Exploiting Copaifera salikounda compounds as treatment against diabetes: An insight into their potential targets from a computational perspective

Autor: Aloke, Chinyere, Iwuchukwu, Emmanuel Amarachi, Achilonu, Ikechukwu

Publikováno v: In Computational Biology and Chemistry June 2023 104

Targeting the SARS-CoV-2 main protease using FDA-approved Isavuconazonium, a P2–P3 α-ketoamide derivative and Pentagastrin: An in-silico drug discovery approach

Autor: Achilonu, Ikechukwu, Iwuchukwu, Emmanuel Amarachi, Achilonu, Okechinyere Juliet, Fernandes, Manuel Antonio, Sayed, Yasien

Publikováno v: In Journal of Molecular Graphics and Modelling December 2020 101

Structure-based identification of novel scaffolds as potential HIV-1 entry inhibitors involving CCR5.

Autor: Appiah-Kubi, Patrick, Iwuchukwu, Emmanuel Amarachi, Soliman, Mahmoud E. S.

Publikováno v: Journal of Biomolecular Structure & Dynamics; Dec2022, Vol. 40 Issue 23, p13115-13126, 12p

Effect of Divalent Metal Ion on the Structure, Stability and Function of Klebsiella pneumoniae Nicotinate-Nucleotide Adenylyltransferase: Empirical and Computational Studies.

Autor: Jeje O; Protein Structure-Function Research Unit, School of Molecular and Cell Biology, Faculty of Science, University of the Witwatersrand, Johannesburg 2050, South Africa., Maake R; Protein Structure-Function Research Unit, School of Molecular and Cell Biology, Faculty of Science, University of the Witwatersrand, Johannesburg 2050, South Africa., van Deventer R; Protein Structure-Function Research Unit, School of Molecular and Cell Biology, Faculty of Science, University of the Witwatersrand, Johannesburg 2050, South Africa., Esau V; Protein Structure-Function Research Unit, School of Molecular and Cell Biology, Faculty of Science, University of the Witwatersrand, Johannesburg 2050, South Africa., Iwuchukwu EA; Protein Structure-Function Research Unit, School of Molecular and Cell Biology, Faculty of Science, University of the Witwatersrand, Johannesburg 2050, South Africa., Meyer V; Functional Genomics and Immunogenetics Laboratory, School of Molecular and Cell Biology, Faculty of Science, University of the Witwatersrand, Johannesburg 2050, South Africa., Khoza T; Department of Biochemistry, School of Life Sciences, Pietermaritzburg Campus, University of KwaZulu-Natal, Pietermaritzburg 3209, South Africa., Achilonu I; Protein Structure-Function Research Unit, School of Molecular and Cell Biology, Faculty of Science, University of the Witwatersrand, Johannesburg 2050, South Africa.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 23; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 23.