Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Iwona A. Cymerman"'
Autor:
Agata Gozdz, Oleksii Nikolaienko, Malgorzata Urbanska, Iwona A. Cymerman, Ewa Sitkiewicz, Magdalena Blazejczyk, Michal Dadlez, Clive R. Bramham, Jacek Jaworski
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
The selective and neuronal activity-dependent degradation of synaptic proteins appears to be crucial for long-term synaptic plasticity. One such protein is activity-regulated cytoskeleton-associated protein (Arc), which regulates the synaptic content
Externí odkaz:
https://doaj.org/article/32506f9bfb8441bba8f6fb0530058634
Autor:
Iwona A Cymerman, Agata Gozdz, Malgorzata Urbanska, Jacek Milek, Magdalena Dziembowska, Jacek Jaworski
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134018 (2015)
Although memories appear to be elusive phenomena, they are stored in the network of physical connections between neurons. Dendritic spines, which are actin-rich dendritic protrusions, serve as the contact points between networked neurons. The spines'
Externí odkaz:
https://doaj.org/article/8366ba1af1d7425fbe257807dd314bab
Autor:
Iwona A. Cymerman, Fred Van Leuven, Malgorzata Urbanska, Agata Gozdz, Matylda Macias, Herman Devijver, Ilona Kondratiuk, Ewa Liszewska, Jacek Jaworski, Benoit Lechat
Publikováno v:
Molecular Neurobiology. 55:6050-6062
Glycogen synthase kinases-3β (GSK3β) is a key regulator of cell homeostasis. In neurons, GSK3β contributes to control of neuronal transmission and plasticity. Despite extensive studies in non-neuronal cells, crosstalk between GSK3β and other sign
Autor:
Katarzyna Kamińska, David A. Campbell, Maria Werner, Bidyottam Mittra, Iwona A. Cymerman, Elzbieta Purta, Jacek Jaworski, Janusz M. Bujnicki, Jesse R. Zamudio, Nancy R. Sturm
Publikováno v:
Nucleic Acids Research
The 5' cap of human messenger RNA consists of an inverted 7-methylguanosine linked to the first transcribed nucleotide by a unique 5'-5' triphosphate bond followed by 2'-O-ribose methylation of the first and often the second transcribed nucleotides,
Autor:
Leszek Kaczmarek, Iwona A. Cymerman, Szymon Łęski, Magdalena Jasińska, Magdalena Dziembowska, Jacek Milek
Publikováno v:
Molecular Neurobiology
Mir-132 is a neuronal activity-regulated microRNA that controls the morphology of dendritic spines and neuronal transmission. Similar activities have recently been attributed to matrix metalloproteinase-9 (MMP-9), an extrasynaptic protease. In the pr
Publikováno v:
Protein Science. 16:82-91
Lysosomal DNase IIalpha is essential for DNA waste removal and auxiliary apoptotic DNA fragmentation in higher eukaryotes. Despite the key role of this enzyme, little is known about its structure-function relationships. Here, mutational and biochemic
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 65:867-876
The restriction endonuclease (REase) R. HphI is a Type IIS enzyme that recognizes the asymmetric target DNA sequence 5'-GGTGA-3' and in the presence of Mg(2+) hydrolyzes phosphodiester bonds in both strands of the DNA at a distance of 8 nucleotides t
Autor:
Katarzyna Piwocka, Piotr Widlak, Grazyna Mosieniak, Adriana Magalska, Anna Bielak-Zmijewska, Iwona A. Cymerman, Ewa Sikora, Janusz M. Bujnicki, Magdalena Kalinowska
Publikováno v:
Molecular Cancer Therapeutics. 5:927-934
Curcumin is a natural pigment that has been shown to induce cell death in many cancer cells; however, the death mode depends on the cell type and curcumin concentration. Here we show that, in Jurkat cells, 50 μmol/L curcumin severely lowers cell sur
Publikováno v:
Bioinformatics. 21:3959-3962
Motivation: DNase II is an endodeoxyribonuclease involved in apoptosis and essential for the mammalian development. Despite the understanding of biochemical properties of this enzyme, its structure and relationships to other protein families remain u
Autor:
Joanna M. Sasin, Janusz M. Bujnicki, Marcin Feder, Jan Kosinski, Iwona A. Cymerman, Michal A. Kurowski
Publikováno v:
Proteins: Structure, Function, and Genetics. 53:369-379
We applied a new multi-step protocol to predict the structures of all targets during CASP5, regardless of their potential category. 1) We used diverse fold-recognition (FR) methods to generate initial target-template alignments, which were converted