Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Iwona, Radziejewska"'
Autor:
Iwona Radziejewska
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116619- (2024)
Glycosylation of cancerous epithelial MUC1 protein is specifically altered in comparison to that which is presented by healthy cells. One of such changes is appearing tumor-associated carbohydrate antigens (TACAs) which are rare in normal tissues and
Externí odkaz:
https://doaj.org/article/8d5816d2059247e08220bfbcc0a46a2d
Autor:
Iwona Radziejewska, Katarzyna Supruniuk, Katarzyna Jakimiuk, Michał Tomczyk, Anna Bielawska, Anna Galicka
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13036 (2023)
Specific changes in mucin-type O-glycosylation are common for many cancers, including gastric ones. The most typical alterations include incomplete synthesis of glycan structures, enhanced expression of truncated O-glycans (Tn, T antigens and their s
Externí odkaz:
https://doaj.org/article/dea45cdf8e3b499baebad529329b5e7a
Publikováno v:
Translational Oncology, Vol 18, Iss , Pp 101348- (2022)
The membrane-bound MUC1 mucin is overexpressed and aberrantly glycosylated in many epithelium origin cancers. One of the promising strategies in cancer therapy is combining monoclonal antibodies against cancer related antigens, like MUC1, with chemot
Externí odkaz:
https://doaj.org/article/9517b4d4367a4c07b3870fd51e706c5d
Autor:
Iwona Radziejewska, Katarzyna Supruniuk, Michał Tomczyk, Wiktoria Izdebska, Małgorzata Borzym-Kluczyk, Anna Bielawska, Krzysztof Bielawski, Anna Galicka
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8602 (2022)
Abnormal glycosylation of cancer cells is considered a key factor of carcinogenesis related to growth, proliferation, migration and invasion of tumor cells. Many plant-based polyphenolic compounds reveal potential anti-cancer properties effecting cel
Externí odkaz:
https://doaj.org/article/fdfd6bf55f274765ab92146dadcabead
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 973 (2021)
Afzelin demonstrates anti-inflammatory and anti-cancer properties. Our purpose was to assess its influence on apoptosis, Bax, caspases, MUC1, cancer-related carbohydrate antigens, enzymes participating in their formation, and galectin-3 in AGS gastri
Externí odkaz:
https://doaj.org/article/a78b4a36786547c299432c15e37ddf8d
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 968 (2021)
MUC1 mucin is a transmembrane glycoprotein aberrantly overexpressed and underglycosylated in most epithelium origin cancers. Combining chemotherapeutics with monoclonal antibodies toward cancer-related antigens is one of the new strategies in cancer
Externí odkaz:
https://doaj.org/article/c715c4b5794c4fdfb7fab7af5bedf2ca
Autor:
Iwona Radziejewska
Publikováno v:
Cancers. 15:2680
Aberrant glycosylation of cell surface proteins is a very common feature of many cancers. One of the glycoproteins, which undergoes specific alterations in the glycosylation of tumor cells is epithelial MUC1 mucin, which is highly overexpressed in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8d63aec93b421451c6c31b2a86c8090
https://doi.org/10.3390/cancers15102680
https://doi.org/10.3390/cancers15102680
Publikováno v:
Pharmaceuticals
Pharmaceuticals, Vol 14, Iss 973, p 973 (2021)
Volume 14
Issue 10
Pharmaceuticals, Vol 14, Iss 973, p 973 (2021)
Volume 14
Issue 10
Afzelin demonstrates anti-inflammatory and anti-cancer properties. Our purpose was to assess its influence on apoptosis, Bax, caspases, MUC1, cancer-related carbohydrate antigens, enzymes participating in their formation, and galectin-3 in AGS gastri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d6b7024f08fd0a1b19598da48c72e8
http://europepmc.org/articles/PMC8539446
http://europepmc.org/articles/PMC8539446
Publikováno v:
Pharmaceutics
Volume 13
Issue 7
Pharmaceutics, Vol 13, Iss 968, p 968 (2021)
Volume 13
Issue 7
Pharmaceutics, Vol 13, Iss 968, p 968 (2021)
MUC1 mucin is a transmembrane glycoprotein aberrantly overexpressed and underglycosylated in most epithelium origin cancers. Combining chemotherapeutics with monoclonal antibodies toward cancer-related antigens is one of the new strategies in cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909e8e0bcd07f99a7d9d04b402eb2188
Publikováno v:
International Journal of Oncology
Mucin 1 (MUC1) is a membrane‑bound, highly glycosylated protein that is overexpressed in all stages of malignant transformation. Overexpression of MUC1 together with loss of polarization and hypoglycosylation are associated with resistance to apopt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8a04813bc7b32b74b8b581bf97eef61
https://pubmed.ncbi.nlm.nih.gov/34278474
https://pubmed.ncbi.nlm.nih.gov/34278474