Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Iwona Wallach"'
Autor:
Agustin Liotta, Stefan Loroch, Iwona Wallach, Kristoffer Klewe, Katrin Marcus, Nikolaus Berndt
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9640 (2024)
Epilepsy is characterized by hypersynchronous neuronal discharges, which are associated with an increased cerebral metabolic rate of oxygen and ATP demand. Uncontrolled seizure activity (status epilepticus) results in mitochondrial exhaustion and ATP
Externí odkaz:
https://doaj.org/article/f55f527319044b16ae2992443d38a593
Autor:
Mehrgan Shahryari, Sarah Keller, David Meierhofer, Iwona Wallach, Yasmine Safraou, Jing Guo, Stephan R. Marticorena Garcia, Jürgen Braun, Marcus R. Makowski, Ingolf Sack, Nikolaus Berndt
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2023)
The liver is the central metabolic organ. It constantly adapts its metabolic capacity to current physiological requirements. However, the relationship between tissue structure and hepatic function is incompletely understood; this results in a lack of
Externí odkaz:
https://doaj.org/article/3613f4793683453d974e6c7469aacbab
Alterations of Central Liver Metabolism of Pediatric Patients with Non-Alcoholic Fatty Liver Disease
Autor:
Nikolaus Berndt, Christian A. Hudert, Johannes Eckstein, Christoph Loddenkemper, Stephan Henning, Philip Bufler, David Meierhofer, Ingolf Sack, Susanna Wiegand, Iwona Wallach, Hermann-Georg Holzhütter
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11072 (2022)
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in children and is associated with overweight and insulin resistance (IR). Almost nothing is known about in vivo alterations of liver metabolism in NAFLD, especially i
Externí odkaz:
https://doaj.org/article/143b69babebf49dbae451653a66c6e0b
Autor:
Mathilde Maechler, Jörg Rösner, Iwona Wallach, Joerg R. P. Geiger, Claudia Spies, Agustin Liotta, Nikolaus Berndt
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3037 (2022)
During general anesthesia, alterations in neuronal metabolism may induce neurotoxicity and/or neuroprotection depending on the dose and type of the applied anesthetic. In this study, we investigate the effects of clinically relevant concentrations of
Externí odkaz:
https://doaj.org/article/f709b429517b426aa4a5adb9dbe18bde
Autor:
Nikolaus Berndt, Sascha Bulik, Iwona Wallach, Tilo Wünsch, Matthias König, Martin Stockmann, David Meierhofer, Hermann-Georg Holzhütter
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
In silico models of cells can provide insight into the causes and effects of disease states and reduce the need for in vivo studies. Here, the authors present a kinetic model of hepatocyte metabolism including energy, carbohydrate, lipid and nitrogen
Externí odkaz:
https://doaj.org/article/77be495539204df281e2112ebf72702b
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 3977 (2020)
Multimodal continuous bedside monitoring is increasingly recognized as a promising option for early treatment stratification in patients at risk for ischemia during neurocritical care. Modalities used at present are, for example, oxygen availability
Externí odkaz:
https://doaj.org/article/3fca6db2b9e0482d99f5c2443c72d452
Autor:
Tatsuya Akutsu, Minoru Kanehisa, Edda Klipp, Satoru Miyano, Scott Mohr, Thomas Tullius, Iwona Wallach
This volume contains 18 peer-reviewed papers based on the presentations at the 10th Annual International Workshop on Bioinformatics and Systems Biology (IBSB 2010) held at Kyoto University from July 26 to July 28, 2010. This workshop started in 2001
Autor:
Anja Hennemuth, Iwona Wallach, Leonid Goubergrits, Tilman Grune, Marie Schafstedde, Nikolaus Berndt, Philipp Mertins, Johannes Eckstein, Titus Kuehne, Milena Kraus, Sarah Nordmeyer, Marieluise Kirchner, Hermann-Georg Holzhütter, Marcus Kelm
Publikováno v:
Circulation
Supplemental Digital Content is available in the text.
Background: Many heart diseases can result in reduced pumping capacity of the heart muscle. A mismatch between ATP demand and ATP production of cardiomyocytes is one of the possible causes.
Background: Many heart diseases can result in reduced pumping capacity of the heart muscle. A mismatch between ATP demand and ATP production of cardiomyocytes is one of the possible causes.
Autor:
Zoltan Gerevich, Richard Kovács, Agustin Liotta, Luisa A Hasam-Henderson, Ludwig Weh, Iwona Wallach, Nikolaus Berndt
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. :0271678X2311707
Myelination enhances the conduction velocity of action potentials (AP) and increases energy efficiency. Thick myelin sheaths are typically found on large-distance axonal connections or in fast-spiking interneurons, which are critical for synchronizin
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3977, p 3977 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 11
International Journal of Molecular Sciences
Volume 21
Issue 11
Multimodal continuous bedside monitoring is increasingly recognized as a promising option for early treatment stratification in patients at risk for ischemia during neurocritical care. Modalities used at present are, for example, oxygen availability