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Autor:
Kiyoshi Ameno, Hiroshi Kinoshita, Iwao Jiri, David J. Roberts, Toni L. Coventry, David S. Jessop, Michael S. Harbuz, David P. Finn
Publikováno v:
Alcohol and Alcoholism. 36:59-64
— Cyanamide is a potent inhibitor of aldehyde dehydrogenase (ALDH: EC 1.2.1.3) used in the treatment of alcoholics. In the presence of ethanol, cyanamide causes an accumulation of acetaldehyde, a highly toxic metabolite of ethanol, with unpleasant