Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Iwona Matuszczyk"'
Autor:
Ewa Grzybowska, Marek Rusin, Małgorzata Krześniak, Jadwiga Rachtan, Dorota Butkiewicz, Iwona Matuszczyk
Publikováno v:
Advances in Medical Sciences. 62:207-210
Purpose Li-Fraumeni syndrome (LFS) is a rare genetic disease with strong predispositions to multiple early-onset neoplasms, mostly sarcomas, breast cancers, brain tumors and adrenocortical carcinomas (LFS core cancers). In most LFS families the germl
Publikováno v:
Mechanisms of ageing and development. 139
The activation of the p53 pathway by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR), a molecule that mimics metabolic stress, is attenuated by rapamycin, an inhibitor of mTOR kinase, immunosuppressant, and cancer drug. Rapamycin also extends l
Autor:
Marek Rusin, Agata Kosarewicz, Małgorzata Krześniak, Anna Drosik, M. Gawkowska-Suwinska, Dorota Butkiewicz, Iwona Matuszczyk, Jadwiga Rachtan, Rafał Suwiński
Publikováno v:
International journal of cancer. 131(7)
Polymorphisms in DNA repair genes may modulate not only an individual DNA repair capacity, DNA damage levels and cancer risk but also clinical outcome after DNA damage-inducing anticancer therapy. In this study, we analyzed the association between th
Autor:
Marek Rusin, Małgorzata Krześniak, Artur Zajkowicz, Magdalena Głowala-Kosińska, Dorota Butkiewicz, Iwona Matuszczyk
Publikováno v:
Molecular Biology Reports
Resveratrol is a natural compound that has been intensely studied due to its role in cancer prevention and potential as an anti-cancer therapy. Its effects include induction of apoptosis and senescence-like growth inhibition. Here, we report that two