Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Iwona Czaban"'
Autor:
Vladlena Kharchenko, Brian M. Linhares, Megan Borregard, Iwona Czaban, Jolanta Grembecka, Mariusz Jaremko, Tomasz Cierpicki, Łukasz Jaremko
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Here, the authors discover that ligandability of BTB domains correlates with the presence of μs-ms time scale dynamics. This finding suggests that protein dynamics may be a broadly applicable tool in drug discovery to assess the ligandability of nov
Externí odkaz:
https://doaj.org/article/aa28f8e109144ab989d8e1e2a1ebf07b
Autor:
Anna Skupien-Jaroszek, Agnieszka Walczak, Iwona Czaban, Katarzyna Karolina Pels, Andrzej Antoni Szczepankiewicz, Katarzyna Krawczyk, Błażej Ruszczycki, Grzegorz Marek Wilczynski, Joanna Dzwonek, Adriana Magalska
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0239111 (2021)
The Brain-Derived Neurotrophic Factor is one of the most important trophic proteins in the brain. The role of this growth factor in neuronal plasticity, in health and disease, has been extensively studied. However, mechanisms of epigenetic regulation
Externí odkaz:
https://doaj.org/article/d596a654b77a4c9c812038c27972a15b
Autor:
Mateusz G. Adamski, Magdalena Sternak, Tasnim Mohaissen, Dawid Kaczor, Joanna M. Wierońska, Monika Malinowska, Iwona Czaban, Katarzyna Byk, Kristina S. Lyngsø, Kamil Przyborowski, Pernille B.L. Hansen, Grzegorz Wilczyński, Stefan Chlopicki
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 7 (2018)
BackgroundAlthough advanced heart failure (HF) is a clinically documented risk factor for vascular cognitive impairment, the occurrence and pathomechanisms of vascular cognitive impairment in early stages of HF are equivocal. Here, we characterize va
Externí odkaz:
https://doaj.org/article/b7c4a58aea5d4c42b9545c59acc5bee1
Autor:
Agnieszka Grabowska, Hanna Sas-Nowosielska, Bartosz Wojtas, Dagmara Holm-Kaczmarek, Elzbieta Januszewicz, Yana Yushkevich, Iwona Czaban, Pawel Trzaskoma, Katarzyna Krawczyk, Bartlomiej Gielniewski, Ana Martin-Gonzalez, Robert Kuba Filipkowski, Krzysztof Hubert Olszynski, Tytus Bernas, Andrzej Antoni Szczepankiewicz, Malgorzata Alicja Sliwinska, Tambudzai Kanhema, Clive R. Bramham, Grzegorz Bokota, Dariusz Plewczynski, Grzegorz Marek Wilczynski, Adriana Magalska
Publikováno v:
Cell reports
Spatial chromatin organization is crucial for transcriptional regulation and might be particularly important in neurons since they dramatically change their transcriptome in response to external stimuli. We show that stimulation of neurons causes con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de8c1f567690cfd64eb395adfbd0f89
http://hdl.handle.net/10261/286088
http://hdl.handle.net/10261/286088
Publikováno v:
Journal of Inorganic Biochemistry. 191:69-76
Islet Amyloid Polypeptide (IAPP), also known as amylin, is a 37-amino-acid peptide hormone that is secreted by pancreatic islet β-cells. Amylin is complementary to insulin in regulating and maintaining blood glucose levels in the human body. The mis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107545dba008fb26939d95ee531f7a2a
https://doi.org/10.1016/j.jinorgbio.2018.11.004
https://doi.org/10.1016/j.jinorgbio.2018.11.004
Autor:
Simone Hausmann, Iwona Czaban, Natasha M. Flores, John D. Minna, Katrin F. Chua, Mariusz Jaremko, Pawel K. Mazur, Dulat Azhibek, Silvestre Vicent, Gang Yuan, Xiaoyin Lu, Ignacio I. Wistuba, Deepanwita Sengupta, Łukasz Jaremko, Ning-Yi Shao, Wolfgang Fischle, Maria Angulo-Ibanez, Jack A. Roth, Vladlena Kharchenko, Or Gozani, Shane Lofgren, Bingliang Fang
Publikováno v:
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
Nature
instname
Nature
Amplification of chromosomal region 8p11–12 is a common genetic alteration that has been implicated in the aetiology of lung squamous cell carcinoma (LUSC)1–3. The FGFR1 gene is the main candidate driver of tumorigenesis within this region4. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59c0bad13ecf7cd74c843b53dcff8de
https://hdl.handle.net/10171/62052
https://hdl.handle.net/10171/62052
Autor:
Andrzej A. Szczepankiewicz, Agnieszka Walczak, Katarzyna Karolina Pels, Iwona Czaban, Grzegorz M. Wilczynski, Adriana Magalska, Katarzyna Krawczyk, Blazej Ruszczycki, Joanna Dzwonek, Anna Skupien-Jaroszek
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0239111 (2021)
PLoS ONE
PLoS ONE
The Brain-Derived Neurotrophic Factor is one of the most important trophic proteins in the brain. The role of this growth factor in neuronal plasticity, in health and disease, has been extensively studied. However, mechanisms of epigenetic regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51020395754a11c2d34836538c25066
https://doaj.org/article/d596a654b77a4c9c812038c27972a15b
https://doaj.org/article/d596a654b77a4c9c812038c27972a15b
Autor:
Hanna Sas-Nowosielska, Malgorzata Alicja Sliwinska, Krzysztof H. Olszyński, Pawel Trzaskoma, Iwona Czaban, Dagmara Holm-Kaczmarek, Grzegorz Bokota, Agnieszka Grabowska, Katarzyna Krawczyk, Bartlomiej Gielniewski, Robert K. Filipkowski, Bartosz Wojtas, Ana Martin-Gonzalez, Dariusz Plewczynski, Adriana Magalska, Grzegorz M. Wilczynski, Elzbieta Januszewicz, Tytus Bernas, Clive R. Bramham, Yana Yushkevich, Andrzej Antoni Szczepankiewicz, Tambudzai Kanhema
Publikováno v:
SSRN Electronic Journal.
Spatial chromatin organization is crucial for transcriptional regulation and might therefore be particularly dynamic in neurons since these terminally differentiated cells dramatically change their transcriptome in response to external stimuli. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9cdf70d61f808b3c8f9a840b765c14f
https://doi.org/10.2139/ssrn.3802029
https://doi.org/10.2139/ssrn.3802029
Autor:
Joanna Dzwonek, Grzegorz M. Wilczynski, Adriana Magalska, Blazej Ruszczycki, Iwona Czaban, Anna Skupien, Agnieszka Walczak, Andrzej A. Szczepankiewicz, Katarzyna Karolina Pels, Katarzyna Krawczyk
Brain-Derived Neurotrophic Factor is one of the most important trophic proteins in the brain. The role of this growth factor in neuronal plasticity, in health and disease, has been extensively studied. However, mechanisms of epigenetic regulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f725decd8727d179e2afb565b20bd00c
https://doi.org/10.1101/2020.09.01.277327
https://doi.org/10.1101/2020.09.01.277327
Autor:
Garry L. Coles, Julien Sage, Deepanwita Sengupta, Łukasz Jaremko, Thuyen Nguyen, Pawel K. Mazur, Vladlena Kharchenko, Marcello Caporicci, Ana Morales Benitez, Iwona Czaban, Debopam Ghosh, Or Gozani, Liyong Zeng, Simone Hausmann, Dulat Azhibek, Ignacio I. Wistuba, Mariusz Jaremko, Wolfgang Fischle, Yumei Li, Wei Li, Gang Yuan, Ruitu Lyu
Publikováno v:
Mol Cell
Summary The etiological role of NSD2 enzymatic activity in solid tumors is unclear. Here we show that NSD2, via H3K36me2 catalysis, cooperates with oncogenic KRAS signaling to drive lung adenocarcinoma (LUAD) pathogenesis. In vivo expression of NSD2E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa2b593b6f3c847ae00e1119dd4795a
https://doi.org/10.1016/j.molcel.2021.08.034
https://doi.org/10.1016/j.molcel.2021.08.034