Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Iwona M Konieczna"'
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111943 (2014)
The cellular immune response is the most important mediator of allograft rejection and is a major barrier to transplant tolerance. Delineation of the depth and breadth of the alloreactive T cell repertoire and subsequent application of the technology
Externí odkaz:
https://doaj.org/article/8b2c3d00c51941f385111750b77d0827
Autor:
Agnieszka I. Laskowski, Daniel S. Neems, Kyle Laster, Chelsee Strojny-Okyere, Ellen L. Rice, Iwona M. Konieczna, Jessica H. Voss, James M. Mathew, Joseph R. Leventhal, Rosalind Ramsey-Goldman, Erica D. Smith, Steven T. Kosak
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Abstract The three-dimensional organization of the genome in mammalian interphase nuclei is intrinsically linked to the regulation of gene expression. Whole chromosome territories and their encoded gene loci occupy preferential positions within the n
Externí odkaz:
https://doaj.org/article/f3f068a3414d4bb58406abd7df6067b9
Autor:
PK Epling-Burnette, Durga B Dandamudi, Iwona M Konieczna, Kelly M Calabrese, Monica Wielgos-Bonvallet, Christiaan Kweekel, Elke Gresnigt - van den Heuvel, Apurvasena Parikh, Tommy Li, Christopher W Chiu, Adam Chervin, Edward B Reilly, Edith Szafer-Glusman
Publikováno v:
Blood. 140:9283-9285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4666a33b5618e57d65ebe2796c467b3
https://doi.org/10.1182/blood-2022-162538
https://doi.org/10.1182/blood-2022-162538
Autor:
Daniel S. Neems, Agnieszka I. Laskowski, James M. Mathew, Rosalind Ramsey-Goldman, Ellen L. Rice, Iwona M. Konieczna, Chelsee Strojny-Okyere, Steven T. Kosak, Jessica H. Voss, Joseph R. Leventhal, Kyle Laster, Erica D. Smith
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
The three-dimensional organization of the genome in mammalian interphase nuclei is intrinsically linked to the regulation of gene expression. Whole chromosome territories and their encoded gene loci occupy preferential positions within the nucleus th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c1acf461487cb8833d1dfe0a2abc1c
https://doaj.org/article/f3f068a3414d4bb58406abd7df6067b9
https://doaj.org/article/f3f068a3414d4bb58406abd7df6067b9
Autor:
Steven T. Kosak, Kyle Laster, Jessica H. Voss, Ellen L. Rice, Erica D. Smith, James Mathew, Joseph R. Leventhal, Agnieszka I. Laskowski, Rosalind Ramsey-Goldman, Iwona M. Konieczna, Chelsee Strojny-Okyere, Daniel S. Neems
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
Scientific Reports
Scientific Reports
The three-dimensional organization of the genome in mammalian interphase nuclei is intrinsically linked to the regulation of gene expression. Whole chromosome territories and their encoded gene loci occupy preferential positions within the nucleus th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133c5b1e0d883a2d46a1b6e0203d4211
https://doi.org/10.1038/s41598-019-51828-z
https://doi.org/10.1038/s41598-019-51828-z
Publikováno v:
British Journal of Haematology. 173:303-313
The transcription factor HOXA10 is an important regulator of myelopoiesis. Engineered over-expression of Hoxa10 in mice results in a myeloproliferative disorder that progresses to acute myeloid leukaemia (AML) over time, and in humans over-expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ecc4c25a67248c95240126aec4d7e20
https://doi.org/10.1111/bjh.13949
https://doi.org/10.1111/bjh.13949
Autor:
Lorenzo Gallon, Mohammed Javeed I. Ansari, James M. Mathew, Xuemei Huang, Jie He, Jessica H. Voss, Joseph R. Leventhal, Ann V. LeFever, Iwona M. Konieczna, Anton I. Skaro, Cheryl Stratton
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
There is considerable interest in therapeutic transfer of regulatory T cells (Tregs) for controlling aberrant immune responses. Initial clinical trials have shown the safety of Tregs in hematopoietic stem cell transplant recipients and subjects with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1601342bb6596f16b871cf24f031aac
https://doi.org/10.1038/s41598-018-25574-7
https://doi.org/10.1038/s41598-018-25574-7
Autor:
Xuemei Huang, Scott T. McEwen, Arjun Chakraborty, Jessica H. Voss, Iwona M. Konieczna, Joseph R. Leventhal, Lorenzo Gallon, Jie He, Richard S. Kornbluth, James M. Mathew
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Donor-specific CD4+CD127−CD25+FOXP3+ regulatory T cells (AgTregs) have the potential to induce clinical transplant tolerance; however, their expansion ex vivo remains challenging. We optimized a novel expansion protocol to stimulate donor-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d401d09d542167adc6fa402235d0890
http://europepmc.org/articles/PMC5773708
http://europepmc.org/articles/PMC5773708
Autor:
James M. Mathew, Joseph R. Leventhal, Iwona M. Konieczna, Esma S. Yolcu, Michael Abecassis, Jayesh Mehta, Joshua Miller, Larry D. Bozulic, Michael G. Ison, David J. Tollerud, Suzanne T. Ildstad, Mark D. Badder, Mary Jane Elliott, John P. Galvin, Lorenzo Gallon
Publikováno v:
Transplantation. 99:288-298
Nineteen subjects have more than 18 months' follow-up in a phase IIb tolerance protocol in HLA-mismatched recipients of living donor kidney plus facilitating cell enriched hematopoietic stem cell allografts (FCRx). Reduced intensity conditioning prec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb008a6febf86b43ae54a95452e9aa0
https://doi.org/10.1097/tp.0000000000000605
https://doi.org/10.1097/tp.0000000000000605
Autor:
Elizabeth A. Eklund, Gurveen Saberwal, Wei Zhou, Iwona M. Konieczna, Leonidas C. Platanias, Efstratios Katsoulidis, Weiqi Huang, Elizabeth Horvath
Publikováno v:
Molecular and Cellular Biology. 30:4575-4594
The interferon consensus sequence binding protein (ICSBP) is an interferon regulatory transcription factor, also referred to as IRF8. ICSBP acts as a suppressor of myeloid leukemia, although few target genes explaining this effect have been identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab08d1e3ae0c85e7944f2a9990a0bd3
https://doi.org/10.1128/mcb.01595-09
https://doi.org/10.1128/mcb.01595-09