Cryo-EM structures of a LptDE transporter in complex with Pro-macrobodies offer insight into lipopolysaccharide translocation

Autor: Mathieu Botte, Dongchun Ni, Stephan Schenck, Iwan Zimmermann, Mohamed Chami, Nicolas Bocquet, Pascal Egloff, Denis Bucher, Matilde Trabuco, Robert K. Y. Cheng, Janine D. Brunner, Markus A. Seeger, Henning Stahlberg, Michael Hennig

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)

Lateral opening of the LptDE transporter in the outer membrane of Gram-negative bacteria is necessary for insertion of lipopolysaccharides. Here, Botte et al. report a cryo-EM structure of a partially opened LptDE transporter, in complex with rigid c

Externí odkaz: https://doaj.org/article/25e3d626c5e9434d8732b67049815a5b

Atomic Layer-Deposited Aluminum Oxide Hinders Iodide Migration and Stabilizes Perovskite Solar Cells

Autor: Chittaranjan Das, Malgorzata Kot, Tim Hellmann, Carolin Wittich, Eric Mankel, Iwan Zimmermann, Dieter Schmeisser, Mohammad Khaja Nazeeruddin, Wolfram Jaegermann

Publikováno v: Cell Reports Physical Science, Vol 1, Iss 7, Pp 100112- (2020)

Summary: Iodide migration causes degradation of the perovskite solar cells. Here, we observe the direct migration of iodide into the hole-transport layer in a device. We demonstrate that ultrathin room temperature atomic layer-deposited Al2O3 on the

Externí odkaz: https://doaj.org/article/3253a11e0683462aa1c515994c0db26f

Industrially Compatible Fabrication Process of Perovskite-Based Mini-Modules Coupling Sequential Slot-Die Coating and Chemical Bath Deposition

Autor: Iwan Zimmermann, Marion Provost, Salim Mejaouri, Marc Al Atem, Alexandre Blaizot, Aurélien Duchatelet, Stéphane Collin, Jean Rousset

Publikováno v: ACS Applied Materials & Interfaces. 14:11636-11644

To upscale the emerging perovskite photovoltaic technology to larger-size modules, industrially relevant deposition techniques need to be developed. In this work, the deposition of tin oxide used as an electron extraction layer is established using c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1815ed33d013ebab29792a6e1e4b7869
https://doi.org/10.1021/acsami.1c24558

Crystal structures of isotypic poly[bis(benzimidazolium) [tetra-μ-iodido-stannate(II)]] and poly[bis(5,6-difluorobenzimidazolium) [tetra-μ-iodido-stannate(II)]]

Autor: Iwan Zimmermann, Tony D. Keene, Jürg Hauser, Silvio Decurtins, Shi-Xia Liu

Publikováno v: Acta Crystallographica Section E, Vol 70, Iss 10, Pp 178-182 (2014)

The isostructural title compounds, {(C7H7N2)2[SnI4]}n, (1), and {(C7H5F2N2)2[SnI4]}n, (2), show a layered perovskite-type structure composed of anionic {[SnI4]2−}n sheets parallel to (100), which are decorated on both sides with templating benzimid

Externí odkaz: https://doaj.org/article/ec0d6ccea9bd4004a090086cc0c96033

Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance

Autor: Justin D Walter, Melanie Scherer, Cedric A J Hutter, Alisa A Garaeva, Iwan Zimmermann, Marianne Wyss, Jan Rheinberger, Yelena Ruedin, Jennifer C Earp, Pascal Egloff, Michèle Sorgenfrei, Lea M Hürlimann, Imre Gonda, Gianmarco Meier, Sille Remm, Sujani Thavarasah, Geert van Geest, Rémy Bruggmann, Gert Zimmer, Dirk J Slotboom, Cristina Paulino, Philippe Plattet, Markus A Seeger

Publikováno v: Walter, Justin D; Scherer, Melanie; Hutter, Cedric A J; Garaeva, Alisa A; Zimmermann, Iwan; Wyss, Marianne; Rheinberger, Jan; Ruedin, Yelena; Earp, Jennifer C; Egloff, Pascal; Sorgenfrei, Michèle; Hürlimann, Lea M; Gonda, Imre; Meier, Gianmarco; Remm, Sille; Thavarasah, Sujani; van Geest, Geert; Bruggmann, Rémy; Zimmer, Gert; Slotboom, Dirk J; ... (2022). Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance. EMBO reports, 23(4), e54199. EMBO press 10.15252/embr.202154199
Embo Reports, 23(4):e54199. Wiley

The ongoing COVID-19 pandemic represents an unprecedented global health crisis. Here, we report the identification of a synthetic nanobody (sybody) pair, Sb#15 and Sb#68, that can bind simultaneously to the SARS-CoV-2 spike RBD and efficiently neutra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309263edeedbda3c81f46bed9ea534c3
https://research.rug.nl/en/publications/a7bdcefa-70e3-48b3-8b5d-0a0f73a9207c