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Publikováno v:
Chemical and Pharmaceutical Bulletin. 28:2609-2613
Eight metabolites (M-1-M-6, M-8, M-9) of 2-(N-benzyl-N-methylamino)ethyl methyl 2, 6-dimethyl-4-(m-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate hydrochloride (YC-93) were synthesized and the structures of the metabolites were established by c
Autor:
Peter L. Chang, Bruce B. Blidner, Kozo Takahashi, Ioannis K. Stamos, Iwanami Masaru, Donald C. Dittmer, Amy I. Tsai
Publikováno v:
Journal of the American Chemical Society. 98:2795-2803
Autor:
Jun Matsumoto, Hidenori Iwamoto, Kiyoshi Murase, Tamazawa Kazuharu, Kozo Takahashi, Iwanami Masaru, Murakami Masuo
Publikováno v:
Bulletin of the Chemical Society of Japan. 41:628-633
A new method for the synthesis of 2-acetyl-3, 4-diethoxycarbonylpyrrole and its derivatives by the Diels-Alder reaction is described, and the reaction mechanism of their formation is discussed.
Publikováno v:
Bulletin of the Chemical Society of Japan; January 1968, Vol. 41 Issue: 1 p161-165, 5p
Autor:
Murakami, Masuo, Takahashi, Kozo, Matsumoto, Jun, Tamazawa, Kazuharu, Murase, Kiyoshi, Iwamoto, Hidenori, Iwanami, Masaru
Publikováno v:
Bulletin of the Chemical Society of Japan; March 1968, Vol. 41 Issue: 3 p628-633, 6p
Autor:
Tadao Shibanuma, Kuniichiro Yano, Fujimoto Masaharu, Tamazawa Kazuharu, Nagano Yoshinobu, Yamazaki Atsuki, Iwanami Masaru, Maeda Tetsuya, Noriaki Nagano
Publikováno v:
Chemicalpharmaceutical bulletin. 28(9)
A novel intramolecular rearrangement of isothiazolethioacetamides into 1, 3-dithietanecarboxamides is described, together with the synthesis of a new cephamycin derivative (YM-09330) having a 1, 3-dithietane structure at the 7β-position. This compou
Autor:
Ryutaro Kawai, Toichi Takenaka, Tamazawa Kazuharu, Murakami Masuo, Fujimoto Masaharu, Kozo Takahashi, Iwanami Masaru, Tadao Shibanuma
Publikováno v:
Chemicalpharmaceutical bulletin. 27(6)
Several kinds of water-soluble dihydropyridine vasodilators were prepared and their vasodilating activities were evaluated. Among them, 2-(N-benzyl-N-methylamino)-ethyl methyl 2, 6-dimethyl-4-(m-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate hy
Autor:
Ryutaro Kawai, Toichi Takenaka, Fujimoto Masaharu, Tamazawa Kazuharu, Kozo Takahashi, Murakami Masuo, Iwanami Masaru, Tadao Shibanuma
Publikováno v:
Chemischer Informationsdienst. 10
Several kinds of water-soluble dihydropyridine vasodilators were prepared and their vasodilating activities were evaluated. Among them, 2-(N-benzyl-N-methylamino)-ethyl methyl 2, 6-dimethyl-4-(m-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate hy
Publikováno v:
Chemischer Informationsdienst. 12
Der Nitrobenzaldehyd (I) reagiert mit Acetessigester (II) und dem Enaminoester (III) zum Dihydropyridin (IV), das zu (V) alkyliert wird.