Interleukin-1α Is a Critical Mediator of the Response of Human Bronchial Fibroblasts to Eosinophilic Inflammation

Autor: Ksenija Bernau, Jonathan P. Leet, Heather Floerke, Ellen M. Bruhn, Andrea L. Noll, Ivy S. McDermott, Stephane Esnault, Nizar N. Jarjour, Nathan Sandbo

Publikováno v: Cells, Vol 10, Iss 3, p 528 (2021)

Eosinophils contribute to allergic inflammation in asthma in part via elaboration of a complex milieu of soluble mediators. Human bronchial fibroblasts (HBF) respond to stimulation by these mediators by acquiring a pro-inflammatory profile including

Externí odkaz: https://doaj.org/article/33b79f07f0464544af065d283c263f5c

Genetic influences on the human oral microbiome

Autor: Ivy S McDermott, Robin P. Corley, Matthew B. McQueen, Kenneth Krauter, Matthew C. Keller, Brooke M. Huibregtse, Rob Knight, Brittany A. Demmitt, John K. Hewitt

Publikováno v: BMC Genomics, Vol 18, Iss 1, Pp 1-15 (2017)
BMC genomics, vol 18, iss 1
Demmitt, BA; Corley, RP; Huibregtse, BM; Keller, MC; Hewitt, JK; McQueen, MB; et al.(2017). Genetic influences on the human oral microbiome. BMC GENOMICS, 18. doi: 10.1186/s12864-017-4008-8. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/38m5h9vt
BMC Genomics

Background The human oral microbiome is formed early in development. Its composition is influenced by environmental factors including diet, substance use, oral health, and overall health and disease. The influence of human genes on the composition an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::235f90f763f68ce03f693a732590eb6f
http://link.springer.com/article/10.1186/s12864-017-4008-8