Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Iwig JS"'
Autor:
Roose, Jeroen, Iwig, JS, Vercoulen, Y, Das, R, Barros, T, Limnander, A, Che, Y, Pelton, JG, Wemmer, DE, Roose, JP, Kuriyan, J
Publikováno v:
Roose, Jeroen; Iwig, JS; Vercoulen, Y; Das, R; Barros, T; Limnander, A; et al.(2013). Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/5wj2r15r
RasGRP1 and SOS are Ras-specific nucleotide exchange factors that have distinct roles in lymphocyte development. RasGRP1 is important in some cancers and autoimmune diseases but, in contrast to SOS, its regulatory mechanisms are poorly understood. Ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::7888e6bdc6f99551241687484956d06b
http://www.escholarship.org/uc/item/5wj2r15r
http://www.escholarship.org/uc/item/5wj2r15r
Autor:
Shin Y; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Jeong JW; Carmot Therapeutics, Inc. 740 Heinz Avenue, Berkeley, California 94710, United States., Wurz RP; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Achanta P; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Arvedson T; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Bartberger MD; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Campuzano IDG; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Fucini R; Carmot Therapeutics, Inc. 740 Heinz Avenue, Berkeley, California 94710, United States., Hansen SK; Carmot Therapeutics, Inc. 740 Heinz Avenue, Berkeley, California 94710, United States., Ingersoll J; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Iwig JS; Carmot Therapeutics, Inc. 740 Heinz Avenue, Berkeley, California 94710, United States., Lipford JR; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Ma V; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Kopecky DJ; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., McCarter J; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., San Miguel T; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Mohr C; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Sabet S; Carmot Therapeutics, Inc. 740 Heinz Avenue, Berkeley, California 94710, United States., Saiki AY; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Sawayama A; Carmot Therapeutics, Inc. 740 Heinz Avenue, Berkeley, California 94710, United States., Sethofer S; Carmot Therapeutics, Inc. 740 Heinz Avenue, Berkeley, California 94710, United States., Tegley CM; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Volak LP; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Yang K; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Lanman BA; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Erlanson DA; Carmot Therapeutics, Inc. 740 Heinz Avenue, Berkeley, California 94710, United States., Cee VJ; Departments of Therapeutic Discovery, Oncology Research, Pharmacokinetics and Drug Metabolism, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2019 Aug 20; Vol. 10 (9), pp. 1302-1308. Date of Electronic Publication: 2019 Aug 20 (Print Publication: 2019).
Autor:
Huang HT; Department of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003., Bobst CE; Department of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003., Iwig JS; Carmot Therapeutics, Inc., San Francisco, California 94158., Chivers PT; Departments of Biosciences and Chemistry, Durham University, Durham DH1 3LE, United Kingdom., Kaltashov IA; Department of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003., Maroney MJ; Department of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003. Electronic address: mmaroney@chem.umass.edu.
Publikováno v:
The Journal of biological chemistry [J Biol Chem] 2018 Jan 05; Vol. 293 (1), pp. 324-332. Date of Electronic Publication: 2017 Nov 17.
Autor:
Vercoulen Y; Department of Anatomy, University of California, San Francisco, San Francisco, United States.; Molecular Cancer Research, Center for Molecular Medicine, UMC Utrecht, Utrecht University, Utrecht, Netherlands., Kondo Y; Department of Molecular and Cell Biology and Chemistry, University of California, Berkeley, United States.; California Institute for Quantitative Biosciences, University of California, Berkeley, United States., Iwig JS; Department of Molecular and Cell Biology and Chemistry, University of California, Berkeley, United States.; California Institute for Quantitative Biosciences, University of California, Berkeley, United States., Janssen AB; Department of Anatomy, University of California, San Francisco, San Francisco, United States., White KA; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, United States., Amini M; Molecular Cancer Research, Center for Molecular Medicine, UMC Utrecht, Utrecht University, Utrecht, Netherlands., Barber DL; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, United States., Kuriyan J; Department of Molecular and Cell Biology and Chemistry, University of California, Berkeley, United States.; California Institute for Quantitative Biosciences, University of California, Berkeley, United States.; Howard Hughes Medical Institute, University of California, Berkeley, United States.; Department of Chemistry, University of California, Berkeley, United States.; Divisions of Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, United States., Roose JP; Department of Anatomy, University of California, San Francisco, San Francisco, United States.
Publikováno v:
ELife [Elife] 2017 Sep 27; Vol. 6. Date of Electronic Publication: 2017 Sep 27.
Autor:
Christensen SM; Department of Chemistry, University of California, Berkeley, Berkeley, California, USA., Tu HL; Department of Chemistry, University of California, Berkeley, Berkeley, California, USA., Jun JE; Department of Anatomy, University of California, San Francisco, San Francisco, California, USA., Alvarez S; Department of Chemistry, University of California, Berkeley, Berkeley, California, USA., Triplet MG; Department of Chemistry, University of California, Berkeley, Berkeley, California, USA., Iwig JS; Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, USA., Yadav KK; Department of Biochemistry, New York University School of Medicine, New York, New York, USA., Bar-Sagi D; Department of Biochemistry, New York University School of Medicine, New York, New York, USA., Roose JP; Department of Anatomy, University of California, San Francisco, San Francisco, California, USA., Groves JT; Department of Chemistry, University of California, Berkeley, Berkeley, California, USA.
Publikováno v:
Nature structural & molecular biology [Nat Struct Mol Biol] 2016 Sep; Vol. 23 (9), pp. 838-46. Date of Electronic Publication: 2016 Aug 08.
Autor:
Christensen SM, Triplet MG, Rhodes C, Iwig JS, Tu HL, Stamou D; Department of Chemistry and Nano-Science Center, University of Copenhagen , Copenhagen, Denmark., Groves JT
Publikováno v:
Nano letters [Nano Lett] 2016 Apr 13; Vol. 16 (4), pp. 2890-5. Date of Electronic Publication: 2016 Mar 30.
Autor:
Lin WC; Howard Hughes Medical Institute and Departments of Chemistry and Molecular and Cell Biology, University of California, Berkeley, CA 94720., Iversen L, Tu HL, Rhodes C, Christensen SM, Iwig JS, Hansen SD, Huang WY, Groves JT
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2014 Feb 25; Vol. 111 (8), pp. 2996-3001. Date of Electronic Publication: 2014 Feb 10.
Autor:
Iwig JS; Department of Molecular and Cell Biology , University of California, Berkeley , Berkeley , United States ; California Institute for Quantitative Biosciences , University of California, Berkeley , Berkeley , United States., Vercoulen Y, Das R, Barros T, Limnander A, Che Y, Pelton JG, Wemmer DE, Roose JP, Kuriyan J
Publikováno v:
ELife [Elife] 2013 Jul 30; Vol. 2, pp. e00813. Date of Electronic Publication: 2013 Jul 30.
Autor:
Chivers PT; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, USA. pchivers@oberlin.edu, Benanti EL, Heil-Chapdelaine V, Iwig JS, Rowe JL
Publikováno v:
Metallomics : integrated biometal science [Metallomics] 2012 Oct; Vol. 4 (10), pp. 1043-50. Date of Electronic Publication: 2012 Aug 10.