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Na, K-ATPase α3 is a death target of Alzheimer patient amyloid-β assembly

Autor: Ohnishi, T, Yanazawa, M, Sasahara, T, Kitamura, Y, Hiroaki, H, Fukazawa, Y, Kii, I, Nishiyama, T, Kakita, A, Takeda, H, Takeuchi, A, Arai, Y, Ito, A, Komura, H, Hirao, H, Satomura, K, Inoue, M, Muramatsu, SI, Matsui, K, Tada, M, Sato, M, Saijo, E, Shigemitsu, Y, Sakai, S, Umetsu, Y, Goda, N, Takino, N, Takahashi, H, Hagiwara, M, Sawasaki, T, Iwasaki, G, Nakamura, Y, Nabeshima, YI, Teplow, DB, Hoshi, M, Südhof, TC

Publikováno v: Ohnishi, T; Yanazawa, M; Sasahara, T; Kitamura, Y; Hiroaki, H; Fukazawa, Y; et al.(2015). Na, K-ATPase α3 is a death target of Alzheimer patient amyloid-β assembly. Proceedings of the National Academy of Sciences of the United States of America, 112(32), E4465-E4474. doi: 10.1073/pnas.1421182112. UCLA: Retrieved from: http://www.escholarship.org/uc/item/1zx5n343

Neurodegeneration correlates with Alzheimer's disease (AD) symptoms, but the molecular identities of pathogenic amyloid β-protein (Aβ) oligomers and their targets, leading to neurodegeneration, remain unclear. Amylospheroids (ASPD) are AD patient-d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::2ca8ceecf005ebfcee7dacf44cb05bc2
http://www.escholarship.org/uc/item/1zx5n343

Computational Modeling of a Binding Conformation of the Intermediate l-Histidinal to Histidinol Dehydrogenase

Autor: Gohda, K., Ohta, D., Iwasaki, G., Ertl, P., Jacob, O.

Publikováno v: Journal of Chemical Information and Computer Sciences (now called Journal of Chemical Information and Modeling); January 22, 2001, Vol. 41 Issue: 1 p196-201, 6p

Discovery of IRL 3461: A Novel and Potent Endothelin Antagonist With Balanced ET~A/ET~B Affinity

Autor: Sakaki, J., Murata, T., Yuumoto, Y., Nakamura, I., Frueh, T., Pitterna, T., Iwasaki, G., Oda, K., Yamamura, T., Hayakawa, K.

Publikováno v: Bioorganic & Medicinal Chemistry Letters; 1998, Vol. 8 Issue: 16 p2241-2246, 6p

Crystallization and preliminary crystallographic analysis of cabbage histidinol dehydrogenase.

Autor: Cowan-Jacob, S. W., Rahuel, J., Nagai, A., Iwasaki, G., Ohta, D.

Publikováno v: Acta Crystallographica: Section D (Wiley-Blackwell); 1996, Vol. 52 Issue 6, p1188-1190, 3p