Effects of the quantity of water and milk ingested concomitantly with AS-924, a novel ester-type cephem antibiotic, on its pharmacokinetics

Autor: Masayuki Morita, Nobuhiro Mori, Fumio Matsumoto, Atsushi Sakai, Shinya Yamaji, Takayuki Takahashi, Taisuke Sugihara, Yasuhiro Akaike, Iwao Sakurai, Kazuo Yano

Publikováno v: International Journal of Antimicrobial Agents. 18:471-476

The effect of the quantity of water ingested concomitantly with drugs, on the absorption of AS-924, a novel prodrug-type cephem antibiotic, was studied in five healthy adult volunteers by a cross-over method, using cefteram-pivoxil (CTER-PI) as the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259ad3aa87046c74e38aa394e84eb91b
https://doi.org/10.1016/s0924-8579(01)00447-2

Basic and Clinical Studies of Pazufloxacin on Infectious Enteritis Research Group of T-3761 on Infectious Enteritis (Manager; Shoichiro IRIMAJIRI)

Autor: Hiroko SAGARA, Kouji YOSHIKAWA, Isao TOMIZAWA, Yoshihiko TAKIZAWA, Yoshiro NITTA, Takafumi TSUNODA, Hiroyuki FUKUDA, Tsuyoshi YAMAGUCHI, Gohta MASUDA, Masayoshi NEGISHI, Atsushi AJISAWA, Misako MURATA, Kenji OHNISHI, Shoichiro IRIMAJIRI, Mitsuo OBANA, Fumio MATSUMOTO, Takero IMAI, Iwao SAKURAI, Takayuki TAKAHASHI, Masamiki MORI, Yoshiki MIZUNO, Kohji KATOH, Shiro HOSODA, Tadao BAMBA, Masaya SASAKI, Kunio YOSHIKAWA, Shuichi HIROTANI, Takeshi OGASAWARA, Hitoshi SAKUMOTO, Yasunobu KOMAI, Hideo OOKUBO, Young Ki KIM, Shinobu NAKAJO, Hirozumi OBATA, Yoshihiro SAKAUE, Hideki YOSHIDA, Tetsushi GOTO, Tadakazu AISAKA, Motoko MIKAMI, Kazunori KAGAWA, Yatsuka IMAGAWA, Masafumi FUKUYAMA, Yoshio MATSUBARA, Makoto SAITO

Publikováno v: Journal of the Japanese Association for Infectious Diseases. 70:60-72

A clinical study was carried out on pazufloxacin (PZFX) in 137 patients including shigellosis, Salmonella enteritis, enteropathogenic Esherichia coli enteritis and cholera, and carriers of these pathogens. Antibacterial activity of PZFX against clini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c31c85459238dac2c0a38672e3d7933
https://doi.org/10.11150/kansenshogakuzasshi1970.70.60

Suppressive Effects of Minocycline on the Pituitary-Thyroid Axis in Humans

Autor: Kohya Shiba, Fumio Matsumoto, Takeo Imai, Osamu Sakai, Iwao Sakurai, Takashi Shigematsu, Yoshindo Kawaguchi

Publikováno v: Journal of Infection and Chemotherapy. 1:116-121

Minocycline has been thought to induce “black thyroid”, a condition marked by discoloration due to brown deposits. However, its effect on thyroid function in humans is still obscure. We conducted a prospective study of thyroid hormone levels in 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e605b0b0cd58e4cbe20d718ca73291a
https://doi.org/10.1007/bf02348755

[Usefulness of 7 day therapy with cefluprenam in the management of respiratory tract infections]

Autor: Kaoru SHIMADA, Mitsuhide OHMICHI, Hiroko SASAKI, Akira WATANABE, Kazuo SATO, Kosaku NAGAI, Kazuki KONISHI, Takashi OHTA, Yoshifumi MATSUURA, Hideki IKEDA, Kenichi IGARASHI, Fumihide IWATA, Koichi WADA, Michio MARUYAMA, Shigeyuki HOSHINO, Akira IWASHIMA, Yasutoshi SUZUKI, Osamu SEKINE, Nobuki AOKI, Saburo IZUMI, Toshio NAKAMURA, Toshiki IWABUCHI, Harumi SHISHIDO, Shoko TANOUE, Yuko KOMASE, Iwao SAKURAI, Kenji KASAI, Hiroyuki TERAWAKI, Michihiro TSUKUI, Keita HIRANO, Hiroyuki TANIGUCHI, Junya IKUTA, Akira YAMAGISAWA, Kunihiko GOTOH, Masashi YAMAMOTO, Mitsuo SATO, Akihisa KUMASAWA, Takashi SONODA, Jiro OKIMOTO, Makoto KIMURA, Hirohide YONEYAMA, Takayuki KARINO, Kazue FUJITA, Hideo OHBA, Takashi TSUYA, Akimasa OHUNE, Kohya SHIBA, Akira SAITOH, Hiroyuki KOBAYASHI, Toshiharu MATSUSHIMA, Shigeru KOHNO

Publikováno v: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 71(8)

Efficacy and safety of a newer injectable cephalosporin, cefluprenam (CFLP) on cases with bacterial pneumonia and chronic respiratory tract infections were evaluated at a dose of 1g (potency), d.i.d for 7 days. 1. Of 130 cases in total, 116 cases wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b632cc349a1afcefc5681c776c11e242
https://pubmed.ncbi.nlm.nih.gov/9311195

[A comparative study of cefepime for bacterial pneumonia]

Autor: Atsushi SAITO, Yoshiteru SHIGENO, Yuei IRABU, Hiroshi FUKUHARA, Soukichi ONODERA, Hitoshi NAKANO, Tetsuo SHIMIZU, Nobuhiro SASAKI, Hirotaka HASHIZUME, Yuka FUJITA, Takashi HIROSHIMA, Eiichi SAKAI, Akira SAITO, Ichiro NAKAYAMA, Yohmei HIRAGA, Mitsuhide OHMICHI, Kazuo TAKEBA, Ken OSONOI, Miyoko SAITO, Hirohisa KURODA, Masao TAMURA, Kazuki KONISHI, Yoshiaki MORI, Akiho OBARA, Kazuo OBARA, Hitoshi KOBAYASHI, Junichi OGAWA, Kunio KUDO, Munehiko ISHII, Masakichi MOTOMIYA, Akira WATANABE, Yoshihiro HONDA, Yutaka TOKUE, Mitsunobu HONMA, Masataka KATSU, Keisuke KUGA, Junzaburou KABE, Hitoshi ARIOKA, Hiroko ARIOKA, Masaru KOYAMA, Kouichiro NAKATA, Yoshitaka NAKAMORI, Osamu SAKAI, Jingorou SHIMADA, Kohya SHIBA, Masaki YOSHIDA, Hiroichi TANIMOTO, Tetsuo OKAMURA, Hiroyuki KOBAYASHI, Toru SAKAYORI, Hiroshi OSHITANI, Hiroaki TAKEDA, Shoichiro IRIMAJIRI, Yasuo MATSUOKA, Mitsuo OBANA, Takao OKUBO, Hirotada IKEDA, Fumio MATSUMOTO, Iwao SAKURAI, Takayuki TAKAHASHI, Shigeki ODAGIRI, Hiroshi TAKAHASHI, Kenichi TAKAHASHI, Yasutsugu AMANO, Takashi SAKUMA, Masaaki ARAKAWA, Koichi WADA, Takashi KAWASHIMA, Masanaga TAKATO, Shigeyuki HOSHINO, Osamu SEKINE, Yasutoshi SUZUKI, Toshihiko TAKEUCHI, Yoshimitsu HAYASHI, Kazuhide YAMAMOTO, Toshihiko YAMAMOTO, Kanzo SUZUKI, Toru MATSUURA, Satoru ADACHI, Fumiyuki KUZE, Takako MURAYAMA, Nobuo INABA, Yoshio ODA, Akira KAGIOKA, Fumio MIKI, Rinzo SOEJIMA, Yoshihito NIKI, Jiro HINO, Masaru SUMI, Toshiharu MATSUSHIMA, Masayoshi KAWANISHI, Makoto KIMURA, Shunkichi HIRAKI, Yohichi WATANABE, Masashi ARAKI, Takao SASAKI, Yukio MATSUMOTO, Yuji SUGIMOTO, Hidemi TERAMOTO, Michiro YAMAKIDO, Kenji HASEGAWA, Takashi TSUYA, Kenichiro SADAMOTO, Masao KUWABARA, Masanobu OKADA, Kenichi ARITA, Masao DOI, Kazuhiro DAIDO, Jitsuro YANAGIDA, Kenichiro WATANABE, Yuichi ATA, Motohiro SUGIHARA, Masato YUKUTAKE, Kouichi AWAYA, Yoshihisa IHARA, Yoshihiro SAWAE, Nobuyuki SHIMONO, Yukio KUMAGAI, Takahito HIROSE, Kei SATO, Kohtaro OHIZUMI, Youichiro ICHIKAWA, Masako TANAKA, Yoshiyuki MITSUTAKE, Kazuma FUJINO, Mikio KUBUSHIRO, Toshihiro HIGASHI, Kohei HARA, Shigeru KOHNO, Hironobu KOGA, Mitsuo KAKU, Keizo MATSUMOTO, Kazunori OHISHI, Kiyoshi SHIMA, Shinobu TAKENAKA, Masaru NASU, Yoichiro GOTO, Tohru YAMAZAKI, Hiroyuki NAGAI, Takayoshi TASHIRO, Hiroshi NAGAOKA, Kaoru NAKAMA, Nobuya OGAWA, Nobuchika KUSANO

Publikováno v: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 66(7)

The efficacy, safety and usefulness of cefepime (CFPM), a new cephem antibiotic, in bacterial pneumonia, were evaluated in a comparative study against ceftazidime (CAZ). Each drug was administered by intravenous drip infusion at a dose of 1.0 g (nomi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184e40e9efdf2d2d172feaf4e0c0f613
https://pubmed.ncbi.nlm.nih.gov/1431364