0
Autor:
Magdalena Wagner, Masahito Yoshihara, Iyadh Douagi, Anastasios Damdimopoulos, Sarita Panula, Sophie Petropoulos, Haojiang Lu, Karin Pettersson, Kerstin Palm, Shintaro Katayama, Outi Hovatta, Juha Kere, Fredrik Lanner, Pauliina Damdimopoulou
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The outer lining or cortex of the human ovary determines fertility and has been postulated to contain oogonial stem cells. Here, the authors generate a single-cell map of the adult human ovarian cortex and show that DDX4 labels perivascular cells but
Externí odkaz:
https://doaj.org/article/e6b0eb324cf54b6ca3c0777743fe76df
Autor:
Alvaro Plaza Reyes, Sandra Petrus-Reurer, Sara Padrell Sánchez, Pankaj Kumar, Iyadh Douagi, Hammurabi Bartuma, Monica Aronsson, Sofie Westman, Emma Lardner, Helder André, Anna Falk, Emeline F. Nandrot, Anders Kvanta, Fredrik Lanner
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Whilst pigmentation has been used to identify retinal pigment epithelial (RPE) cells, surface markers for these cells remain unclear. Here, the authors define surface markers for the RPE including CD140b, which help produce hPSC-derived RPE cells at
Externí odkaz:
https://doaj.org/article/a87b6c42eab14b69bd24544416acca50
Autor:
Alvaro Plaza Reyes, Sandra Petrus-Reurer, Liselotte Antonsson, Sonya Stenfelt, Hammurabi Bartuma, Sarita Panula, Theresa Mader, Iyadh Douagi, Helder André, Outi Hovatta, Fredrik Lanner, Anders Kvanta
Publikováno v:
Stem Cell Reports, Vol 6, Iss 1, Pp 9-17 (2016)
Human embryonic stem cell (hESC)-derived retinal pigment epithelial (RPE) cells could replace lost tissue in geographic atrophy (GA) but efficacy has yet to be demonstrated in a large-eyed model. Also, production of hESC-RPE has not yet been achieved
Externí odkaz:
https://doaj.org/article/20e1e75292c84e5384a548b32ba04960
Autor:
Alvaro Plaza Reyes, Sandra Petrus-Reurer, Sara Padrell Sánchez, Pankaj Kumar, Iyadh Douagi, Hammurabi Bartuma, Monica Aronsson, Sofie Westman, Emma Lardner, Helder André, Anna Falk, Emeline F. Nandrot, Anders Kvanta, Fredrik Lanner
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/5f6569547e404b8a939dfc0fd45a3443
Autor:
Paul Petrus, Niklas Mejhert, Patricia Corrales, Simon Lecoutre, Qian Li, Estela Maldonado, Agne Kulyté, Yamila Lopez, Mark Campbell, Juan R. Acosta, Jurga Laurencikiene, Iyadh Douagi, Hui Gao, Concepción Martínez-Álvarez, Per Hedén, Kirsty L. Spalding, Antonio Vidal-Puig, Gema Medina-Gomez, Peter Arner, Mikael Rydén
Publikováno v:
Cell Reports, Vol 25, Iss 3, Pp 551-560.e5 (2018)
Summary: White adipose tissue (WAT) mass is determined by adipocyte size and number. While adipocytes are continuously turned over, the mechanisms controlling fat cell number in WAT upon weight changes are unclear. Herein, prospective studies of huma
Externí odkaz:
https://doaj.org/article/9419d552f02b4179bebb20837d864c38
Autor:
Christian Scharenberg, Valentina Giai, Andrea Pellagatti, Leonie Saft, Marios Dimitriou, Monika Jansson, Martin Jädersten, Alf Grandien, Iyadh Douagi, Donna S. Neuberg, Katarina LeBlanc, Jacqueline Boultwood, Mohsen Karimi, Sten Eirik W. Jacobsen, Petter S. Woll, Eva Hellström-Lindberg
Publikováno v:
Haematologica, Vol 102, Iss 3 (2017)
A high proportion of patients with lower-risk del(5q) myelodysplastic syndromes will respond to treatment with lenalidomide. The median duration of transfusion-independence is 2 years with some long-lasting responses, but almost 40% of patients progr
Externí odkaz:
https://doaj.org/article/5bd7e8c9ce774ae4b87ffb2a0351ceb6
Autor:
Mei Ling Lim, Brandon Nick Sern Ooi, Philipp Jungebluth, Sebastian Sjöqvist, Isabell Hultman, Greg Lemon, Ylva Gustafsson, Jurate Asmundsson, Silvia Baiguera, Iyadh Douagi, Irina Gilevich, Alina Popova, Johannes Cornelius Haag, Antonio Beltrán Rodríguez, Jianri Lim, Agne Liedén, Magnus Nordenskjöld, Evren Alici, Duncan Baker, Christian Unger, Tom Luedde, Ivan Vassiliev, Jose Inzunza, Lars Ahrlund-Richter, Paolo Macchiarini
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107712 (2014)
Stem cells contribute to regeneration of tissues and organs. Cells with stem cell-like properties have been identified in tumors from a variety of origins, but to our knowledge there are yet no reports on tumor-related stem cells in the human upper r
Externí odkaz:
https://doaj.org/article/6a6e111a2f174e1eaec6898f5735aec3
Publikováno v:
Clinical and Developmental Immunology, Vol 2012 (2012)
Today, HIV-infected children who have access to treatment face a chronic rather than a progressive and fatal disease. As a result, new challenges are emerging in the field. Recent lines of evidence outline several factors that can differently affect
Externí odkaz:
https://doaj.org/article/9a7cd9065ac440f198aa2763b5cbe1d1
Autor:
Cherrelle Dacon, Courtney Tucker, Linghang Peng, Chang-Chun D. Lee, Ting-Hui Lin, Meng Yuan, Yu Cong, Lingshu Wang, Lauren Purser, Jazmean K. Williams, Chul-Woo Pyo, Ivan Kosik, Zhe Hu, Ming Zhao, Divya Mohan, Andrew J. R. Cooper, Mary Peterson, Jeff Skinner, Saurabh Dixit, Erin Kollins, Louis Huzella, Donna Perry, Russell Byrum, Sanae Lembirik, David Drawbaugh, Brett Eaton, Yi Zhang, Eun Sung Yang, Man Chen, Kwanyee Leung, Rona S. Weinberg, Amarendra Pegu, Daniel E. Geraghty, Edgar Davidson, Iyadh Douagi, Susan Moir, Jonathan W. Yewdell, Connie Schmaljohn, Peter D. Crompton, Michael R. Holbrook, David Nemazee, John R. Mascola, Ian A. Wilson, Joshua Tan
Publikováno v:
Science. 377:728-735
The potential for future coronavirus outbreaks highlights the need to broadly target this group of pathogens. We used an epitope-agnostic approach to identify six monoclonal antibodies that bind to spike proteins from all seven human-infecting corona