Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Iwona Papla"'
Publikováno v:
Behavioral Pharmacology. 12:109-116
Recent studies have shown that antagonists of serotonin (5-HT)1B receptors attenuate cocaine-induced locomotor hyperactivity, whereas agonists enhance reinforcing and discriminative stimulus effects of the psychostimulant. The present study was desig
Autor:
Jerzy Michaluk, Andrzej Szczudlik, Jerzy Vetulani, M. Bakalarz, Iwona Papla, Irena Romańska, Anna Krygowska-Wajs, Lucyna Antkiewicz-Michaluk
Publikováno v:
Neuroscience. 96:59-64
The finding that endogenous tetrahydroisoquinolines may be involved in the etiology of Parkinson's disease suggests that their administration may cause changes resembling those observed in parkinsonian brain. We tested, using a high-performance liqui
Autor:
Edmund Przegaliński, Iwona Papla, Małgorzata Frankowska, Magdalena Zaniewska, Małgorzata Filip
Publikováno v:
Neuropeptides. 39(5)
We examined the influence of CP 154,526, a selective antagonist of corticotropin-releasing factor (CRF)1 receptors, in the locomotor, sensitizing, discriminative stimulus and rewarding effects of cocaine, as well as on the cocaine-induced reinstateme
Autor:
Irena Romańska, Antoni Patsenka, Jerzy Vetulani, Edmund Przegaliński, Lucyna Antkiewicz-Michaluk, Jerzy Michaluk, Małgorzata Filip, Iwona Papla
Publikováno v:
The international journal of neuropsychopharmacology. 9(1)
Craving phenomena are related to induction of substance-seeking behaviour by stimuli associated with the availability of the drug. We investigated the changes in monoamine metabolism in regions of the brains of rats that, following a period of traini
Publikováno v:
Polish journal of pharmacology. 55(6)
In the present study, we attempted to determine the effects of an atypical antipsychotic drug clozapine on the locomotor activation as well as sensitization to cocaine in male Wistar rats. When given acutely to rats, cocaine (10 mg/kg, ip) increased
Publikováno v:
Polish journal of pharmacology. 54(6)
It is established that dopamine (DA) is an important brain mediator of the behavioral (i.e. sensitizing) effects of cocaine in rodents. Among DA receptors, recent findings point to engagement of DA D3 receptors in cocaine addictive actions. In the pr
Publikováno v:
Polish journal of pharmacology. 54(4)
Previous research demonstrated that the mesoaccumbens dopamine (DA) pathway played a critical role in the behavioral effects of amphetamine in rodents. Nonetheless, recent findings have also indicated involvement of 5-hydroxytryptamine (5-HT, seroton
Publikováno v:
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 14(3)
The present study was aimed at finding out whether 5-HT(1B) receptors located in the ventral tegmental area (VTA) played a role in the locomotor hyperactivity induced by a single dose of cocaine and in the sensitization evoked by repeated exposure to
Publikováno v:
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 12(5)
The present study was designed to find out whether 5-HT(1B) receptors located in subareas of the nucleus accumbens played a role in cocaine sensitization in rats, and whether pharmacological activation of these receptors could modify this drug effect
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 366(3)
Recent data indicate a significant input of serotonin (5-HT) on mesoaccumbens dopamine-dependent behavioral effects of cocaine in rats. The present study investigated the role of 5-HT(1B) receptors in nucleus accumbens subregions (the shell and the c