Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Iwona Siuda"'
Autor:
Valentina Corradi, Eduardo Mendez-Villuendas, Helgi I. Ingólfsson, Ruo-Xu Gu, Iwona Siuda, Manuel N. Melo, Anastassiia Moussatova, Lucien J. DeGagné, Besian I. Sejdiu, Gurpreet Singh, Tsjerk A. Wassenaar, Karelia Delgado Magnero, Siewert J. Marrink, D. Peter Tieleman
Publikováno v:
ACS Central Science, Vol 4, Iss 6, Pp 709-717 (2018)
Externí odkaz:
https://doaj.org/article/db97d572cfee429aa2cca91ede5193a4
Autor:
Todd L. Lowary, Justin B. Renaud, Michele R. Richards, Elena N. Kitova, Paul M. Mayer, John S. Klassen, Lan Liu, D. Peter Tieleman, Iwona Siuda
Publikováno v:
ChemBioChem. 17:1571-1578
We report a detailed study of the structure and stability of carbohydrate-lipid interactions. Complexes of a methylmannose polysaccharide (MMP) derivative and fatty acids (FAs) served as model systems. The dependence of solution affinities and gas-ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3818dee1f47ad4350ed0b48960dda493
https://doi.org/10.1002/cbic.201600123
https://doi.org/10.1002/cbic.201600123
Autor:
Iwona Siuda, Tsjerk A. Wassenaar, Valentina Corradi, Siewert J. Marrink, Anastassiia Moussatova, Besian I. Sejdiu, Eduardo Mendez-Villuendas, Karelia Hortencia Delgado Magnero, D. Peter Tieleman, Lucien J. DeGagné, Manuel N. Melo, Helgi I. Ingólfsson, Ruo-Xu Gu, Gurpreet Singh
Publikováno v:
ACS Central Science
ACS central science, 4(6), 709-717. AMER CHEMICAL SOC INC
ACS Central Science, Vol 4, Iss 6, Pp 709-717 (2018)
ACS central science, 4(6), 709-717. AMER CHEMICAL SOC INC
ACS Central Science, Vol 4, Iss 6, Pp 709-717 (2018)
Cell membranes contain hundreds of different proteins and lipids in an asymmetric arrangement. Our current understanding of the detailed organization of cell membranes remains rather elusive, because of the challenge to study fluctuating nanoscale as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79de7a4ee2087ed3bd35fb74787f8b00
Autor:
Iwona Siuda, D. Peter Tieleman
Publikováno v:
Journal of chemical theory and computation. 11(10)
Nanodiscs are discoloidal protein–lipid particles that self-assemble from a mixture of lipids and membrane scaffold proteins. They form a highly soluble membrane mimetic that closely resembles a native-like lipid environment, unlike micelles. Nanod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3391c7b2fec77f8b21f1058fa21d49f
https://pubmed.ncbi.nlm.nih.gov/26574280
https://pubmed.ncbi.nlm.nih.gov/26574280
Autor:
Poul Nissen, Yonathan Sonntag, Henriette Elisabeth Autzen, Jesper V. Møller, Lea Thøgersen, Iwona Siuda
Publikováno v:
Autzen, H E, Siuda, I, Sonntag, Y, Nissen, P, Møller, J V & Thøgersen, L 2015, ' Regulation of the Ca(2+)-ATPase by cholesterol : A specific or non-specific effect? ', Molecular Membrane Biology, vol. 32, no. 3, pp. 75-87 . https://doi.org/10.3109/09687688.2015.1073382
Like other integral membrane proteins, the activity of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) is regulated by the membrane environment. Cholesterol is present in the endoplasmic reticulum membrane at low levels, and it has the potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::692618822a6bc07fb0f5d7a2016a073d
Autor:
Lea Thøgersen, Iwona Siuda
Publikováno v:
Siuda, I & Thøgersen, L 2013, ' Conformational flexibility of the leucine binding protein examined by protein domain coarse-grained molecular dynamics ', Journal of Molecular Modeling, vol. 19, no. 11, pp. 4931-4945 . https://doi.org/10.1007/s00894-013-1991-9
Periplasmic binding proteins are the initial receptors for the transport of various substrates over the inner membrane of gram-negative bacteria. The binding proteins are composed of two domains, and the substrate is entrapped between these domains.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b540bea9615eff2ac9e72e7c5a23d5
https://pubmed.ncbi.nlm.nih.gov/24048570
https://pubmed.ncbi.nlm.nih.gov/24048570
An Elastic Network Coarse Grained MD Model Tested on Protein with Hinge Movement upon Ligand Binding
Autor:
Iwona Siuda, Lea Thøgersen
Publikováno v:
Biophysical Journal. 102(3)
In recent years, coarse grained (CG) models, with a resolution at the residue level for proteins,1,2 have gained great popularity, due to its balance between accessible time scale and detail level. However, because of the coarse description of the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0384fc0beb850c11dc4392594fa2afe8
Autor:
Lea Thøgersen, Iwona Siuda
Publikováno v:
Biophysical Journal. 100(3)
Many biologically interesting phenomena occur on a time scale which is out of reach for atomistic molecular dynamics simulations, therefore coarse grained (CG) description of the system is applied. In recent years, CG models, with a resolution at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa668f0db3f9339db8b9f1906a7bda2
Publikováno v:
Biophysical Journal. 106:51a
NK-lysin and the saposins A, C, and D are proteins belonging to the saposin-like family. They are small, nonenzymatic, heat-stable lysosomal proteins essential for the degradation of sphingolipids and lipid antigen presentation. For both the soluble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62cc7371283956f5f51721451570395
https://doi.org/10.1016/j.bpj.2013.11.363
https://doi.org/10.1016/j.bpj.2013.11.363
Autor:
D. Peter Tieleman, Iwona Siuda
Publikováno v:
Biophysical Journal. (2):467a
In recent years an engineered form of discoloidal high-density lipoprotein particle, called nanodisc, has been proposed as a platform to study membrane proteins. A nanodisc is a non-covalent assembly of phospholipids and two membrane scaffold protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::998765c4b72b83ad1a53fe7f34017b8b