Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Iwona Osinska"'
Autor:
Dariusz Dziedzic, Anna Stelmaszczyk-Emmel, Małgorzata Polubiec-Kownacka, Iwona Osinska, Joanna Domagała-Kulawik
Publikováno v:
Human Immunology. 77:912-915
The aim of the study was to compare the presence of regulatory T cells (Tregs) in the local lung cancer environment versus systemic immune response based on the examination of bronchoalveolar lavage fluid (BALf) and peripheral blood (PB) from the sam
Publikováno v:
Central-European Journal of Immunology
The role of bronchoalveolar lavage fluid (BALf) examination in differential diagnosis of interstitial lung diseases (ILD) was established. Currently, functional polarization into M1 (pro-inflammatory) and M2 (anti-inflammatory) subpopulations is emph
Autor:
Joanna Domagała-Kulawik, Iwona Osinska
Publikováno v:
Advances in Respiratory Medicine. 82:286-299
Lung cancer is the main cause of cancer death worldwide. An advanced stage of the disease at the time of diagnosis, observed in the majority of cases, does not allow for introduction of radical treatment or makes the treatment ineffective. Lung cance
Publikováno v:
Central-European Journal of Immunology
Perforin is a glycoprotein responsible for pore formation in cell membranes of target cells. Perforin is able to polymerize and form a channel in target cell membrane. Many research groups focus on the role of perforin in various diseases, immune res
Autor:
Urszula Demkow, Katarzyna Popko, Elżbieta Górska, Iwona Malinowska, Anna Kucharska, Iwona Osinska, Marta Rychta
Publikováno v:
Central European Journal of Immunology. 4:562-568
Natural killer (NK) cells account for up to 15% of all peripheral blood lymphocytes and are characterized phenotypically by the presence of CD56/CD16 antigens and the lack of CD3 antigen. Natural killer cells exert cytotoxic functions against a varie
Autor:
Magorzata Proboszcz, Magorzata Polubiec-Kownacka, Joanna Domagaa-Kulawik, Dariusz Dziedzic, Iwona Osinska, Dominika Wolosz
Publikováno v:
ERS Lung Science Conference 2016.
The biomarkers as potential predictive factors for immunotherapy are recently widely investigated. Macrophages play an important role in suppression of immune anti- cancer response. It is known that M2 macrophages are predominant in resected tumors b
Autor:
Dariusz Dziedzic, Dominika Wolosz, Iwona Osinska, Małgorzata Polubiec-Kownacka, Małgorzata Proboszcz, Joanna Domagała-Kulawik
Publikováno v:
11.1 Lung Cancer.
Macrophages M2 play a role in suppression of immune anticancer response and that the predominance of M2 was found in resected tumors. However little is known about macrophage polarization in advanced stages of cancer, in which the immune response may
Autor:
Małgorzata Polubiec-Kownacka, Iwona Osinska, Joanna Domagała-Kulawik, Dariusz Dziedzic, Anna Stelmaszczyk-Emmel, Małgorzata Proboszcz
Publikováno v:
11.1 Lung Cancer.
There are many mechanisms that allow to escape tumour cells from immune surveillance. It is known that T regulatory cells (Tregs) play a crucial role in the inhibition of immune response. Th17 cells are defined by production of IL17A and have pleiotr
Autor:
Małgorzata Polubiec-Kownacka, Anna Stelmaszczyk-Emmel, Iwona Osinska, Joanna Domagała-Kulawik, Dariusz Dziedzic
Publikováno v:
11.1 Lung Cancer.
Many mechanisms of immune response have been demonstrated in lung cancer patients in circulation and resected tumor samples. The investigation of possible biomarkers before immunomodulatory treatment are ongoing. We postulate the usefulness of examin
Autor:
Monika Pasieka-Lis, Dominika Wolosz, Iwona Osinska, Joanna Domagała-Kulawik, Juliusz Pankowski
Publikováno v:
11.1 Lung Cancer.
A balance between tumour invasion and immune defence system is widely investigated. The aim of study was to evaluate lymphocyte phenotype and the expression of FoxP3 in lymph nodes (LN) of patients with lung cancer in relation to presence of metastas